Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Jasper W. van de Sande"'
1
Improved LC–MS identification of short homologous peptides using sequence-specific retention time predictors
Autor: Boudewijn Hollebrands, Jos A. Hageman, Jasper W. van de Sande, Bauke Albada, Hans-Gerd Janssen
Publikováno v: Analytical and Bioanalytical Chemistry, 415(14), 2715-2726
Analytical and Bioanalytical Chemistry 415 (2023) 14
Peptides are an important group of compounds contributing to the desired, as well as the undesired taste of a food product. Their taste impressions can include aspects of sweetness, bitterness, savoury, umami and many other impressions depending on t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f2232948b00eca338b49ecd061c884
https://doi.org/10.1007/s00216-023-04670-2
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3
PUFA-Derived N-Acylethanolamide Probes Identify Peroxiredoxins and Small GTPases as Molecular Targets in LPS-Stimulated RAW264.7 Macrophages
Autor: Ian-Arris de Bus, Antoine H. P. America, Norbert C. A. de Ruijter, Milena Lam, Jasper W. van de Sande, Mieke Poland, Renger F. Witkamp, Han Zuilhof, Michiel G. J. Balvers, Bauke Albada
Publikováno v: Acs Chemical Biology, 17(8), 2054-2064
Acs Chemical Biology 17 (2022) 8
We studied the mechanistic and biological origins of anti-inflammatory poly-unsaturated fatty acid-derived N-acylethanolamines using synthetic bifunctional chemical probes of docosahexaenoyl ethanolamide (DHEA) and arachidonoyl ethanolamide (AEA) in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c0781f01742234fa23d54a181005dd
https://research.wur.nl/en/publications/pufa-derived-n-acylethanolamide-probes-identify-peroxiredoxins-an
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4
Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines
Autor: Jeroen D. C. Codée, Adriaan J. Minnaard, Wendy A. Offen, Herman S. Overkleeft, Jasper W. van de Sande, Sybrin P. Schröder, Jianbing Jiang, Wouter W. Kallemeijn, Bogdan I. Florea, Chi-Lin Kuo, Gideon J. Davies, Johannes M. F. G. Aerts, Thomas J. M. Beenakker, Gijsbert A. van der Marel, Eva J. van Rooden, Marta Artola
Publikováno v: Chemical Communications, 53(93), 12528-12531. ROYAL SOC CHEMISTRY
Chemical Communications
Chemical Communications, 53(93), 12528-12531
Activity-based protein profiling has emerged as a powerful tool for visualizing glycosidases in complex biological samples. Several configurational cyclophellitol isomers have been shown to display high selectivity as probes for glycosidases processi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4345c69350b922b39e6447bc0d44838
https://doi.org/10.1039/c7cc07730k
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5
Discovery and Kinetic Profiling of 7‑Aryl-1,2,4-triazolo[4,3‑a]pyridines: Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2
Autor: Maarten L. J. Doornbos, Hilde Lavreysen, Alexandro Nunes, Adriaan P. IJzerman, Jordi Haubrich, Gary Tresadern, Sophie C. Vermond, Wilhelmus Drinkenburg, Laura H. Heitman, Jasper W. van de Sande, A. Ahnaou, Andrés A. Trabanco, Thea Mulder-Krieger, José María Cid
Publikováno v: Journal of medicinal chemistry, 60(15), 6704–6720
Journal of Medicinal Chemistry, 60(15), 6704-6720. AMER CHEMICAL SOC
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 60(15), 6704-6720
We report the synthesis and biological evaluation of a series of 7-aryl-1,2,4-triazolo[4,3-a]pyridines with mGlu2 positive allosteric modulator (PAM) activity and affinity. Besides traditional in vitro parameters of potency and affinity, kinetic para
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf3f2fdcd3f801936cef0c1df484262
http://hdl.handle.net/1887/55826
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