Výsledky vyhledávání - "Javier Díaz-Alonso"

Akademický článek

Autor: Wucheng Tao, Joel Lee, Xiumin Chen, Javier Díaz-Alonso, Jing Zhou, Samuel Pleasure, Roger A Nicoll

Publikováno v: eLife, Vol 10 (2021)

Long-term potentiation (LTP) is arguably the most compelling cellular model for learning and memory. While the mechanisms underlying the induction of LTP (‘learning’) are well understood, the maintenance of LTP (‘memory’) has remained content

Externí odkaz: https://doaj.org/article/139babb4c9564093be872a3227250095

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Akademický článek

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

Autor: Javier Díaz-Alonso, Wade Morishita, Salvatore Incontro, Jeffrey Simms, Julia Holtzman, Michael Gill, Lennart Mucke, Robert C Malenka, Roger A Nicoll

Publikováno v: eLife, Vol 9 (2020)

We tested the proposal that the C-terminal domain (CTD) of the AMPAR subunit GluA1 is required for LTP. We found that a knock-in mouse lacking the CTD of GluA1 expresses normal LTP and spatial memory, assayed by the Morris water maze. Our results sup

Externí odkaz: https://doaj.org/article/2a687e03a6294615a01f92954f148df5

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Akademický článek

The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

Autor: Salvatore Incontro, Javier Díaz-Alonso, Jillian Iafrati, Marta Vieira, Cedric S. Asensio, Vikaas S. Sohal, Katherine W. Roche, Kevin J. Bender, Roger A. Nicoll

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-21 (2018)

Calcium-calmodulin-dependent protein kinase II (CaMKII) is well known for its roles in synaptic plasticity. Using a series of molecular replacement experiments, the authors show that the kinase function of CaMKII is required for long-term plasticity

Externí odkaz: https://doaj.org/article/5fb48f87db034bfe9e462aad3de3908e

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Akademický článek

Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia

Autor: Daniel García-Rincón, Javier Díaz-Alonso, Juan Paraíso-Luna, Zaira Ortega, José Aguareles, Adán de Salas-Quiroga, Cristina Jou, Inmaculada de Prada, Verónica Martínez-Cerdeño, Eleonora Aronica, Manuel Guzmán, María Ángeles Pérez-Jiménez, Ismael Galve-Roperh

Publikováno v: Frontiers in Pharmacology, Vol 9 (2019)

Alterations of the PI3K/Akt/mammalian target of rapamycin complex 1 (mTORC1) signaling pathway are causally involved in a subset of malformations of cortical development (MCDs) ranging from focal cortical dysplasia (FCD) to hemimegalencephaly and meg

Externí odkaz: https://doaj.org/article/2a143246417649ae9526920cece207f1

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Akademický článek

Author Correction: The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms

Autor: Salvatore Incontro, Javier Díaz-Alonso, Jillian Iafrati, Marta Vieira, Cedric S. Asensio, Vikaas S. Sohal, Katherine W. Roche, Kevin J. Bender, Roger A. Nicoll

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-2 (2018)

The originally published version of this Article contained errors in Figure 5, for which we apologise. In panel c, the scatter graph was inadvertently replaced with a scatter graph comprising a subset of data points from panel d. Furthermore, the leg

Externí odkaz: https://doaj.org/article/285590a6c6aa43ccbe9bb83ced51b30c

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