Zobrazeno 1 - 10
of 611
pro vyhledávání: '"Jau-Shyong Hong"'
Autor:
Tzu-Yun Wang, Eddie Feng-Ju Weng, Yun-Chen Hsu, Lu-Ping Shiu, Teng-Wei Huang, Hsuan-Cheng Wu, Jau-Shyong Hong, Shao-Ming Wang
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract There is an intrinsic relationship between psychiatric disorders and neuroinflammation, including bipolar disorder. Ouabain, an inhibitor of Na+/K+-ATPase, has been implicated in the mouse model with manic-like behavior. However, the molecul
Externí odkaz:
https://doaj.org/article/e4cc94f0c5804be8ab88ecb27f002db7
Autor:
Qinghui Wang, Zhengzheng Ruan, Lu Jing, Ziyang Guo, Xiaomeng Zhang, Jianing Liu, Lu Tian, Wei Sun, Sheng Song, Jau-Shyong Hong, Yen-Yu Ian Shih, Liyan Hou, Qingshan Wang
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 266, Iss , Pp 115550- (2023)
Microglia-mediated chronic neuroinflammation has been associated with cognitive decline induced by rotenone, a well-known neurotoxic pesticide used in agriculture. However, the mechanisms remain unclear. This work aimed to elucidate the role of compl
Externí odkaz:
https://doaj.org/article/e4cf199f47564cf592eea8a94822c71c
Autor:
Sheng Song, Dezhen Tu, Chengbo Meng, Jie Liu, Belinda Wilson, Qingshan Wang, Yen-Yu Ian Shih, Hui-Ming Gao, Jau-Shyong Hong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Clinical and pathological evidence revealed that α-synuclein (α-syn) pathology seen in PD patients starts in the gut and spreads via anatomically connected structures from the gut to the brain. Our previous study demonstrated that depletion of cent
Externí odkaz:
https://doaj.org/article/de050ff19a674fdcbf95fce7b617833d
Autor:
Dongdong Zhang, Sheng Li, Liyan Hou, Lu Jing, Zhengzheng Ruan, Bingjie Peng, Xiaomeng Zhang, Jau-Shyong Hong, Jie Zhao, Qingshan Wang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Cognitive decline occurs frequently in Parkinson’s disease (PD), which greatly decreases the quality of life of patients. However, the mechanisms remain to be investigated. Neuroinflammation mediated by overactivated microglia i
Externí odkaz:
https://doaj.org/article/edf8aebd8fb045669e5bb7d7e79239ce
Autor:
Sawako Shindo, Shih-Heng Chen, Saki Gotoh, Kosuke Yokobori, Hao Hu, Manas Ray, Rick Moore, Kiyoshi Nagata, Jennifer Martinez, Jau-Shyong Hong, Masahiko Negishi
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Estrogen receptor α (ERα) has been suggested to regulate anti-inflammatory signaling in brain microglia, the only resident immune cells in the brain. ERα conserves the phosphorylation motif at Ser216 within the DNA binding doma
Externí odkaz:
https://doaj.org/article/f47bed05def941a5a8f9466a17d42c03
Autor:
Sheng-Yu Lee, Tzu-Yun Wang, Shiou-Lan Chen, Yun-Hsuan Chang, Po-See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I-Hui Lee, Kao-Ching Chen, Yen-Kuang Yang, Jau-Shyong Hong, Ru-Band Lu
Publikováno v:
International Journal of Bipolar Disorders, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Background The aim of this study is to determine whether adding combination of agents with anti-inflammatory and neurotrophic effects is more efficacious than mood stabilizer alone in improving clinical symptoms, plasma brain-derived neurotr
Externí odkaz:
https://doaj.org/article/fc0c8e5bfbd642cabdea237631700469
Autor:
Zhan Zhao, Yubao Wang, Ran Zhou, Yi Li, Yun Gao, Dezhen Tu, Belinda Wilson, Sheng Song, Jing Feng, Jau-Shyong Hong, Jerrel L. Yakel
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Sepsis-associated acute brain inflammation, if unresolved, may cause chronic neuroinflammation and resultant neurodegenerative diseases. However, little is known how the transition from acute to chronic neuroinflammation, which is
Externí odkaz:
https://doaj.org/article/3c2c103d1b204c11948c033c254ee47c
The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-17 (2019)
Abstract Background Metabolic dysfunction and neuroinflammation are increasingly implicated in Parkinson’s disease (PD). The pentose phosphate pathway (PPP, a metabolic pathway parallel to glycolysis) converts glucose-6-phosphate into pentoses and
Externí odkaz:
https://doaj.org/article/b793c0b49bbc4d799f22f33a62c39788
Autor:
Liyan Hou, Xueying Zhou, Cong Zhang, Ke Wang, Xiaofang Liu, Yuning Che, Fuqiang Sun, Huihua Li, Qingshan Wang, Dan Zhang, Jau-Shyong Hong
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102119- (2021)
Externí odkaz:
https://doaj.org/article/8f8fc6cb2ca148328e768e204db6683e
Autor:
Ching-Long Lai, Chun-Chung Lu, Hui-Ching Lin, Yueh-Feng Sung, Yi-Pin Wu, Jau-Shyong Hong, Giia-Sheun Peng
Publikováno v:
Journal of the Formosan Medical Association, Vol 118, Iss 1, Pp 420-428 (2019)
Background/purpose: The main purpose of this study was to extend previously reported showing potent neuroprotective effect of valproic acid (VPA) in primary midbrain neuro-glial cultures to investigate whether VPA could protect dopamine (DA) neurons
Externí odkaz:
https://doaj.org/article/9bc45efef03f4a2d9b0f8ad2c201f7c4