Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jastrinjan Kaur"'
Autor:
Jastrinjan Kaur, Laura Soucek
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/351b0e14773c4c219e3c6d9daf3b0db1
Autor:
Marie-Eve Beaulieu, Sandra Martínez-Martín, Jastrinjan Kaur, Virginia Castillo Cano, Daniel Massó-Vallés, Laia Foradada Felip, Sergio López-Estévez, Erika Serrano del Pozo, Hugo Thabussot, Laura Soucek
Publikováno v:
Cancers, Vol 15, Iss 3, p 826 (2023)
MYC is an oncoprotein causally involved in the majority of human cancers and a most wanted target for cancer treatment. Omomyc is the best-characterized MYC dominant negative to date. In the last years, it has been developed into a therapeutic minipr
Externí odkaz:
https://doaj.org/article/c652344981924fa6814bc0f0ccdbb43a
Autor:
Mariano F. Zacarías-Fluck, Daniel Massó-Vallés, Fabio Giuntini, Íñigo González-Larreategui, Jastrinjan Kaur, Sílvia Casacuberta-Serra, Toni Jauset, Sandra Martínez-Martín, Génesis Martín-Fernández, Erika Serrano del Pozo, Laia Foradada, Judit Grueso, Lara Nonell, Marie-Eve Beaulieu, Jonathan R. Whitfield, Laura Soucek
Publikováno v:
Genes & Development. 37:303-320
MYC's key role in oncogenesis and tumor progression has long been established for most human cancers. In melanoma, its deregulated activity by amplification of 8q24 chromosome or by upstream signaling coming from activating mutations in the RAS/RAF/M
Autor:
Laura Soucek, Jonathan R. Whitfield, Lars-Gunnar Larsson, Violeta Serra, Joaquín Arribas, Marta Guzman, Marta Escorihuela, Antonio Luque-García, Loay Mahmoud, Mohammad Alzrigat, Miguel Ángel Morcillo, Sergio López-Estévez, Jastrinjan Kaur, Virginia Castillo Cano, Sílvia Casacuberta-Serra, Génesis Martín-Fernández, Erika Serrano, Sandra Martínez-Martín, Laia Foradada, Mariano F. Zacarías-Fluck, Fabio Giuntini, Toni Jauset, Marie-Eve Beaulieu, Daniel Massó-Vallés
MYC's role in promoting tumorigenesis is beyond doubt, but its function in the metastatic process is still controversial. Omomyc is a MYC dominant negative that has shown potent antitumor activity in multiple cancer cell lines and mouse models, regar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905558f9f525b058b676fca6f1e89484
https://doi.org/10.1158/2767-9764.c.6550557
https://doi.org/10.1158/2767-9764.c.6550557
Autor:
Marie-Eve Beaulieu, Elena Garralda, Sílvia Casacuberta-Serra, Sandra Sandra Martínez-Martín, Emiliano Calvo, Víctor Moreno, Sergio López-Estévez, Laia Foradada, Guzman Alonso, Elena Corral, Bernard Doger, Tatiana Hernández, Judit Grueso, Íñigo Íñigo González-Larreategui, Erika Serrano del Pozo, Hugo Thabussot, Virginia Castillo Cano, Mariano F. Mariano F. Zacarías-Fluck, Jastrinjan Kaur, Fabio Giuntini, Jonathan R. Whitfield, Josefa Morales, Manuela Niewel, Laura Soucek
Publikováno v:
Cancer Research. 83:3435-3435
Background: MYC is a key transcription factor driving and maintaining human tumors. Since MYC has long been perceived as an “undruggable” target, to date, there is still no MYC inhibitor approved for clinical use. However, we designed and validat
Autor:
Daniel Massó-Vallés, Marie-Eve Beaulieu, Toni Jauset, Fabio Giuntini, Mariano F. Zacarías-Fluck, Laia Foradada, Sandra Martínez-Martín, Erika Serrano, Génesis Martín-Fernández, Sílvia Casacuberta-Serra, Virginia Castillo Cano, Jastrinjan Kaur, Sergio López-Estévez, Miguel Ángel Morcillo, Mohammad Alzrigat, Loay Mahmoud, Antonio Luque-García, Marta Escorihuela, Marta Guzman, Joaquín Arribas, Violeta Serra, Lars-Gunnar Larsson, Jonathan R. Whitfield, Laura Soucek
MYC's role in promoting tumorigenesis is beyond doubt, but its function in the metastatic process is still controversial. Omomyc is a MYC dominant negative that has shown potent antitumor activity in multiple cancer cell lines and mouse models, regar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e128395dad6b974e90d6d40766210643
https://ddd.uab.cat/record/273055
https://ddd.uab.cat/record/273055
Publikováno v:
Cancer Research Communications
Autor:
Marie-Eve Beaulieu, Laura Soucek, Jonathan Whitfield, Mariano F. Zacarias-Fluck, Íñigo González-Larreategui, Génesis Martín-Fernández, Jastrinjan Kaur, Daniel Massó-Vallés, Sandra Martínez-Martín, Lamorna Brown-Swigart, David M. Virshup, Erika Serrano del Pozo, Toni Jauset, Sílvia Casacuberta-Serra, Babita Madan, Sergio López-Estévez, Gerard I. Evan
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Life Science Alliance
Life science alliance, vol 4, iss 5
Universitat Autònoma de Barcelona
Life Science Alliance
Life science alliance, vol 4, iss 5
Zacarías-Fluck, et al identify and validate the Wnt receptor Fzd9 as a key effector of Myc-Wnt signaling cross-talk in a mouse model of Myc-driven pancreatic insulinomas.
The huge cadre of genes regulated by Myc has obstructed the identificatio
The huge cadre of genes regulated by Myc has obstructed the identificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f47e88677effbd84eb77c2b01382aae
https://ddd.uab.cat/record/238774
https://ddd.uab.cat/record/238774