Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Javier, Valle"'
Autor:
Marco Cavaco, Patrícia Fraga, Javier Valle, Ruben D. M. Silva, Lurdes Gano, João D. G. Correia, David Andreu, Miguel A. R. B. Castanho, Vera Neves
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Blood–brain barrier (BBB) peptide-shuttles (BBBpS) are able to translocate the BBB and reach the brain. Despite the importance of brain targeting in pharmacology, BBBpS are poorly characterized. Currently, their development relies on the e
Externí odkaz:
https://doaj.org/article/ff105247e7514a8eb2dac249aa0d9bfc
Publikováno v:
mSystems, Vol 9, Iss 7 (2024)
ABSTRACT The alarming rise of antibiotic-resistant bacterial infections is driving efforts to develop alternatives to conventional antibiotics. In this context, antimicrobial peptides (AMPs) have emerged as promising candidates for their ability to t
Externí odkaz:
https://doaj.org/article/7441c61a80e14ab89c4305dbb25e0071
Early emergency department discharge for intermediate heart score patients presenting for chest pain
Autor:
Amber Pawlikowski, Elizabeth Hubbard, Joel Krauss, Javier Valle, Jessica Doan, Susanne DeMeester, Bradley Hubbard
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract Study Objective The use of the HEART score to risk stratify patients for short‐term major adverse cardiac events in the emergency department (ED) setting is well established. Although discharge to home for low‐risk HEART score patients i
Externí odkaz:
https://doaj.org/article/160c68ba9a264757a35e9f8cfa5b3460
Autor:
Johana Torralba, Igor de la Arada, Angélica Partida-Hanon, Edurne Rujas, Madalen Arribas, Sara Insausti, Claire Valotteau, Javier Valle, David Andreu, José M. M. Caaveiro, María Angeles Jiménez, Beatriz Apellániz, Lorena Redondo-Morata, José L. Nieva
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The molecular recognition of the carboxy-terminal section of the membrane-proximal external region (C-MPER) of the HIV-1 envelope glycoprotein in membrane mimetics is characterised to help shape continued development of more efficient and stable anti
Externí odkaz:
https://doaj.org/article/45ecf657a3324b21b3025d23f9342963
Autor:
Inés Bouzón-Arnáiz, Yunuen Avalos-Padilla, Arnau Biosca, Omar Caño-Prades, Lucía Román-Álamo, Javier Valle, David Andreu, Diana Moita, Miguel Prudêncio, Elsa M. Arce, Diego Muñoz-Torrero, Xavier Fernàndez-Busquets
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-27 (2022)
Abstract Background By 2016, signs of emergence of Plasmodium falciparum resistance to artemisinin and partner drugs were detected in the Greater Mekong Subregion. Recently, the independent evolution of artemisinin resistance has also been reported i
Externí odkaz:
https://doaj.org/article/e24af2b626fe4416ac7f5ca762819cd1
Autor:
Laura Regalado, Sara Sario, Rafael J. Mendes, Javier Valle, Peta J. Harvey, Cátia Teixeira, Paula Gomes, David Andreu, Conceição Santos
Publikováno v:
Insects, Vol 14, Iss 6, p 533 (2023)
The spotted-wing drosophila (Drosophila suzukii) is a polyphagous pest that causes severe damage and economic losses to soft-skinned fruit production. Current control methods are dominated by inefficient cultural practices and broad-spectrum insectic
Externí odkaz:
https://doaj.org/article/405bad151ef040f3bd52d14aea8267e5
Autor:
Roberto Bello-Madruga, Javier Valle, M. Ángeles Jiménez, Marc Torrent, Vivian Montero-Alejo, David Andreu
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1777 (2023)
β-defensins are one of the most abundant and studied families of antimicrobial peptides (AMPs). Because of their selective toxicity to bacterial membranes and a broad spectrum of microbicidal action, β-defensins are regarded as potential therapeuti
Externí odkaz:
https://doaj.org/article/454a3b78b20f4aafa4ef788cc3c4a0a7
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1349-1358 (2021)
Abstract Proteolytic instability is a critical limitation for peptide‐based products. Although significant efforts are devoted to stabilize sequences against proteases/peptidases in plasma/serum, such approaches tend to be rather empirical, unspeci
Externí odkaz:
https://doaj.org/article/adbdf920d04f4465842e78b226334880
Publikováno v:
Journal of Hymenoptera Research, Vol 78, Iss , Pp 41-56 (2020)
Doryctobracon areolatus (Szépligeti), a solitary endoparasitoid native to the Neotropics, attacks eggs and early instar larvae of Anastrepha fruit flies, and can enter diapause under tropical and subtropical conditions. We aimed to test if biologica
Externí odkaz:
https://doaj.org/article/c3bedca917c74d4e9892920824b63cfb
Autor:
Carlos F Marina, J Guillermo Bond, José Muñoz, Javier Valle, Humberto Quiroz-Martínez, Jorge A Torres-Monzón, Trevor Williams
Publikováno v:
Salud Pública de México, Vol 62, Iss 4, jul-ago, Pp 424-431 (2020)
Objective. To compare the efficacy of three modern larvicides with the organophosphate temephos for control of Aedes aegypti in water tanks in Chiapas. Materials and methods. Trials were performed to compare the efficacy of pyriproxyfen, novaluron, t
Externí odkaz:
https://doaj.org/article/880955fe79954396a0af5f60ddee8337