Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jaspreet S Khurana"'
Autor:
Richard V Miller, Rafik Neme, Derek M Clay, Jananan S Pathmanathan, Michael W Lu, V Talya Yerlici, Jaspreet S Khurana, Laura F Landweber
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
AbstractThe germline-soma divide is a fundamental distinction in developmental biology, and different genes are expressed in germline and somatic cells throughout metazoan life cycles. Ciliates, a group of microbial eukaryotes, exhibit germline-somat
Externí odkaz:
https://doaj.org/article/76398594b0774a9dbc25b7dc22ef7507
Autor:
Estienne C Swart, John R Bracht, Vincent Magrini, Patrick Minx, Xiao Chen, Yi Zhou, Jaspreet S Khurana, Aaron D Goldman, Mariusz Nowacki, Klaas Schotanus, Seolkyoung Jung, Robert S Fulton, Amy Ly, Sean McGrath, Kevin Haub, Jessica L Wiggins, Donna Storton, John C Matese, Lance Parsons, Wei-Jen Chang, Michael S Bowen, Nicholas A Stover, Thomas A Jones, Sean R Eddy, Glenn A Herrick, Thomas G Doak, Richard K Wilson, Elaine R Mardis, Laura F Landweber
Publikováno v:
PLoS Biology, Vol 11, Iss 1, p e1001473 (2013)
The macronuclear genome of the ciliate Oxytricha trifallax displays an extreme and unique eukaryotic genome architecture with extensive genomic variation. During sexual genome development, the expressed, somatic macronuclear genome is whittled down t
Externí odkaz:
https://doaj.org/article/2c997db6921e48499101458b87b25641
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001246 (2010)
Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway
Externí odkaz:
https://doaj.org/article/5bbba711748a4dd0bb2bd7d5458251da
Autor:
Laura F. Landweber, John R. Bracht, Michael W Lu, Jaspreet S. Khurana, V Talya Yerlici, Hoge C, Rafik Neme, Richard Miller
Publikováno v:
Nucleic Acids Research
Extrachromosomal circular DNA (eccDNA) is both a driver of eukaryotic genome instability and a product of programmed genome rearrangements, but its extent had not been surveyed in Oxytricha, a ciliate with elaborate DNA elimination and translocation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5606d93e54633cbd75977562ee6e8dc3
https://doi.org/10.1093/nar/gkz725
https://doi.org/10.1093/nar/gkz725
Autor:
Jananan S. Pathmanathan, Jaspreet S. Khurana, Richard Miller, V. T. Yerlici, Laura F. Landweber, Michael W Lu, Derek M. Clay, Rafik Neme
The germline-soma divide is a fundamental distinction in developmental biology, and different genes are expressed in germline and somatic cells throughout metazoan life cycles. Ciliates, a group of microbial eukaryotes, exhibit germline-somatic nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01828c920f57d01de32415965b6860c3
https://doi.org/10.1101/2020.10.07.330092
https://doi.org/10.1101/2020.10.07.330092
Publikováno v:
RNA. 24:18-29
Dicer-dependent small noncoding RNAs play important roles in gene regulation in a wide variety of organisms. Endogenous small interfering RNAs (siRNAs) are part of an ancient pathway of transposon control in plants and animals. The ciliate, Oxytricha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88909d8ef4bc4f6fe3254acbc11c9aa0
https://doi.org/10.1261/rna.061333.117
https://doi.org/10.1261/rna.061333.117
Publikováno v:
RNA (New York, N.Y.). 24(1)
Dicer-dependent small noncoding RNAs play important roles in gene regulation in a wide variety of organisms. Endogenous small interfering RNAs (siRNAs) are part of an ancient pathway of transposon control in plants and animals. The ciliate, Oxytricha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa6afae3633f43f510f68388f285462d
https://pubmed.ncbi.nlm.nih.gov/29079634
https://pubmed.ncbi.nlm.nih.gov/29079634
Publikováno v:
The Journal of Cell Biology
Transposons are prominent features of most eukaryotic genomes and mobilization of these elements triggers genetic instability. Transposon silencing is particularly critical in the germline, which maintains the heritable genetic complement. Piwi-inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955c06c7a111b77e8e48480ae988dcf0
https://doi.org/10.1083/jcb.201006034
https://doi.org/10.1083/jcb.201006034
Autor:
Nadine Schultz, Birgit S. Koppetsch, Jaspreet S. Khurana, Hualin Xi, Fan Zhang, Hervé Seitz, Carla Andrea Klattenhoff, Anetta Nowosielska, Zhiping Weng, Phillip D. Zamore, Chengjian Li, William E. Theurkauf, Jia Xu, Soohyun Lee
Publikováno v:
Cell. 138(6):1137-1149
SummaryPiwi-interacting RNAs (piRNAs) silence transposons and maintain genome integrity during germline development. In Drosophila, transposon-rich heterochromatic clusters encode piRNAs either on both genomic strands (dual-strand clusters) or predom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1910627192f9f99a6a7b2f2864b1872
The RNA polymerase II (Pol-II) holoenzyme, responsible for messenger RNA production, typically consists of 10–12 subunits. Our laboratory previously demonstrated that maternally deposited, long, noncoding, template RNAs are essential for programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb3b13a90d2d242fe684f015035e439
https://europepmc.org/articles/PMC4096365/
https://europepmc.org/articles/PMC4096365/