Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Javier Alegre"'
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S666- (2023)
Externí odkaz:
https://doaj.org/article/174a0b67409c4022865ab5a9c2da95dc
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S772- (2023)
Externí odkaz:
https://doaj.org/article/9457397e46304a059aa047b8b8650c25
Autor:
Mikel Val-Calvo, Javier Alegre-Cortés, Rocio Lopez Peco, Cristina Soto Sanchez, Jesualdo Fernández-Breis, Eduardo Fernández Jover
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S804- (2023)
Externí odkaz:
https://doaj.org/article/c004f25173c74ef3aa08a364fe99fa9f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13199 (2023)
Alpha-synucleinopathies (α-synucleinopathies) such as Parkinson’s disease (PD), Parkinson’s disease dementia (PDD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are all characterized by aggregates of alpha-synuclein (α-syn
Externí odkaz:
https://doaj.org/article/77a5a009adfe4026bb3f41bc79f561bd
Autor:
Nora Bengoa-Vergniory, Elisavet Velentza-Almpani, Ana Maria Silva, Connor Scott, Mariana Vargas-Caballero, Magdalena Sastre, Richard Wade-Martins, Javier Alegre-Abarrategui
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-20 (2021)
Abstract Background Multimerization is a key process in prion-like disorders such as Alzheimer’s disease (AD), since it is a requirement for self-templating tau and beta-amyloid amyloidogenesis. AT8-immunohistochemistry for hyperphosphorylated tau
Externí odkaz:
https://doaj.org/article/95ebe064b735404f8b092f9ef16f8cee
Autor:
Devika Agarwal, Cynthia Sandor, Viola Volpato, Tara M. Caffrey, Jimena Monzón-Sandoval, Rory Bowden, Javier Alegre-Abarrategui, Richard Wade-Martins, Caleb Webber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The substantia nigra is important in neurological disease, particularly movement disorders. Here the authors provide a single cell transcriptomic atlas for the human substantia nigra.
Externí odkaz:
https://doaj.org/article/b479fe2c43c740f2a5200c552a91eb31
Autor:
David Gordon, Ruxandra Dafinca, Jakub Scaber, Javier Alegre-Abarrategui, Lucy Farrimond, Connor Scott, Daniel Biggs, Louisa Kent, Peter L. Oliver, Benjamin Davies, Olaf Ansorge, Richard Wade-Martins, Kevin Talbot
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 148-162 (2019)
Mutations in the gene encoding the RNA-binding protein TDP-43 cause amyotrophic lateral sclerosis (ALS), clinically and pathologically indistinguishable from the majority of ‘sporadic’ cases of ALS, establishing altered TDP-43 function and distri
Externí odkaz:
https://doaj.org/article/192a3fbab9434e70aeee4440b8061102
Publikováno v:
eLife, Vol 10 (2021)
Behavioral studies differentiate the rodent dorsal striatum (DS) into lateral and medial regions; however, anatomical evidence suggests that it is a unified structure. To understand striatal dynamics and basal ganglia functions, it is essential to cl
Externí odkaz:
https://doaj.org/article/b107284229c149f4b1e5c3a4a11bfd4f
Autor:
Benjamin H.M. Hunn, Siv Vingill, Sarah Threlfell, Javier Alegre-Abarrategui, Morgane Magdelyns, Thierry Deltheil, Nora Bengoa-Vergniory, Peter L. Oliver, Milena Cioroch, Natalie M. Doig, David M. Bannerman, Stephanie J. Cragg, Richard Wade-Martins
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 920-931.e7 (2019)
Summary: Parkinson’s disease (PD) is characterized by the death of dopamine neurons in the substantia nigra pars compacta (SNc) and accumulation of α-synuclein. Impaired autophagy has been implicated and activation of autophagy proposed as a treat
Externí odkaz:
https://doaj.org/article/173e703e2233467d9c3680e7a98ca772
Autor:
Manuel Cabrera, Mónica López-Alonso, Laura Garach, Javier Alegre, Javier Ordoñez, Francisco Agrela
Publikováno v:
Materials, Vol 14, Iss 6, p 1466 (2021)
The management of different industrial by-products, such as recycled aggregates from construction and demolition waste and alumina by-products, as well as the reduction of landfill deposits by incorporating these products in a second life cycle, were
Externí odkaz:
https://doaj.org/article/87ec70011b0a426ba20947061e16ea00