Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Jaume Amengual"'
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102007- (2024)
Objective: Carotenoids are lipophilic plant molecules with antioxidant properties. Some carotenoids such as β-carotene also serve as vitamin A precursors, playing a key role in human health. Carotenoids are transported in lipoproteins with other lip
Externí odkaz:
https://doaj.org/article/134aa0c05ecd4e63b2d5be283306ec9a
Autor:
Haizhen Wang, Cyrus Nikain, Konstantinos I. Fortounas, Jaume Amengual, Ozlem Tufanli, Maxwell La Forest, Yong Yu, Meng C. Wang, Russell Watts, Richard Lehner, Yunping Qiu, Min Cai, Irwin J. Kurland, Ira J. Goldberg, Sujith Rajan, M. Mahmood Hussain, Jeffrey L. Brodsky, Edward A. Fisher
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102048- (2024)
Objective: Triglycerides (TGs) associate with apolipoprotein B100 (apoB100) to form very low density lipoproteins (VLDLs) in the liver. The repertoire of factors that facilitate this association is incompletely understood. FITM2, an integral endoplas
Externí odkaz:
https://doaj.org/article/98f69e2137b44289b6b69aa78d3204eb
Autor:
Patrick McQueen, Donald Molina, Ivan Pinos, Samuel Krug, Anna J. Taylor, Michael R. LaFrano, Maureen A. Kane, Jaume Amengual
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100507- (2024)
Finasteride is commonly prescribed to treat benign prostate hyperplasia and male-pattern baldness in cis men and, more recently, trans individuals. However, the effect of finasteride on cardiovascular disease remains elusive. We evaluated the role of
Externí odkaz:
https://doaj.org/article/54e13fbc21f84c7480a066af032f0e6f
Autor:
Anthony P. Miller, Dámaso Hornero-Méndez, Sepalika Bandara, Obdulia Parra-Rivero, M. Carmen Limón, Johannes von Lintig, Javier Avalos, Jaume Amengual
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Various species of ascomycete fungi synthesize the carboxylic carotenoid neurosporaxanthin. The unique chemical structure of this xanthophyll reveals that: (1) Its carboxylic end and shorter length increase the polarity of neurosporaxanthin
Externí odkaz:
https://doaj.org/article/e316ef235a0c4bf592f67e52d34fdd18
Autor:
Ivan Pinos, Johana Coronel, Asma'a Albakri, Amparo Blanco, Patrick McQueen, Donald Molina, JaeYoung Sim, Edward A Fisher, Jaume Amengual
Publikováno v:
eLife, Vol 12 (2024)
β-Carotene oxygenase 1 (BCO1) catalyzes the cleavage of β-carotene to form vitamin A. Besides its role in vision, vitamin A regulates the expression of genes involved in lipid metabolism and immune cell differentiation. BCO1 activity is associated
Externí odkaz:
https://doaj.org/article/592da35d226e4012b20799dc36c9152a
Autor:
Laura Senatus, Lander Egaña-Gorroño, Raquel López-Díez, Sonia Bergaya, Juan Francisco Aranda, Jaume Amengual, Lakshmi Arivazhagan, Michaele B. Manigrasso, Gautham Yepuri, Ramesh Nimma, Kaamashri N. Mangar, Rollanda Bernadin, Boyan Zhou, Paul F. Gugger, Huilin Li, Richard A. Friedman, Neil D. Theise, Alexander Shekhtman, Edward A. Fisher, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Male and female mice deficient in DIAPH1 are protected from the development of experimental atherosclerosis and display reduced cholesterol levels; these changes are linked to the regulation of SREBP1 subcellular localization.
Externí odkaz:
https://doaj.org/article/3b884c6d0ad746b0ae3401514cb0c693
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101640- (2022)
Objective: The β-carotene oxygenase 1 (BCO1) is the enzyme responsible for the cleavage of β-carotene to retinal, the first intermediate in vitamin A formation. Preclinical studies suggest that BCO1 expression is required for dietary β-carotene to
Externí odkaz:
https://doaj.org/article/f8c297f263e84e5d918d63e56fa46bc8
Autor:
Felix Zhou, Xiaoyun Wu, Ivan Pinos, Benjamin M. Abraham, Tessa J. Barrett, Johannes von Lintig, Edward A. Fisher, Jaume Amengual
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 11, Pp 1491-1503 (2020)
Atherosclerosis is characterized by the pathological accumulation of cholesterol-laden macrophages in the arterial wall. Atherosclerosis is also the main underlying cause of CVDs, and its development is largely driven by elevated plasma cholesterol.
Externí odkaz:
https://doaj.org/article/bfe34f46c7c946cc8eae3ff815a66901
Autor:
Jaume Amengual, Francisco J. García-Carrizo, Andrea Arreguín, Hana Mušinović, Nuria Granados, Andreu Palou, M. Luisa Bonet, Joan Ribot
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 187-202 (2018)
Background/Aims: All-trans retinoic acid (ATRA) has protective effects against obesity and metabolic syndrome. We here aimed to gain further insight into the interaction of ATRA with skeletal muscle metabolism and secretory activity as important play
Externí odkaz:
https://doaj.org/article/93da63162bb0472280750deff20b6418
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 342 (2021)
Lycopene is a non-provitamin A carotenoid that exhibits several health benefits. Epidemiological data support a correlation between lycopene intake and the attenuation of several chronic diseases, including certain types of cancers and cardiovascular
Externí odkaz:
https://doaj.org/article/9bf0832e3e794456834a9e28c201c1a4