Zobrazeno 1 - 10
of 385
pro vyhledávání: '"Javier, González Gallego"'
Autor:
Paula Fernández-Palanca, Tania Payo-Serafín, Carolina Méndez-Blanco, Beatriz San-Miguel, María J. Tuñón, Javier González-Gallego, José L. Mauriz
Publikováno v:
Clinical and Molecular Hepatology, Vol 29, Iss 2, Pp 293-319 (2023)
Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers worldwide and is characterized by complex molecular carcinogenesis. Neuropilins (NRPs) NRP1 and NRP2 are the receptors of multiple proteins involved in key signaling pathways
Externí odkaz:
https://doaj.org/article/9a5efbf8caa44fb88a192770aa93373f
Autor:
Sergio Maroto-Izquierdo, Fernando Martín-Rivera, Kazunori Nosaka, Marco Beato, Javier González-Gallego, José A. de Paz
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Eccentric-overload (EO) resistance training emerges as an alternative to more optimally prescribe intensity relative to the force generation capabilities of the eccentric muscle contraction. Given the difficulties to individually prescr
Externí odkaz:
https://doaj.org/article/a325be9e3867471b8f29e510cb0837e1
Autor:
Brisamar Estébanez, Chun-Jung Huang, Marta Rivera-Viloria, Javier González-Gallego, María J. Cuevas
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Childhood obesity is identified as one of the major public health issues to increase the risk for cardiometabolic diseases and related complications in adulthood. The literature has supported inflammation and oxidative stress as the primary underlyin
Externí odkaz:
https://doaj.org/article/0036f9893f134b85a5a1bd10303979b2
Autor:
Rocío Quiroga, Esther Nistal, Brisamar Estébanez, David Porras, María Juárez-Fernández, Susana Martínez-Flórez, María Victoria García-Mediavilla, José A. de Paz, Javier González-Gallego, Sonia Sánchez-Campos, María J. Cuevas
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 7, Pp 1048-1061 (2020)
Childhood obesity: working out for a healthier microbiome Physical fitness regimens could stimulate shifts in gut microbiome composition and metabolism that counteract health risks associated with childhood obesity. This condition can increase the ri
Externí odkaz:
https://doaj.org/article/83f821f8a0184b3d9251d10b2499b4ef
Autor:
Carolina Méndez-Blanco, Paula Fernández-Palanca, Flavia Fondevila, Javier González-Gallego, José L. Mauriz
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Hepatocellular carcinoma (HCC) is a highly recurrent tumor after resection and has been closely related to hypoxia. Hypoxia-inducible factors 1α and 2α (HIF-1α and HIF-2α) have been shown to contribute to tumor progression and therapy
Externí odkaz:
https://doaj.org/article/3d2a41e08d0b4dc8b717300c2f8f0fda
Autor:
Carolina Méndez-Blanco, Flavia Fondevila, Andrés García-Palomo, Javier González-Gallego, José L. Mauriz
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 10, Pp 1-9 (2018)
Liver cancer: overcoming treatment resistance Targeting hypoxia-inducible factors (HIFs), regulatory proteins induced by low oxygen levels, could increase the effectiveness of sorafenib, the only systemic therapy approved for advanced liver cancer. L
Externí odkaz:
https://doaj.org/article/141a6fd1ea72407e969587ff2a31ec12
Autor:
Pedro J. Esteves, Joana Abrantes, Hanna-Mari Baldauf, Lbachir BenMohamed, Yuxing Chen, Neil Christensen, Javier González-Gallego, Lorenzo Giacani, Jiafen Hu, Gilla Kaplan, Oliver T. Keppler, Katherine L. Knight, Xiang-Peng Kong, Dennis K. Lanning, Jacques Le Pendu, Ana Lemos de Matos, Jia Liu, Shuying Liu, Ana M. Lopes, Shan Lu, Sheila Lukehart, Yukari C. Manabe, Fabiana Neves, Grant McFadden, Ruimin Pan, Xuwen Peng, Patricia de Sousa-Pereira, Ana Pinheiro, Masmudur Rahman, Natalie Ruvoën-Clouet, Selvakumar Subbian, Maria Jesús Tuñón, Wessel van der Loo, Michael Vaine, Laura E. Via, Shixia Wang, Rose Mage
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 5, Pp 1-10 (2018)
Infectious disease: A leap forward for disease models Rabbits offer a powerful complement to rodents as a model for studying human immunology, disease pathology, and responses to infectious disease. A review from Pedro Esteves at the University of Po
Externí odkaz:
https://doaj.org/article/291d4ead9ccb4771a09c51a1a83754c4
Autor:
Paula Fernández-Palanca, Tania Payo-Serafín, Beatriz San-Miguel, Carolina Méndez-Blanco, María J. Tuñón, Javier González-Gallego, José L. Mauriz
Publikováno v:
Acta Pharmacologica Sinica. 44:1066-1082
Despite pharmacological advances such as lenvatinib approval, therapeutic failure of hepatocellular carcinoma (HCC) remains a big challenge due to the complexity of its underlying molecular mechanisms. Neuropilin-1 (NRP1) is a co-receptor involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d8da5a30101f5456a87d99e25bb07a
https://doi.org/10.1038/s41401-022-01021-2
https://doi.org/10.1038/s41401-022-01021-2
Autor:
María Juárez-Fernández, David Porras, Petar Petrov, Sara Román-Sagüillo, María Victoria García-Mediavilla, Polina Soluyanova, Susana Martínez-Flórez, Javier González-Gallego, Esther Nistal, Ramiro Jover, Sonia Sánchez-Campos
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 2001 (2021)
Gut microbiota plays a key role in obesity and non-alcoholic fatty liver disease (NAFLD), so synbiotics could be a therapeutic alternative. We aim to evaluate a nutritional intervention together with the administration of the bacteria Akkermansia muc
Externí odkaz:
https://doaj.org/article/fca26b4c9112454b9cddead68a19808d
Autor:
Jiménez-Pavón, Brisamar Estébanez, Francisco J. Amaro-Gahete, Cristina Gil-González, Javier González-Gallego, María J. Cuevas, David
Publikováno v:
Nutrients; Volume 15; Issue 13; Pages: 3069
Exosome release varies depending on the physiological state of the cell, so they could play a fundamental role in obesity, the biggest pandemic in today’s societies. The beneficial effects that physical activity has both on weight and cardiovascula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::e7cc144ea2f6304ac9fdfa7a6a429da1