Matching-Adjusted Indirect Comparisons in the assessment of hemato-oncological drugs

Autor: Francisco Javier Parrondo-García, José Manuel Martínez-Sesmero, Javier De Castro-Carpeño, Araceli López-de las Heras, Alonso Fernández-Nistal

Publikováno v: Farmacia Hospitalaria, Vol 45, Iss 2, Pp 55-60 (2021)

Objective: Matching-Adjusted Indirect Comparison is a methodology that has been developed to assess new treatments vs alternatives when a direct comparison is not available through a randomized controlled trial. These comparisons are of particular in

Externí odkaz: https://doaj.org/article/91040d96b5394780825a35f9c74bf415

Blood biomarkers associated to complete pathological response on NSCLC patients treated with neoadjuvant chemoimmunotherapy included in NADIM clinical trial

Autor: Raquel Laza‐Briviesca, Alberto Cruz‐Bermúdez, Ernest Nadal, Amelia Insa, María del Rosario García‐Campelo, Gerardo Huidobro, Manuel Dómine, Margarita Majem, Delvys Rodríguez‐Abreu, Alex Martínez‐Martí, Javier De Castro Carpeño, Manuel Cobo, Guillermo López Vivanco, Edel Del Barco, Reyes Bernabé Caro, Nuria Viñolas, Isidoro Barneto Aranda, Santiago Viteri, Bartomeu Massuti, Marta Casarrubios, Belén Sierra‐Rodero, Carlos Tarín, Aránzazu García‐Grande, Cara Haymaker, Ignacio I. Wistuba, Atocha Romero, Fernando Franco, Mariano Provencio

Publikováno v: Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)

Abstract Background Immunotherapy is being tested in early‐stage non‐small cell lung cancer (NSCLC), and achieving higher rates of complete pathological responses (CPR) as compared to standard of care. Early identification of CPR patients has vit

Externí odkaz: https://doaj.org/article/0ad46e49a0734ef1b5f505f363328cb9

Overall Survival and Biomarker Analysis of Neoadjuvant Nivolumab Plus Chemotherapy in Operable Stage IIIA Non–Small-Cell Lung Cancer (NADIM phase II trial)

Autor: Mariano Provencio, Roberto Serna-Blasco, Ernest Nadal, Amelia Insa, M. Rosario García-Campelo, Joaquín Casal Rubio, Manuel Dómine, Margarita Majem, Delvys Rodríguez-Abreu, Alex Martínez-Martí, Javier De Castro Carpeño, Manuel Cobo, Guillermo López Vivanco, Edel Del Barco, Reyes Bernabé Caro, Nuria Viñolas, Isidoro Barneto Aranda, Santiago Viteri, Eva Pereira, Ana Royuela, Virginia Calvo, Javier Martín-López, Francisco García-García, Marta Casarrubios, Fernando Franco, Estela Sánchez-Herrero, Bartomeu Massuti, Alberto Cruz-Bermúdez, Atocha Romero

Publikováno v: JOURNAL OF CLINICAL ONCOLOGY
r-CIPF. Repositorio Institucional Producción Científica del Centro de Investigación Principe Felipe (CIPF)
Universitat Rovira i virgili (URV)
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Scientia

PURPOSE Neoadjuvant chemotherapy plus nivolumab has been shown to be effective in resectable non–small-cell lung cancer (NSCLC) in the NADIM trial (ClinicalTrials.gov identifier: NCT03081689 ). The 3-year overall survival (OS) and circulating tumor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea7330b9d5f399beeb1fe0adeeb286f
https://doi.org/10.1200/jco.21.02660

Prognostic Impact of Dihydropyrimidine Dehydrogenase Germline Variants in Unresectable Non-Small Cell Lung Cancer Patients Treated with Platin-Based Chemotherapy

Autor: Rosas-Alonso, Javier Guijarro-Eguinoa, Sara Arjona-Hernandez, Stefan Stewart, Olga Pernia, Pedro Arias, Itsaso Losantos-García, Tania Rubio, Miranda Burdiel, Carlos Rodriguez-Antolin, Patricia Cruz-Castellanos, Oliver Higuera, Alberto M. Borobia, Sonia Rodriguez-Novoa, Javier de Castro-Carpeño, Inmaculada Ibanez de Caceres, Rocio

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9843

Platin-based chemotherapy is the standard treatment for patients with non-small cell lung cancer (NSCLC). However, resistance to this therapy is a major obstacle in successful treatment. In this study, we aimed to investigate the impact of several ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::f791954e85732798038e1482e4c4365d

Matching-Adjusted Indirect Comparisons in the assessment of hemato-oncological drugs

Autor: José Manuel, Martínez-Sesmero, Javier, De Castro-Carpeño, Araceli, López-de Las Heras, Alonso, Fernández-Nistal, Francisco Javier, Parrondo-García

Publikováno v: Farmacia Hospitalaria, Vol 45, Iss 2, Pp 55-60 (2021)

Matching-Adjusted Indirect Comparison is a methodology that has been developed to assess new treatments vs alternatives when a direct comparison is not available through a randomized controlled trial. These comparisons are of particular interest in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2a09599c8d621fe1b3c708e1f8d3d257
http://www.aulamedica.es/fh/pdf/11443.pdf