Výsledky vyhledávání - "Jauset González, Toni"

Inhibiting Myc in cancer using Omomyc. From defining the fundamental mechanism of action to its pharmacological application

Autor: Jauset González, Toni

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

Identifying and targeting cancer cell components that play non-degenerate and non-redundant functions within cancers could lead to the development of more effective therapies. Myc is considered a prime example of such a target, and has been character

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::3976f0eb7495873124b5ce1b9958c6d3
http://hdl.handle.net/10803/662770

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Ibrutinib repurposing : from B-cell malignancies to solid tumors

Autor: Massó Vallés, Daniel, Jauset González, Toni, Soucek, Laura, Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Oncoscience

Ibrutinib (Imbruvica®, also known as PCI-32765) is a first-in-class, irreversible small-molecule inhibitor of Bruton's Tyrosine Kinase (BTK) that binds covalently to cysteine C481 within the ATP-binding pocket. Since BTK is a Tec family non-receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2d1001b7ceed593d049c8c988e8271
https://ddd.uab.cat/record/185945

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