Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jasraj S. Bhachu"'
Autor:
Haresh Selvaskandan, Lee Er, Jonathan Barratt, Izabella Z.A. Pawluczyk, Matthew Nicholson, Jasraj S. Bhachu, Sean J. Barbour
Publikováno v:
Kidney International Reports
Introduction Immunoglobulin (Ig)A nephropathy (IgAN) is the most frequently diagnosed primary glomerulonephritis worldwide. Despite the common diagnostic feature of mesangial IgA-containing immune complex deposition, the clinical course of the diseas
Autor:
Izabella Z.A. Pawluczyk, Haresh Selvaskandan, Jonathan Barratt, Ian Roberts, William A Barratt, Jasraj S. Bhachu, Maria S F Soares, Jeremy R Brown, Yiqing Zeng, Rishi Sarania, Karen Molyneux
Publikováno v:
Nephrology Dialysis Transplantation. 35:1865-1877
BackgroundTubulointerstitial fibrosis is a powerful predictor of future progression inimmunoglobulin A (IgA) nephropathy (IgAN). Proximal tubular epithelial cells (PTECs), in concert with infiltrating macrophages, are regarded as the agents provocate
Autor:
Donald James Fraser, Jasraj S. Bhachu, Scott Taylor, Sean J. Barbour, Robert H. Jenkins, Karen Molyneux, Izabella Z.A. Pawluczyk, Jan U. Becker, Julio Saez-Rodriguez, Athanasios Didangelos, Edward G. Lyons, Jonathan Barratt, Javier Perales-Patón, Lee Er, Roberto Martin
Publikováno v:
Kidney international. 99(5)
Understanding why certain patients with IgA nephropathy progress to kidney failure while others maintain normal kidney function remains a major unanswered question. To help answer this, we performed miRNome profiling by next generation sequencing of
Autor:
Karen Molyneux, Jonathan Barratt, Jasraj S. Bhachu, John Feehally, Peter R. Mertens, David Wimbury, Masahiro Muto, Izabella Z.A. Pawluczyk
Publikováno v:
Kidney international. 92(6)
IgA nephropathy is characterized by mesangial deposition of IgA, mesangial cell proliferation, and extracellular matrix production. Mesangial cells bind IgA, but the identity of all potential receptors involved remains incomplete. The transferrin rec