Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jau Ling Huang"'
Autor:
Yung-Ding Bow, Ching-Chung Ko, Wen-Tsan Chang, Sih-Yan Chou, Chun-Tzu Hung, Jau-Ling Huang, Chih-Hua Tseng, Yeh-Long Chen, Ruei-Nian Li, Chien-Chih Chiu
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background The development of nonapoptotic programmed cell death inducers as anticancer agents has emerged as a cancer therapy field. Ferroptosis, ferrous ion-driven programmed cell death that is induced by redox imbalance and dysfunctional
Externí odkaz:
https://doaj.org/article/57f68ec0bec9413792b8d51e23484dff
Autor:
Chi-Han Huang, Yun-Cian Huang, Jun-Kai Xu, Si-Yun Chen, Lu-Chia Tseng, Jau-Ling Huang, Chang-Shen Lin
Publikováno v:
Cells, Vol 12, Iss 9, p 1288 (2023)
Immune checkpoint blockade (ICB) therapy can improve the survival of cancer patients with a high tumor mutation burden (TMB-H) or deficiency in DNA mismatch repair (dMMR) in their tumors. However, most cancer patients without TMB-H and dMMR do not be
Externí odkaz:
https://doaj.org/article/b7ecfd25726743249eed2dc06b72d7d2
Autor:
Chien-Chih Chiu, Yen-Chun Chen, Yung-Ding Bow, Jeff Yi-Fu Chen, Wangta Liu, Jau-Ling Huang, En-De Shu, Yen-Ni Teng, Chang-Yi Wu, Wen-Tsan Chang
Publikováno v:
Cancers; Volume 14; Issue 10; Pages: 2528
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is the leading cause of cancer-related mortality worldwide. Chemotherapy is the major treatment modality for advanced or unresectable HCC; unfortunately, chemoresistance results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc7a56f600fc1962bf1898cb6aa0525
Publikováno v:
Journal of personalized medicine. 12(4)
Cancer stem cells (CSCs) are a small subset of cancer cells and are thought to play a critical role in the initiation and maintenance of tumor mass. CSCs exhibit similar hallmarks to normal stem cells, such as self-renewal, differentiation, and homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1a96d929e209c503b210877a61f2cc
https://pubmed.ncbi.nlm.nih.gov/35455671
https://pubmed.ncbi.nlm.nih.gov/35455671
Publikováno v:
International journal of molecular sciences. 23(6)
Deficiency in DNA damage response (DDR) genes leads to impaired DNA repair functions that will induce genomic instability and facilitate cancer development. However, alterations of DDR genes can serve as biomarkers for the selection of suitable patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854033cef80da6dd580f8087b3ca92eb
https://pubmed.ncbi.nlm.nih.gov/35328658
https://pubmed.ncbi.nlm.nih.gov/35328658
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 2; Pages: 140
To improve the survival rate of cancer patients, biomarkers for both early diagnosis and patient stratification for appropriate therapeutics play crucial roles in precision oncology. Investigation of altered gene expression and the relevant molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4553de526d2457800316b1043dd003
https://pubmed.ncbi.nlm.nih.gov/35207629
https://pubmed.ncbi.nlm.nih.gov/35207629
Autor:
Yu-Chu Wang, Chung-Sheng Wang, Pei-Yi Chu, Long-Fong Chen, Yun-Chiao Cheng, Jau-Ling Huang, Hsing-Han Lu, Zih-Ting Zeng, Chang-Shen Lin, Yuan-Jen Lin, Ka-Wo Lee
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2053, p 2053 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2053, p 2053 (2020)
Arecoline is the principal alkaloid in the areca nut, a component of betel quids (BQs), which are carcinogenic to humans. Epidemiological studies indicate that BQ-chewing contributes to the occurrence of head and neck cancer (HNC). Previously, we hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346b2055e96eaae151c3d3f0867e1929
Autor:
Chang-Shen Lin, S.Y. Lu, Jau-Ling Huang, Yi-Hsiung Lin, Y.N. Lu, T.Y. Wong, H.H. Lu, C.C. Lin, C.C. Yang, P.S. Hung
Publikováno v:
Toxicology in Vitro. 33:80-87
The International Agency for Research on Cancer lists the principal component of betel quid (BQ), the areca nut, and that of cigarette smoke, benzo[a]pyrene (BaP), as Group 1 carcinogens. Epidemiological studies have shown that coexposure of BQ and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04bd614bb367a8fa954f14edc271b79
https://doi.org/10.1016/j.tiv.2016.02.007
https://doi.org/10.1016/j.tiv.2016.02.007
Autor:
Hsin Yi Jiang, Jeng-Jer Shieh, Szu Wei Mu, Yi Ju Chen, Shi Wei Huang, Chun Ying Wu, Sin Ting Wang, Shu Hao Chang, Jun Kai Kao, Jau Ling Huang
Publikováno v:
Journal of Dermatological Science. 81:182-191
Background The tumor suppressor p53 controls DNA repair, cell cycle, apoptosis, autophagy and numerous other cellular processes. Imiquimod (IMQ), a synthetic toll-like receptor (TLR) 7 ligand for the treatment of superficial basal cell carcinoma (BCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bc4a101e99c7ae98991f8d97e66415
https://doi.org/10.1016/j.jdermsci.2015.12.011
https://doi.org/10.1016/j.jdermsci.2015.12.011
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 79:39-47
DNA repair genes play critical roles in response to carcinogen-induced and anticancer therapy-induced DNA damage. Benzo[a]pyrene (BaP), the most carcinogenic polycyclic aromatic hydrocarbon (PAH), is classified as a group 1 carcinogen by Internationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cfad09d43bb8823e559f18081bcc70
https://doi.org/10.1080/15287394.2015.1104271
https://doi.org/10.1080/15287394.2015.1104271