Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Javier E. Sierra-Pagán"'
Autor:
Young Geun Choi, Xiao Ma, Satyabrata Das, Javier E. Sierra-Pagan, Thijs Larson, Wuming Gong, Hesham A. Sadek, Jianyi (Jay) Zhang, Mary G. Garry, Daniel J. Garry
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract ETV2 is an essential transcription factor as Etv2 null murine embryos lack all vasculature, blood and are lethal early during embryogenesis. Previous studies have established that ETV2 functions as a pioneer factor and directly reprograms fi
Externí odkaz:
https://doaj.org/article/6c63c796c8f040ff800579252ce4c571
Autor:
Parisha P. Shah, Rajan Jain, Nicole Dubois, Lauren J. Manderfield, Mitchell A. Lazar, Jonathan A. Epstein, Michael Morley, Edward E. Morrisey, Zheng Sun, Cheryl L. Smith, Andrey Poleshko, Qiaohong Wang, Mudit Gupta, Li Li, Damelys Calderon, Haig Aghajanian, Apoorva Babu, Jamie L. Ifkovits, Javier E. Sierra-Pagán
Publikováno v:
Cell. 171(3)
Progenitor cells differentiate into specialized cell types through coordinated expression of lineage-specific genes and modification of complex chromatin configurations. We demonstrate that a histone deacetylase (Hdac3) organizes heterochromatin at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d8f09780b2baea8d6ecf0d2d2f3062
https://pubmed.ncbi.nlm.nih.gov/29033129
https://pubmed.ncbi.nlm.nih.gov/29033129
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Cardiovascular disease (CVD) remains the number one cause of death worldwide. Ischemic heart disease contributes to heart failure and has considerable morbidity and mortality. Therefore, alternative therapeutic strategies are urgently needed. One cla
Externí odkaz:
https://doaj.org/article/a61902f7240d4add909d2d92c2348b9c
Autor:
Bhairab N. Singh, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Javier E. Sierra-Pagan, Demetris Yannopoulos, Erik Skie, Pruthvi Shah, Mary G. Garry, Daniel J. Garry
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Etv2, an Ets-transcription factor, governs the specification of the earliest hemato-endothelial progenitors during embryogenesis. While the transcriptional networks during hemato-endothelial development have been well described, the mechanis
Externí odkaz:
https://doaj.org/article/eda0d5c70def493b993477499d9dd848
Autor:
Yamil Gerena, Raissa Menéndez-Delmestre, Andrea Delgado-Nieves, Joyce Vélez, Jarold Méndez-Álvarez, Javier E. Sierra-Pagan, Richard L. Skolasky, Lisa Henderson, Avindra Nath, Valerie Wojna
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Previously, we found that high levels of soluble insulin receptor (sIR) in the cerebrospinal fluid (CSF) of an HIV-infected women cohort were associated with the presence and severity of HIV-associated neurocognitive disorders (HAND). In this study w
Externí odkaz:
https://doaj.org/article/5b7c17b64fc6411bba46dedd6254aad8