Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Javad Tavakkoly-Bazzaz"'
Autor:
Pardis Rahimi Salekdeh, Leila Ma’mani, Javad Tavakkoly-Bazzaz, Hossein Mousavi, Mohammad Hossein Modarressi, Ghasem Hosseini Salekdeh
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background There is a great interest in the efficient intracellular delivery of Cas9-sgRNA ribonucleoprotein complex (RNP) and its possible applications for in vivo CRISPR-based gene editing. In this study, a nanoporous mediated gene-editing
Externí odkaz:
https://doaj.org/article/2bb08f75949c4d7892b6242945ff3bb5
Publikováno v:
Tehran University Medical Journal, Vol 76, Iss 8, Pp 509-516 (2018)
Cancer immunotherapy refers to any intervention that leverages the immune system to eliminate a malignancy. Successful cancer immunotherapies generate an anti-cancer response that is systemic, specific, and durable and overcome to the primary limitat
Externí odkaz:
https://doaj.org/article/541368cc83a1440f8e1a56bc861851b9
Autor:
Hossein Pashaiefar, Marjan Yaghmaie, Javad Tavakkoly-Bazzaz, Seyed Hamidollah Ghaffari, Kamran Alimoghaddam, Izadi Pantea, Ardeshir Ghavamzadeh
Publikováno v:
Cell Journal, Vol 20, Iss 2, Pp 204-210 (2018)
Objective Chromosomal translocations are among the most common mutational events in cancer development, especially in hematologic malignancies. However, the precise molecular mechanism of these events is still not clear. It has been recently shown t
Externí odkaz:
https://doaj.org/article/c1be81d1c9c54ba4b6f4acecdcc59b54
Autor:
Majid Momeny, Ghazaleh Zarrinrad, Farima Moghaddaskho, Arash Poursheikhani, Ghazaleh Sankanian, Azam Zaghal, Shahab Mirshahvaladi, Fatemeh Esmaeili, Haniyeh Eyvani, Farinaz Barghi, Zahra Sabourinejad, Zivar Alishahi, Hassan Yousefi, Reza Ghasemi, Leila Dardaei, Davood Bashash, Bahram Chahardouli, Ahmad R. Dehpour, Javad Tavakkoly-Bazzaz, Kamran Alimoghaddam, Ardeshir Ghavamzadeh, Seyed H. Ghaffari
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Epithelial ovarian cancer (EOC) is the most lethal gynaecological malignancy worldwide. Development of chemoresistance and peritoneal dissemination of EOC cells are the major reasons for low survival rate. Targeting signal transduction pathw
Externí odkaz:
https://doaj.org/article/371260993ffc4717abe454c0586b4782
Autor:
Golnaz Khakpour, Mehrdad Noruzinia, Pantea Izadi, Fatemeh Karami, Mohammad Ahmadvand, Ramin Heshmat, Mahsa M Amoli, Javad Tavakkoly-Bazzaz
Publikováno v:
Tumor Biology, Vol 39 (2017)
Critical roles of epigenomic alterations in the pathogenesis of breast cancer have recently seized great attentions toward finding epimarkers in either non-invasive or semi-non-invasive samples as well as peripheral blood. In this way, methylated DNA
Externí odkaz:
https://doaj.org/article/a77c3ebb644e4f849dea710aa8e906e7
Autor:
Farima Moghaddaskho, Haniyeh Eyvani, Mohsen Ghadami, Javad Tavakkoly-Bazzaz, Kamran Alimoghaddam, Ardeshir Ghavamzadeh, Seyed H Ghaffari
Publikováno v:
Tumor Biology, Vol 39 (2017)
Arsenic trioxide (As 2 O 3 ) has been used clinically as an anti-tumor agent. Its mechanisms are mostly considered to be the induction of apoptosis and cell cycle arrest. However, the detailed molecular mechanisms of its anti-cancer action through ce
Externí odkaz:
https://doaj.org/article/31f5dcbee7444c3ebdf34038b14195c1
Autor:
Mahsa M. Amoli, Parvin Amiri, Javad Tavakkoly-Bazzaz, Elham Charmchi, Jila Hafeziyeh, Mohammad Keramatipour, Maryam Abiri, Shirin Hasani Ranjbar, Bagher Larijani
Publikováno v:
Genetics and Molecular Biology, Vol 33, Iss 3, Pp 449-451 (2010)
The transcription factor 7-like 2 gene (TCF7L2) rs7903146 T allele is constantly associated with Type 2 diabetes in various populations and ethnic groups. Nevertheless, this has not been observed in two studies involving Arab populations. The aim of
Externí odkaz:
https://doaj.org/article/bd370baf8f74497594604639f248b869
Autor:
Maedeh Arabpour, Sepideh Mehrpour Layeghi, Keivan Majidzadeh-A, Javad Tavakkoly Bazzaz, Ali Mamivand, Mohammad Mehdi Naghizadeh, Abbas Shakoori
Publikováno v:
Biochemistry and Biophysics Reports, Vol 35, Iss , Pp 101531- (2023)
Background: Luminal A and B subtypes of breast cancer (BC) comprises up to 70% of all BC patients. LncRNAs can affect many biological and pathological processes, and dysregulation of them is related to human cancers. The potential role of lncRNA LINC
Externí odkaz:
https://doaj.org/article/152f6a3247014dbba0f26d47c3739e52
Publikováno v:
Journal of Research in Applied and Basic Medical Sciences, Vol 6, Iss 1, Pp 14-17 (2020)
Carriers of structural chromosomal rearrangements such as Robertsonian or reciprocal translocations have an increased risk of spontaneous abortion and producing offspring with genetic abnormalities. Robertsonian translocations are present in 0.1% of
Externí odkaz:
https://doaj.org/article/5ad80fa027404f5ea25f8f56f7ab2bb2
Autor:
Javad Tavakkoly Bazzaz, Sepideh Mehrpour Layeghi, Maedeh Arabpour, Abbas Shakoori, Mohammad Mehdi Naghizadeh, Keivan Majidzadeh-A
Publikováno v:
Human Cell. 34:1227-1243
Numerous studies have demonstrated that lncRNAs participate in regulatory networks of different cancers. Dysregulation of various lncRNAs such as DUXAP8, LINC00963, and FOXD2-AS1 has been reported in the development of various cancers. The aim of thi