Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jasper Manning"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Actin is a multi-functional protein that is involved in numerous cellular processes including cytoskeleton regulation, cell migration, and cellular integrity. In these processes, actin’s role in respect to its structure, complex mechanical, and pro
Externí odkaz:
https://doaj.org/article/4d5b7826cd284c8a9f89b2e3f972152d
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Sertoli cells (SCs) are the only somatic cells that reside in seminiferous tubules of testis. They directly interact with and support the development of germ cells, thus have an indispensable role in the process of spermatogenesis. SCs first appear i
Externí odkaz:
https://doaj.org/article/90fca3b4a76f40adbac3562d274f88e4
Autor:
Matouš Vobořil, Jiří Březina, Tomáš Brabec, Jan Dobeš, Ondřej Ballek, Martina Dobešová, Jasper Manning, Richard S Blumberg, Dominik Filipp
Publikováno v:
eLife, Vol 11 (2022)
Medullary thymic epithelial cells (mTECs), which produce and present self-antigens, are essential for the establishment of central tolerance. Since mTEC numbers are limited, their function is complemented by thymic dendritic cells (DCs), which transf
Externí odkaz:
https://doaj.org/article/2ae0f9be8910423e819ebff66ddf8eea
Publikováno v:
Cells, Vol 11, Iss 19, p 3168 (2022)
Male infertility affects approximately 14% of all European men, of which ~44% are characterized as idiopathic. There is an urgency to identify the factors that affect male fertility. One such factor, Autoimmune Regulator (AIRE), a protein found in th
Externí odkaz:
https://doaj.org/article/644658f14fb24d26be2a6542c0c48c9c
Autor:
Ondrej Ballek, Jan Valečka, Martina Dobešová, Adéla Broučková, Jasper Manning, Pavel Řehulka, Jiří Stulík, Dominik Filipp
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
The initiation of T-cell signaling is critically dependent on the function of the member of Src family tyrosine kinases (SFKs), Lck. Upon TCR triggering, Lck kinase activity induces the nucleation of signal-transducing hubs that regulate the formatio
Externí odkaz:
https://doaj.org/article/f2fbc9c2880c4007849f268adc8526ba
Autor:
Tomas Brabec, Matouš Vobořil, Dagmar Schierova, Evgeny Valter, Iva Splichalova, Jan Dobeš, Jiri Brezina, Martina Dobesova, Aigerim Aidarova, Martin Jakubec, Jasper Manning, Richard Blumberg, Ari Waissman, Michal Kolar, Jan Kubovciak, Dagmar Srutkova, Tomas Hudcovic, Martin Schwarzer, Eva Fronkova, Tereza Pinkasova, Petr Jabandziev, Dominik Filipp
Publikováno v:
Mucosal Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5953e8a9c8ced62a8173fdb8a5dab1c
https://doi.org/10.1016/j.mucimm.2023.01.005
https://doi.org/10.1016/j.mucimm.2023.01.005
Autor:
Jiří Březina, Matouš Vobořil, Tomáš Brabec, Jan Dobeš, Ondřej Ballek, Martina Dobešová, Jasper Manning, Richard S Blumberg, Dominik Filipp
Publikováno v:
eLife, Vol 11 (2022)
eLife
eLife
Medullary thymic epithelial cells (mTECs), which produce and present self-antigens, are essential for the establishment of central tolerance. Since mTEC numbers are limited, their function is complemented by thymic dendritic cells (DCs), which transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0c699a2ccfa7f5bf33878f13eccc71
https://elifesciences.org/articles/71578
https://elifesciences.org/articles/71578
Publikováno v:
Immunology & Cell Biology. 93:384-395
The initiation of T-cell receptor (TCR) signaling, based on the cobinding of TCR and CD4-Lck heterodimer to a peptide-major histocompatibility complex II on antigen presenting cells, represents a classical model of T-cell signaling. What is less clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1de9fc940c8b0f180cb7c34bed5b4b1
https://doi.org/10.1038/icb.2014.100
https://doi.org/10.1038/icb.2014.100
Autor:
Martina Dobešová, Ondřej Ballek, Jasper Manning, Adéla Broučková, Dominik Filipp, Pavel Řehulka, Jiří Stulík, Jan Valečka
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 7 (2016)
Frontiers in Immunology, Vol 7 (2016)
The initiation of T-cell signaling is critically dependent on the function of the member of Src family tyrosine kinases, Lck. Upon T-cell antigen receptor (TCR) triggering, Lck kinase activity induces the nucleation of signal-transducing hubs that re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe8f5bef7cb60c1aae9baf536c0c5ec
http://europepmc.org/articles/PMC5081367
http://europepmc.org/articles/PMC5081367
Autor:
Li Jun Weng, Jasper Manning, Steven D. Gore, Anchalee Jiemjit, Michelle A. Rudek, Hetty E. Carraway, George J. Dover, Stephen B. Baylin, Elizabeth A. Sugar, Michael R. Grever, James G. Herman, James A. Zwiebel, Abbie Mays, Oliver Galm, Ming Zhao, Judith E. Karp, Carole B. Miller, Anthony J. Murgo, Michael A. Carducci, B. Douglas Smith, Tianna Dauses
Publikováno v:
Cancer Research. 66:6361-6369
Optimal reexpression of most genes silenced through promoter methylation requires the sequential application of DNA methyltransferase inhibitors followed by histone deacetylase inhibitors in tumor cell cultures. Patients with myelodysplastic syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1858945ffce4b1513a28020036a38eb5
https://doi.org/10.1158/0008-5472.can-06-0080
https://doi.org/10.1158/0008-5472.can-06-0080