Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Jau-Nian Chen"'
Autor:
Adam D. Langenbacher, Fei Lu, Lauren Crisman, Zi Yi Stephanie Huang, Douglas J. Chapski, Thomas M. Vondriska, Yibin Wang, Chen Gao, Jau-Nian Chen
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 5, p 221 (2023)
The PAF1 complex component Rtf1 is an RNA Polymerase II-interacting transcription regulatory protein that promotes transcription elongation and the co-transcriptional monoubiquitination of histone 2B. Rtf1 plays an essential role in the specification
Externí odkaz:
https://doaj.org/article/2247b419ebec41f88a84da7d1beec553
Autor:
Hirohito Shimizu, Simon Huber, Adam D. Langenbacher, Lauren Crisman, Jie Huang, Kevin Wang, Fabiola Wilting, Thomas Gudermann, Johann Schredelseker, Jau-Nian Chen
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Mitochondria critically regulate a range of cellular processes including bioenergetics, cellular metabolism, apoptosis, and cellular Ca2+ signaling. The voltage-dependent anion channel (VDAC) functions as a passageway for the exchange of ions, includ
Externí odkaz:
https://doaj.org/article/f1a4486601394aacbc108e43e8005254
Autor:
Adam D. Langenbacher, Hirohito Shimizu, Welkin Hsu, Yali Zhao, Alexandria Borges, Carla Koehler, Jau-Nian Chen
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Mitochondrial Ca2 + uptake influences energy production, cell survival, and Ca2 + signaling. The mitochondrial calcium uniporter, MCU, is the primary route for uptake of Ca2 + into the mitochondrial matrix. We have generated a zebrafish MCU mutant th
Externí odkaz:
https://doaj.org/article/909179c5e8a641d4bd9e38f2978d8e47
Autor:
Safiyyah Ziyad, Jesse D. Riordan, Ann M. Cavanaugh, Trent Su, Gloria E. Hernandez, Georg Hilfenhaus, Marco Morselli, Kristine Huynh, Kevin Wang, Jau-Nian Chen, Adam J. Dupuy, M. Luisa Iruela-Arispe
Publikováno v:
Cell Reports, Vol 22, Iss 5, Pp 1211-1224 (2018)
Summary: Given its role as the source of definitive hematopoietic cells, we sought to determine whether mutations initiated in the hemogenic endothelium would yield hematopoietic abnormalities or malignancies. Here, we find that endothelium-specific
Externí odkaz:
https://doaj.org/article/a74c22f7c9d148fc88f5c03dbb005087
Autor:
M. Luisa Iruela-Arispe, Robert Damoiseaux, Jau-Nian Chen, Matteo Pellegrini, Young Ah Goo, Byoung-Kyu Cho, Dana Song, Snezana Mirkov, Adam D. Langenbacher, Feiyang Ma, Vanessa M. Freitas, Gloria Hernandez, Divya P. Prajapati, Jonathan Freshman, Ana Mompeón, Georg Hilfenhaus
Metastases largely rely on hematogenous dissemination of tumor cells via the vascular system and significantly limit prognosis of patients with solid tumors. To colonize distant sites, circulating tumor cells must destabilize the endothelial barrier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44ae16b8fa594f02278f5673f0c895d3
https://doi.org/10.1158/0008-5472.c.6512095.v1
https://doi.org/10.1158/0008-5472.c.6512095.v1
Autor:
M. Luisa Iruela-Arispe, Robert Damoiseaux, Jau-Nian Chen, Matteo Pellegrini, Young Ah Goo, Byoung-Kyu Cho, Dana Song, Snezana Mirkov, Adam D. Langenbacher, Feiyang Ma, Vanessa M. Freitas, Gloria Hernandez, Divya P. Prajapati, Jonathan Freshman, Ana Mompeón, Georg Hilfenhaus
Effects of positive hits on endothelial barrier, cytoskeletal organization and tumor cell motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190d4476850e1d003b1ac19bf240c2a9
https://doi.org/10.1158/0008-5472.22425637.v1
https://doi.org/10.1158/0008-5472.22425637.v1
Autor:
M. Luisa Iruela-Arispe, Robert Damoiseaux, Jau-Nian Chen, Matteo Pellegrini, Young Ah Goo, Byoung-Kyu Cho, Dana Song, Snezana Mirkov, Adam D. Langenbacher, Feiyang Ma, Vanessa M. Freitas, Gloria Hernandez, Divya P. Prajapati, Jonathan Freshman, Ana Mompeón, Georg Hilfenhaus
Effect of drug hits on cortical actin and tumor cell migration and invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e8ac59834a9afc92b2a794da328fe4
https://doi.org/10.1158/0008-5472.22425634.v1
https://doi.org/10.1158/0008-5472.22425634.v1
Autor:
M. Luisa Iruela-Arispe, Robert Damoiseaux, Jau-Nian Chen, Matteo Pellegrini, Young Ah Goo, Byoung-Kyu Cho, Dana Song, Snezana Mirkov, Adam D. Langenbacher, Feiyang Ma, Vanessa M. Freitas, Gloria Hernandez, Divya P. Prajapati, Jonathan Freshman, Ana Mompeón, Georg Hilfenhaus
Phenotypes of the human pancreatic cell Ines and effects on endothelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1712d5098779c6fdf510e6e27a2ca2e1
https://doi.org/10.1158/0008-5472.22425643.v1
https://doi.org/10.1158/0008-5472.22425643.v1
Autor:
M. Luisa Iruela-Arispe, Robert Damoiseaux, Jau-Nian Chen, Matteo Pellegrini, Young Ah Goo, Byoung-Kyu Cho, Dana Song, Snezana Mirkov, Adam D. Langenbacher, Feiyang Ma, Vanessa M. Freitas, Gloria Hernandez, Divya P. Prajapati, Jonathan Freshman, Ana Mompeón, Georg Hilfenhaus
Methods and Reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d916a6a9bc63d785b37551be13a14bc
https://doi.org/10.1158/0008-5472.22425622.v1
https://doi.org/10.1158/0008-5472.22425622.v1
Autor:
M. Luisa Iruela-Arispe, Robert Damoiseaux, Jau-Nian Chen, Matteo Pellegrini, Young Ah Goo, Byoung-Kyu Cho, Dana Song, Snezana Mirkov, Adam D. Langenbacher, Feiyang Ma, Vanessa M. Freitas, Gloria Hernandez, Divya P. Prajapati, Jonathan Freshman, Ana Mompeón, Georg Hilfenhaus
Determination of niclosamide stability and approach for counting lung metastatic nodules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250ad6163dccec485c7d7c417350f0a0
https://doi.org/10.1158/0008-5472.22425625.v1
https://doi.org/10.1158/0008-5472.22425625.v1