Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jatinder K. Mukker"'
Autor:
Jatinder K. Mukker, George Dukes, Max Tolkoff, Lisi Wang, Cristina Almansa, Susanna Y. Huh, Mitsuhiro Nishihara, Diane Ramsden, Chunlin Chen
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 6, Pp 1532-1543 (2022)
Abstract Trazpiroben is a dopamine D2/D3 receptor antagonist under development for the treatment of gastroparesis. This phase I, open‐label, randomized, two‐way crossover study (NCT04121078) evaluated the effect of single‐dose intravenous rifam
Externí odkaz:
https://doaj.org/article/38b58aca274249bab33382058262b3db
Autor:
Lillian L. Siu, Timothy A. Yap, Sofia Genta, Gregory Pennock, Christine Hicking, Xiaoli You, Jatinder K. Mukker, Giuseppe Locatelli, Anthony W. Tolcher
Publikováno v:
Cancer Research. 83:CT171-CT171
M4076 is a potent and selective oral inhibitor of ataxia-telangiectasia mutated (ATM), a key kinase of the DNA damage response (DDR) involved in double-strand break repair. Preclinically, M4076 when combined with DNA damage-inducing therapy or other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8814332bed9b8663713f02aab75ff413
https://doi.org/10.1158/1538-7445.am2023-ct171
https://doi.org/10.1158/1538-7445.am2023-ct171
Autor:
Ruth Plummer, Anthony W. Tolcher, Timothy A. Yap, Giuseppe Sessa, Jatinder K. Mukker, Annick Seithel-Keuth, Christine Hicking, Zoltan Szucs, Ioannis Gounaris, Giuseppe Locatelli, Johann S. de Bono
Publikováno v:
Cancer Research. 83:CT272-CT272
Background: Ataxia telangiectasia and Rad3-related (ATR) protein kinase plays a critical role in the DNA damage response. M1774, a potent, selective, orally administered ATR inhibitor with antitumor activity in preclinical models, was evaluated in Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5f4efca87d08aee9056d8cfeb2ef327
https://doi.org/10.1158/1538-7445.am2023-ct272
https://doi.org/10.1158/1538-7445.am2023-ct272