Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Javier, de Castro"'
Autor:
Rocío Rosas-Alonso, Julian Colmenarejo-Fernández, Olga Pernía, Miranda Burdiel, Carlos Rodríguez-Antolín, Itsaso Losantos-García, Tania Rubio, Rocío Moreno-Velasco, Isabel Esteban-Rodríguez, Virginia Martínez-Marín, Paloma Yubero, Nicolas Costa-Fraga, Angel Díaz-Lagares, Rafael López-López, Eva Díaz-Martin, Juan F. García, Catalina Vivancos Sánchez, Maria Luisa Gandía-González, Gema Moreno-Bueno, Javier de Castro, Inmaculada Ibánez de Cáceres
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Glioblastoma (GB) is a devastating tumor of the central nervous system characterized by a poor prognosis. One of the best-established predictive biomarker in IDH-wildtype GB is O6-methylguanine-DNA methyltransferase (MGMT) methylation (mMGMT
Externí odkaz:
https://doaj.org/article/e4a8484a046145d48a70e38e2c8d1575
Autor:
Esther Conde, MD, PhD, Susana Hernandez, PhD, Jose Luis Rodriguez Carrillo, MD, Rebeca Martinez, APT, Marta Alonso, APT, Daniel Curto, MD, Beatriz Jimenez, MD, Alejandra Caminoa, MD, PhD, Amparo Benito, MD, Pilar Garrido, MD, PhD, Sergi Clave, PhD, Edurne Arriola, MD, PhD, Isabel Esteban-Rodriguez, MD, PhD, Javier De Castro, MD, PhD, Irene Sansano, MD, Enriqueta Felip, MD, PhD, Federico Rojo, MD, PhD, Manuel Dómine, MD, PhD, Ihab Abdulkader, MD, PhD, Jorge Garcia-Gonzalez, MD, Cristina Teixido, PhD, Noemi Reguart, MD, PhD, Desamparados Compañ, MD, PhD, Amelia Insa, MD, Nuria Mancheño, MD, PhD, Sarai Palanca, MD, PhD, Oscar Juan-Vidal, MD, PhD, Nuria Baixeras, MD, Ernest Nadal, MD, PhD, Maria Cebollero, MD, Antonio Calles, MD, Paloma Martin, MD, PhD, Clara Salas, MD, PhD, Mariano Provencio, MD, PhD, Ignacio Aranda, MD, PhD, Bartomeu Massuti, MD, Laura Lopez-Vilaro, MD, Margarita Majem, MD, PhD, Luis Paz-Ares, MD, PhD, Fernando Lopez-Rios, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 5, Iss 4, Pp 100653- (2024)
Introduction: RET inhibitors with impressive overall response rates are now available for patients with NSCLC, yet the identification of RET fusions remains a difficult challenge. Most guidelines encourage the upfront use of next-generation sequencin
Externí odkaz:
https://doaj.org/article/a3e58ca9d39948fda3972ff1d75a8f34
Autor:
Miranda Burdiel, Julia Jiménez, Carlos Rodríguez-Antolín, Álvaro García-Guede, Olga Pernía, Ana Sastre-Perona, Rocío Rosas-Alonso, Julián Colmenarejo, Carmen Rodríguez-Jiménez, María Dolores Diestro, Virginia Martínez-Marín, Oliver Higueras, Patricia Cruz, Itsaso Losantos-García, Héctor Peinado, Olga Vera, Javier de Castro, Inmaculada Ibáñez de Cáceres
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-5 (2023)
Abstract Small extracellular vesicles (sEVs) in the blood of cancer patients contain higher amounts of tumor markers than those identified as free-circulating. miRNAs have significant biomedical relevance due to their high stability and feasible dete
Externí odkaz:
https://doaj.org/article/fb3fd8538ff04f0a980527d02e7153c5
Autor:
Javier De Castro, Amelia Insa, Roberto Collado-Borrell, Vicente Escudero-Vilaplana, Alex Martínez, Elena Fernandez, Ivana Sullivan, Natalia Arrabal, David Carcedo, Alba Manzaneque
Publikováno v:
BMC Pulmonary Medicine, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background There are scarce data of the costs of non-small cell lung cancer (NSCLC) recurrence in Spain. The objective of this study is to assess the economic burden of disease recurrence, for both locoregional and/or metastatic relapses, af
Externí odkaz:
https://doaj.org/article/6b5d735a63a64f3c8aa7226d4eca7c2b
Autor:
Darío Sanchez-Cabrero, Álvaro Garcia-Guede, Miranda Burdiel, Olga Pernía, Julián Colmenarejo-Fernandez, Laura Gutierrez, Oliver Higuera, Isabel Esteban Rodriguez, Rocío Rosas-Alonso, Carlos Rodriguez-Antolín, Itsaso Losantos-García, Olga Vera, Javier De Castro-Carpeño, Inmaculada Ibanez de Caceres
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11464 (2023)
Despite advances in non-small cell lung cancer (NSCLC) research, this is still the most common cancer type that has been diagnosed up to date. microRNAs have emerged as useful clinical biomarkers in both tissue and liquid biopsy. However, there are n
Externí odkaz:
https://doaj.org/article/c82e7bcbdbe64a4e99943c7310982c98
Autor:
Amelia Insa, Mariano Provencio, Bartomeu Massutí, Margarita Majem, Delvys Rodriguez-Abreu, Manuel Cobo, Manuel Dómine, Ernest Nadal, Belén Sierra-Rodero, Alberto Cruz-Bermúdez, Alex Martinez-Marti, Javier De Castro Carpeño, Guillermo López Vivanco, Edel Del Barco, Nuria Viñolas, Isidoro Barneto Aranda, Marta Casarrubios, Atocha Romero, Reyes Bernabe, María del Rosario García-Campelo, Martín Lázaro-Quintela, Cristina Martinez-Toledo, Ismael Fernández-Miranda, Roberto Serna-Blanco, Virginia Calvo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Neoadjuvant chemoimmunotherapy for non-small cell lung cancer (NSCLC) has improved pathological responses and survival rates compared with chemotherapy alone, leading to Food and Drug Administration (FDA) approval of nivolumab plus chemoth
Externí odkaz:
https://doaj.org/article/536d1ef3434247f3bec7c014036712de
Autor:
Javier Guijarro-Eguinoa, Sara Arjona-Hernandez, Stefan Stewart, Olga Pernia, Pedro Arias, Itsaso Losantos-García, Tania Rubio, Miranda Burdiel, Carlos Rodriguez-Antolin, Patricia Cruz-Castellanos, Oliver Higuera, Alberto M. Borobia, Sonia Rodriguez-Novoa, Javier de Castro-Carpeño, Inmaculada Ibanez de Caceres, Rocio Rosas-Alonso
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9843 (2023)
Platin-based chemotherapy is the standard treatment for patients with non-small cell lung cancer (NSCLC). However, resistance to this therapy is a major obstacle in successful treatment. In this study, we aimed to investigate the impact of several ph
Externí odkaz:
https://doaj.org/article/0e5fbe9e69d44576a788296407aa5978
Autor:
Kamal S. Saini, Begoña de las Heras, Ruth Plummer, Victor Moreno, Marco Romano, Javier de Castro, Philippe Aftimos, Judy Fredriksson, Gouri Shankar Bhattacharyya, Martin Sebastian Olivo, Gaia Schiavon, Kevin Punie, Jesus Garcia-Foncillas, Ernesto Rogata, Richie Pfeiffer, Cecilia Orbegoso, Kenneth Morrison, Giuseppe Curigliano, Lynda Chin, Monika Lamba Saini, Øystein Rekdal, Steven Anderson, Javier Cortes, Manuela Leone, Janet Dancey, Chris Twelves, Ahmad Awada
Publikováno v:
JCO Global Oncology, Vol , Iss 6, Pp 1357-1362 (2020)
Externí odkaz:
https://doaj.org/article/e753a4f9fda043498869674261249653
Autor:
Angel Acosta Rojas, Ana Collazo-Lorduy, Jordi Remon, Ovidio Hernando Requejo, Beatriz Jiménez-Munarriz, María Carmen Rubio Rodríguez, Javier De Castro
Publikováno v:
Case Reports in Oncology, Vol 13, Iss 2, Pp 892-895 (2020)
The incidence of lung cancer during pregnancy is rising due to the high rate of smokers in young women and the late mean age of pregnancy; in addition, considering that the patients are young women with a higher incidence of molecular alterations, mo
Externí odkaz:
https://doaj.org/article/31193891b3cb49fc87d9c983d63d2d63
Autor:
Amelia Insa, Mariano Provencio, Bartomeu Massutí, Margarita Majem, Delvys Rodriguez-Abreu, Manuel Cobo, Manuel Dómine, Joaquín Casal-Rubio, Ernest Nadal, Belén Sierra-Rodero, Alberto Cruz-Bermúdez, Yago Garitaonaindía, Joaquín Mosquera, Alex Martinez-Marti, Javier De Castro Carpeño, Guillermo López Vivanco, Edel Del Barco, Reyes Bernabé Caro, Nuria Viñolas, Isidoro Barneto Aranda, Santiago Viteri, Raquel Laza-Briviesca, Marta Casarrubios, Aránzazu García-Grande, Atocha Romero, Fernando Franco
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/ec8ebeacfddb4e4b8303a2a08265fda0