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Autor:
Jastaniah, Ammar
Our lab has previously synthesized peptidomimetic cysteine protease inhibitors that are efficacious in mice models of Alzheimer's Disease.9 However, because they possess the highly reactive oxirane warhead, they exhibited high off-target effect as we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91df45145ffc2bd37e8fa7b541a8971d
Publikováno v:
ChemMedChem; 12/3/2020, Vol. 15 Issue 23, p2280-2285, 6p
Akademický článek
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Autor:
Knopp RC; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States., Jastaniah A; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States., Dubrovskyi O; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States., Gaisina I; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States.; UICentre (Drug Discovery @ UIC), University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States., Tai L; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago (UIC), Chicago, Illinois 60612, United States., Thatcher GRJ; Department of Pharmacology & Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona 85721, United States.
Publikováno v:
ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2021 Feb 02; Vol. 4 (1), pp. 372-385. Date of Electronic Publication: 2021 Feb 02 (Print Publication: 2021).