Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Javier A. Belmont-Díaz"'
Autor:
Christian Espinosa-Bustos, Mariana Ortiz Pérez, Alonzo Gonzalez-Gonzalez, Ana María Zarate, Gildardo Rivera, Javier A. Belmont-Díaz, Emma Saavedra, Mauricio A. Cuellar, Karina Vázquez, Cristian O. Salas
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1121 (2022)
To develop novel chemotherapeutic alternatives for the treatment of Chagas disease, in this study, a set of new amino naphthoquinone derivatives were synthesised and evaluated in vitro on the epimastigote and trypomastigote forms of Trypanosoma cruzi
Externí odkaz:
https://doaj.org/article/bbb4bd96a47e4581b9ab2d5f9e1a5fdd
Autor:
Diana Xochiquetzal Robledo-Cadena, Marco Antonio García-Amezcua, Javier Alejandro Belmont-Díaz, Rafael Moreno-Sánchez, Alhelí Adán-Ladrón de Guevara, Silvia Cecilia Pacheco-Velázquez, Juan Carlos Gallardo-Pérez, Sara Rodríguez-Enríquez, Jorge Luis Vargas-Navarro
Publikováno v:
Current Medicinal Chemistry. 29:2719-2735
Background: The major hurdles for successful cancer treatment are drug resistance and invasiveness developed by breast cancer stem cells (BCSC). Objective: As these two processes are highly energy-dependent, the identification of the main ATP supplie
Autor:
Diana Xochiquetzal Robledo-Cadena, Juan Carlos Gallardo-Pérez, Víctor Dávila-Borja, Silvia Cecilia Pacheco-Velázquez, Javier Alejandro Belmont-Díaz, Stephen John Ralph, Betsy Alejandra Blanco-Carpintero, Rafael Moreno-Sánchez, Sara Rodríguez-Enríquez
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 463 (2020)
This study shows that the non-steroidal anti-inflammatory drug (NSAID) celecoxib and its non-cyclooxygenase-2 (COX2) analogue dimethylcelecoxib (DMC) exert a potent inhibitory effect on the growth of human cervix HeLa multi-cellular tumor spheroids (
Externí odkaz:
https://doaj.org/article/134dac971f804a488c2cc2d6398ae07c
Selection of Functional Quorum Sensing Systems by Lysogenic Bacteriophages in Pseudomonas aeruginosa
Autor:
Miguel A. Saucedo-Mora, Paulina Castañeda-Tamez, Adrián Cazares, Judith Pérez-Velázquez, Burkhard A. Hense, Daniel Cazares, Wendy Figueroa, Marco Carballo, Gabriel Guarneros, Berenice Pérez-Eretza, Nelby Cruz, Yoshito Nishiyama, Toshinari Maeda, Javier A. Belmont-Díaz, Thomas K. Wood, Rodolfo García-Contreras
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Quorum sensing (QS) in Pseudomonas aeruginosa coordinates the expression of virulence factors, some of which are used as public goods. Since their production is a cooperative behavior, it is susceptible to social cheating in which non-cooperative QS
Externí odkaz:
https://doaj.org/article/66c04e7eb65b4ebc95ecade403fbc8d8
Autor:
Sara Rodríguez-Enríquez, Álvaro Marín-Hernández, Juan Carlos Gallardo-Pérez, Silvia Cecilia Pacheco-Velázquez, Javier Alejandro Belmont-Díaz, Diana Xochiquetzal Robledo-Cadena, Jorge Luis Vargas-Navarro, Norma Angélica Corona de la Peña, Emma Saavedra, Rafael Moreno-Sánchez
Publikováno v:
Cells, Vol 8, Iss 10, p 1225 (2019)
Cancer development, growth, and metastasis are highly regulated by several transcription regulators (TRs), namely transcription factors, oncogenes, tumor-suppressor genes, and protein kinases. Although TR roles in these events have been well characte
Externí odkaz:
https://doaj.org/article/8529293085fa4a16ae0d175532a83e1c
Autor:
Luz Hernández-Esquivel, Alvaro Marín-Hernández, Rebeca López-Marure, Sara Rodríguez-Enríquez, Ileana Hernández-Reséndiz, Juan Carlos Gallardo-Pérez, Diana Xochiquetzal Robledo-Cadena, Silvia Cecilia Pacheco-Velázquez, Rosina Sánchez-Thomas, Jorge D. García-García, Javier Alejandro Belmont-Díaz, Rafael Moreno-Sánchez
Publikováno v:
Toxicology and Applied Pharmacology. 370:65-77
The resveratrol (RSV) efficacy to affect the proliferation of several cancer cell lines was initially examined. RSV showed higher potency to decrease growth of metastatic HeLa and MDA-MB-231 (IC50 = 200–250 μM) cells than of low metastatic MCF-7,
Autor:
Javier Alejandro Belmont-Díaz, Sara Rodríguez-Enríquez, Víctor M. Dávila-Borja, Juan Carlos Gallardo-Pérez, Betsy Alejandra Blanco-Carpintero, Rafael Moreno-Sánchez, Silvia Cecilia Pacheco-Velázquez, Stephen John Ralph, Diana Xochiquetzal Robledo-Cadena
Publikováno v:
Pharmaceuticals
Volume 13
Issue 12
Pharmaceuticals, Vol 13, Iss 463, p 463 (2020)
Volume 13
Issue 12
Pharmaceuticals, Vol 13, Iss 463, p 463 (2020)
This study shows that the non-steroidal anti-inflammatory drug (NSAID) celecoxib and its non-cyclooxygenase-2 (COX2) analogue dimethylcelecoxib (DMC) exert a potent inhibitory effect on the growth of human cervix HeLa multi-cellular tumor spheroids (
Autor:
Rafael Coria-Jiménez, Viviana Sanchez-Torres, Vanesa Angarita-Zapata, Javier Alejandro Belmont-Díaz, Adrian Cazares, Toshinari Maeda, Ricardo Jasso-Chávez, Rodolfo García-Contreras, Arturo Tovar-García, Luis Esaú López-Jácome
Publikováno v:
Archives of microbiology. 202(3)
The repurposing of gallium nitrate as an antibacterial, a drug used previously for the treatment of hypercalcemia, is a plausible alternative to combat infections by Pseudomonas aeruginosa, since it has antipseudomonal properties in vitro and in vivo
Autor:
Jesús Campos-García, Oscar Medina-Contreras, Belem Yoval-Sánchez, José S. Rodríguez-Zavala, Héctor Quezada, Javier A. Belmont-Díaz, Luis Francisco Calleja
Publikováno v:
Biochimica et biophysica acta. General subjects. 1864(1)
Background Accumulation of lipid aldehydes plays a key role in the etiology of human diseases where high levels of oxidative stress are generated. In this regard, activation of aldehyde dehydrogenases (ALDHs) prevents oxidative tissue damage during i
Autor:
Paula Licona-Limón, Thomas K. Wood, Mariano Martínez-Vázquez, Melissa Hernández-Durán, Rafael Franco-Cendejas, Luis Esaú López-Jácome, Jose L. Ramos-Balderas, Martha Yumiko Cruz-Muñiz, Javier Alejandro Belmont-Díaz, Rodolfo García-Contreras
Publikováno v:
International Journal of Antimicrobial Agents. 49:88-92
Acinetobacter baumannii is an emergent opportunistic bacterial pathogen responsible for recalcitrant infections owing to its high intrinsic tolerance to most antibiotics; therefore, suitable strategies to treat these infections are needed. One plausi