Controlling gene expression with deep generative design of regulatory DNA.

Autor: Zrimec J; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden. jan.zrimec@nib.si.; Department of Biotechnology and Systems Biology, National Institute of Biology, Večna pot 111, SI1000, Ljubljana, Slovenia. jan.zrimec@nib.si., Fu X; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden., Muhammad AS; Department of Computer Science and Engineering, Chalmers University of Technology, Rännvägen 6, SE41296, Gothenburg, Sweden., Skrekas C; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden., Jauniskis V; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden.; Biomatter Designs, Zirmunu st. 139A, LT09120, Vilnius, Lithuania., Speicher NK; Department of Computer Science and Engineering, Chalmers University of Technology, Rännvägen 6, SE41296, Gothenburg, Sweden., Börlin CS; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden.; BioInnovation Institute, Ole Maaloes Vej 3, DK2200, Copenhagen N, Denmark., Verendel V; Department of Computer Science and Engineering, Chalmers University of Technology, Rännvägen 6, SE41296, Gothenburg, Sweden., Chehreghani MH; Department of Computer Science and Engineering, Chalmers University of Technology, Rännvägen 6, SE41296, Gothenburg, Sweden., Dubhashi D; Department of Computer Science and Engineering, Chalmers University of Technology, Rännvägen 6, SE41296, Gothenburg, Sweden., Siewers V; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden., David F; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden., Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden.; BioInnovation Institute, Ole Maaloes Vej 3, DK2200, Copenhagen N, Denmark., Zelezniak A; Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE41296, Gothenburg, Sweden. aleksej.zelezniak@chalmers.se.; Institute of Biotechnology, Life Sciences Centre, Vilnius University, Sauletekio al. 7, LT10257, Vilnius, Lithuania. aleksej.zelezniak@chalmers.se.; Randall Centre for Cell & Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, SE1 1UL, London, UK. aleksej.zelezniak@chalmers.se.

Publikováno v: Nature communications [Nat Commun] 2022 Aug 30; Vol. 13 (1), pp. 5099. Date of Electronic Publication: 2022 Aug 30.

Drug Discovery in the Age of Artificial Intelligence: Transformative Target-Based Approaches.

Autor: Patne, Akshata Yashwant^1,2 (AUTHOR) apatne@usf.edu, Dhulipala, Sai Madhav³ (AUTHOR) saimadhavdhulipala@usf.edu, Lawless, William^3,4 (AUTHOR) wlawless@usf.edu, Prakash, Satya⁵ (AUTHOR) satya.prakash@mcgill.ca, Mohapatra, Shyam S.^1,2,4 (AUTHOR) smohapat@usf.edu, Mohapatra, Subhra^1,2,3,4 (AUTHOR) smohapat@usf.edu

Publikováno v: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12233. 16p.

Deep learning in template-free de novo biosynthetic pathway design of natural products.

Autor: Xie, Xueying^1,2 (AUTHOR), Gui, Lin³ (AUTHOR), Qiao, Baixue^1,2 (AUTHOR), Wang, Guohua³ (AUTHOR), Huang, Shan⁴ (AUTHOR) hmuhuangshan@163.com, Zhao, Yuming³ (AUTHOR) hmuhuangshan@163.com, Sun, Shanwen^1,2 (AUTHOR) hmuhuangshan@163.com

Publikováno v: Briefings in Bioinformatics. Nov2024, Vol. 25 Issue 6, p1-19. 19p.

Research on Bitter Peptides in the Field of Bioinformatics: A Comprehensive Review.

Autor: Liu, Shanghua¹ (AUTHOR) 202321140418@std.uestc.edu.cn, Shi, Tianyu¹ (AUTHOR), Yu, Junwen¹ (AUTHOR), Li, Rui¹ (AUTHOR), Lin, Hao¹ (AUTHOR) hlin@uestc.edu.cn, Deng, Kejun¹ (AUTHOR) hlin@uestc.edu.cn

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p9844. 23p.

AI-Assisted Rational Design and Activity Prediction of Biological Elements for Optimizing Transcription-Factor-Based Biosensors.

Autor: Ding, Nana^1,2 (AUTHOR) dingnana911128@163.com, Yuan, Zenan^1,2 (AUTHOR), Ma, Zheng³ (AUTHOR) mazheng520@163.com, Wu, Yefei⁴ (AUTHOR) yefei0906@163.com, Yin, Lianghong^1,2 (AUTHOR) dingnana911128@163.com

Publikováno v: Molecules. Aug2024, Vol. 29 Issue 15, p3512. 24p.