Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jastinder Sohal"'
Autor:
Hardev S. Pandha, Ruth Pettengell, Jastinder Sohal, Liesl Shears, Patricia Macanas Pirard, Richard Morgan
Supplementary Figure Legend from Antagonism of HOX/PBX Dimer Formation Blocks the In vivo Proliferation of Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01cc5c08c6426044412ad4ddc7a07ee
https://doi.org/10.1158/0008-5472.22367579.v1
https://doi.org/10.1158/0008-5472.22367579.v1
Autor:
Hardev S. Pandha, Ruth Pettengell, Jastinder Sohal, Liesl Shears, Patricia Macanas Pirard, Richard Morgan
Malignant melanoma is a cancer that arises from melanocyte cells in a complex but well-studied process, and which can only be successfully treated prior to metastasis as it is highly resistant to conventional therapies. A number of recent reports hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efa97563b6ba9456d4385fdc668bb3b
https://doi.org/10.1158/0008-5472.c.6495611
https://doi.org/10.1158/0008-5472.c.6495611
Autor:
Ruth Pettengell, Richard Morgan, Liesl Shears, Hardev Pandha, Jastinder Sohal, Patricia Macanas Pirard
Publikováno v:
Cancer Research. 67:5806-5813
Malignant melanoma is a cancer that arises from melanocyte cells in a complex but well-studied process, and which can only be successfully treated prior to metastasis as it is highly resistant to conventional therapies. A number of recent reports hav
Autor:
Francesco Galimi, Corinne B. Ocampo, Ronald M. Evans, Jastinder Sohal, Michelle M. Le Beau, Thomas Sternsdorf, Scott C. Kogan, Vernon T. Phan, Mei Lin Maunakea, Angela Silletto
Publikováno v:
Cancer Cell. 9:81-94
RARA becomes an acute promyelocytic leukemia (APL) oncogene by fusion with any of five translocation partners. Unlike RARalpha, the fusion proteins homodimerize, which may be central to oncogenic activation. This model was tested by replacing PML wit
Autor:
Nicholas C.P. Cross, Diya Lahiri, Jastinder Sohal, Donald Macdonald, John M. Goldman, Andrew Chase
Publikováno v:
British Journal of Haematology. 105:771-774
Aberrations of 13q are frequently found in myeloproliferative disorders (MPD). In a case of primary proliferative polycythaemia which transformed to myelofibrosis, karyotype analysis at transformation revealed an acquired t(4;13)(q25;q12). FISH and S
Autor:
Barbara A. Jennings, Andreas Reiter, Nicholas C.P. Cross, Shashikant Kulkarni, Andrew Chase, Donald Macdonald, Jesús M. Hernández, Cristina Gonçalves, Ricardo C.T. Aguiar, John M. Goldman, Jastinder Sohal
Publikováno v:
Blood. 92:1735-1742
The 8p11 myeloproliferative syndrome is a rare, aggressive condition associated with reciprocal translocations of chromosome band 8p11, most commonly the t(8;13)(p11;q12). To identify the genes involved in this translocation, we used fluorescence in
Autor:
Rüdiger Hehlmann, Nicholas C.P. Cross, Andreas Reiter, Andreas Hochhaus, Jastinder Sohal, Myrtle Y. Gordon, John M. Goldman, Stephen B. Marley, Pia Raanani
Publikováno v:
British Journal of Haematology. 102:1271-1278
To determine the source of residual disease detected in patients with chronic myeloid leukaemia (CML) in complete cytogenetic remission (n = 8) after treatment with interferon-α (IFN-α), we have tested CFU-GM colonies grown from bone marrow mononuc
Autor:
John M. Goldman, Andrew Chase, Jastinder Sohal, Donald Macdonald, Stephanie Coulthard, Melina Carapeti, Andreas Reiter, A. L. Lennard, Ricardo C.T. Aguiar, Nicholas C.P. Cross
Publikováno v:
Blood. 90:3130-3135
Two distinct leukemia syndromes are associated with abnormalities of chromosome band 8p11. First, a myeloproliferative disorder with features characteristic of both chronic myeloid leukemia and non-Hodgkin's lymphoma and second, an acute myeloid leuk
Autor:
Anthony H. Goldstone, Ricardo C. T. Aguiar, Ian M. Franklin, Frits van Rhee, John M. Goldman, Nicholas C.P. Cross, Jastinder Sohal, Melina Carapeti
Publikováno v:
British Journal of Haematology. 95:673-677
A number of fusion genes have been identified by study of acquired chromosomal translocations. Their detailed characterization has provided insights into mechanisms of leukaemogenesis and has enabled the development of molecular methods to assist in
Autor:
Elizabeth M. Davis, Bhumi Patel, Jastinder Sohal, Scott C. Kogan, Vernon T. Phan, Michelle M. Le Beau
Publikováno v:
Blood. 102:1072-1074
Acute promyelocytic leukemia (APL) is characterized by the PML-RARA fusion gene. To identify genetic changes that cooperate with PML-RARA, we performed spectral karyotyping analysis of myeloid leukemias from transgenic PML-RARA mice and from mice coe