Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.

Autor: Dobrindt K; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Hoagland DA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Seah C; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Kassim B; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029., O'Shea CP; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Iskhakova M; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Fernando MB; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Deans PJM; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Powell SK; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Javidfar B; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Murphy A; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Peter C; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Møeller R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA.; Graduate School of Biomedical Science, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Garcia MF; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Kimura M; Division of Gastroenterology, Hepatology and Nutrition; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center; Center for Stem Cell and Organoid Medicine (CuSTOM); Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States; Institute of Research, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Iwasawa K; Division of Gastroenterology, Hepatology and Nutrition; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center; Center for Stem Cell and Organoid Medicine (CuSTOM); Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States; Institute of Research, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Crary J; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Kotton DN; Center for Regenerative Medicine of Boston University and Boston Medical Center, Pulmonary Center and Department of Medicine, Boston University School of Medicine, Boston, MA., Takebe T; Division of Gastroenterology, Hepatology and Nutrition; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center; Center for Stem Cell and Organoid Medicine (CuSTOM); Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States; Institute of Research, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Huckins LM; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Mental Illness Research, Education and Clinical Centers, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY 10468, USA., tenOever BR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1603, New York, NY 10029, USA., Akbarian S; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029., Brennand KJ; Pamela Sklar Division of Psychiatric Genomics, Department of Genetics and Genomics, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2020 Sep 21. Date of Electronic Publication: 2020 Sep 21.