Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Javad Fahanik‐Babaei"'
Autor:
Amir Barzegar Behrooz, Mohamad-Reza Aghanoori, Maryam Nazari, Hamid Latifi-Navid, Fatemeh Vosoughian, Mojdeh Anjomani, Jabar Lotfi, Abolhassan Ahmadiani, Afsaneh Eliassi, Fatemeh Nabavizadeh, Elham Soleimani, Saeid Ghavami, Fariba Khodagholi, Javad Fahanik-Babaei
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Alzheimer’s disease (AD) is the most prevalent type of dementia. Its causes are not fully understood, but it is now known that factors like mitochondrial dysfunction, oxidative stress, and compromised ion channels contribute to its onset a
Externí odkaz:
https://doaj.org/article/52d9a9476105415ba6e87daf8b2f1016
Autor:
Sahra Jalalkamali, Mohsen Ghahremani, Vida Jashn, Negin Sadat Lajevardi, Sevda Mahdipoor Koloor, Seyede Zohreh Jazaeri, Javad Fahanik-babaei
Publikováno v:
IBRO Neuroscience Reports, Vol 17, Iss , Pp 372-381 (2024)
Introduction: Processes that generate systemic inflammation are strongly associated with neurodegenerative diseases. This study aimed to explore the potential anti-oxidative and anti-inflammatory effects of fasudil and its role in modulating aquapori
Externí odkaz:
https://doaj.org/article/fe05a228c1844342b896adb850158d03
Autor:
Morteza Nazari-Serenjeh, Tourandokht Baluchnejadmojarad, Masoud Hatami-Morassa, Javad Fahanik-Babaei, Soraya Mehrabi, Mahsa Tashakori-Miyanroudi, Samira Ramazi, Seyed-Mahdi Mohamadi-Zarch, Davood Nourabadi, Mehrdad Roghani
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25564- (2024)
Alzheimer's disease (AD) is acknowledged as the main causative factor of dementia that affects millions of people around the world and is increasing at increasing pace. Okadaic acid (OA) is a toxic compound with ability to inhibit protein phosphatase
Externí odkaz:
https://doaj.org/article/c6bddcfb9dde46af823d868b73806230
Autor:
Fateme Binayi, Javad Fahanik-Babaei, Mina Salimi, Farzaneh Eskandari, Mohammad Sahraei, Ali Ghorbani Ranjbary, Rasoul Ghasemi, Mehdi Hedayati, Fariba Khodagholi, Afsaneh Eliassi, Homeira Zardooz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Endoplasmic reticulum (ER) stress is involved in the development of glucose homeostasis impairment. When ER stress occurs, the unfolded protein response (UPR) is activated to cope with it. One of the UPR components is WFS1 (Wolfram syndrome
Externí odkaz:
https://doaj.org/article/e9b7e767bdfc4c35bdd262987741d248
Autor:
Mina Salimi, Farzaneh Eskandari, Fateme Binayi, Afsaneh Eliassi, Hossein Ghanbarian, Mehdi Hedayati, Javad Fahanik-babaei, Mohamad Eftekhary, Rana Keyhanmanesh, Homeira Zardooz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Exposure to perinatal (prenatal and/or postnatal) stress is considered as a risk factor for metabolic disorders in later life. Accordingly, this study aimed to investigate the perinatal stress effects on the pancreatic endoplasmic reticulum
Externí odkaz:
https://doaj.org/article/16441d4815474d3d94884296b70ffb04
Autor:
Sobhan Haghani, Nida Jamali-Raeufy, Motahareh Zeinivand, Soraya Mehrabi, Leila Aryan, Javad Fahanik-Babaei
Publikováno v:
Basic and Clinical Neuroscience, Vol 12, Iss 6, Pp 805-816 (2021)
Introduction: Although pharmacotherapy is the most common treatment for epilepsy, proper seizure control is not achieved with current medications. This study evaluated the protective effects of the Hepatocyte Growth Factor (HGF) in a rat model of Tem
Externí odkaz:
https://doaj.org/article/f7acc44520a24f938b40e97baaee91d9
Autor:
Javad Fahanik‐Babaei, Mohsen Sedighi, Soraya Mehrabi, Omid Pournik, Abbas Sheikh Taheri, Leila Kamalzadeh, Mahsa Zarei, Mehrdad Roghani, Fereshteh Golab, Mostafa Almasi, Afshin Etezadi, Siamak Afshin‐Majd, Seyed Kazem Malakouti, Majid Rajabi, Mehdi Moghaddasi, Gholamreza Hajati, Fatemeh Golmohammadi Khamne, Arzhang Jafari, Alireza Amanollahi, Tourandokht Baluchnejadmojarad
Publikováno v:
Health Science Reports, Vol 5, Iss 6, Pp n/a-n/a (2022)
Abstract Background and Aims Alzheimer's disease (AD) is the main cause of dementia and over the 55 million people live with dementia worldwide. We aimed to establish the first database called the Iranian Alzheimer's Disease Registry to create a powe
Externí odkaz:
https://doaj.org/article/1cb7cab827d444d08ab95df2fbd7566a
Publikováno v:
Basic and Clinical Neuroscience, Vol 11, Iss 4, Pp 517-524 (2020)
Introduction: Synaptic plasticity is inappropriately affected by neurodegenerative diseases, including Alzheimer Disease (AD). In this study, we examined the effect of intrahippocampal amyloid-beta (Aβ1-40) on dentate gyrus Long-term Potentiation (L
Externí odkaz:
https://doaj.org/article/08757a1f71a245be9dfe79265bd5e121
Publikováno v:
Acta Medica Iranica, Vol 56, Iss 10 (2019)
- Intrahippocampal amyloid β (Aβ) negatively affects synaptic plasticity with subsequent impairment of learning and memory. Trigonelline is an alkaloid commonly found in fenugreek seeds and coffee beans with neuroprotective property and a promising
Externí odkaz:
https://doaj.org/article/c79e87df6c924bd985538f6f798a3b87
Autor:
Sajjad Salari, Maedeh Ghasemi, Javad Fahanik-Babaei, Reza Saghiri, Remy Sauve, Afsaneh Eliassi
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125798 (2015)
We report in a previous study the presence of a large conductance K+ channel in the membrane of rough endoplasmic reticulum (RER) from rat hepatocytes incorporated into lipid bilayers. Channel activity in this case was found to decrease in presence o
Externí odkaz:
https://doaj.org/article/1e5cb01a9b33418f882c5a057aeda9d8