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pro vyhledávání: '"Javier, Aguirre Rivera"'
Autor:
Anton Sabantsev, Guanzhong Mao, Javier Aguirre Rivera, Mikhail Panfilov, Anatolii Arseniev, Oanh Ho, Mikhail Khodorkovskiy, Sebastian Deindl
Publikováno v:
Nature Chemical Biology
Many essential processes in the cell depend on proteins that use nucleoside triphosphates (NTPs). Methods that directly monitor the often-complex dynamics of these proteins at the single-molecule level have helped to uncover their mechanisms of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656721e95e5f8b7c2aa3670069db1cc9
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-493272
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-493272
Autor:
Javier, Aguirre Rivera, Jimmy, Larsson, Ivan L, Volkov, A Carolin, Seefeldt, Suparna, Sanyal, Magnus, Johansson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance To address the public health challenges caused by the spread of antibiotic resistance, it is critical to enhance our understanding of the mechanisms of action of these compounds. In the present study, we use superresolved single-molecule
Direct Measurements of Erythromycin’s Effect on Protein Synthesis Kinetics in Living Bacterial Cells
Publikováno v:
Journal of Molecular Biology. 433:166942
Macrolide antibiotics, such as erythromycin, bind to the nascent peptide exit tunnel (NPET) of the bacterial ribosome and modulate protein synthesis depending on the nascent peptide sequence. Whereas in vitro biochemical and structural methods have b
Autor:
Javier Aguirre Rivera, Ka-Weng Ieong, Ivan L. Volkov, Martin Lindén, Johan Elf, Magnus Johansson, Mikhail Metelev
Publikováno v:
Nature chemical biology
Our ability to directly relate results from test-tube biochemical experiments to the kinetics in living cells is very limited. Here we present experimental and analytical tools to directly study the kinetics of fast biochemical reactions in live cell