Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jasper J. Van Gemst"'
Autor:
Marissa L. Maciej-Hulme, Jasper J. Van Gemst, Patience Sanderson, Angelique L. W. M. M. Rops, Jo H. Berden, Bart Smeets, I. Jonathan Amster, Ton J. Rabelink, Johan Van Der Vlag
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Proliferative forms of glomerulonephritis are characterized by the influx of leukocytes, albuminuria, and loss of kidney function. The glomerular endothelial glycocalyx is a thick carbohydrate layer that covers the endothelium and is comprised of hep
Externí odkaz:
https://doaj.org/article/5060c46b8253413ba7b4953347efe22b
Autor:
Jasper J van Gemst, Nathalie J H G Passmann, Angelique L W M M Rops, Toin H van Kuppevelt, Jo H Berden, Markus A Loeven, Ton J Rabelink, Bart Smeets, Johan van der Vlag
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261722 (2021)
Glomerulonephritis is an acquired serious glomerular disease, which involves the interplay of many factors such as cytokines, chemokines, inflammatory cells, and heparan sulfate (HS). We previously showed that blocking of inflammatory heparan sulfate
Externí odkaz:
https://doaj.org/article/cf2da31333814194a47f7bc43ed4528d
Autor:
Gosse J. Adema, Martijn H. den Brok, Torben Heise, Johan van der Vlag, Louis Boon, Victor R. Bloemendal, Jasper J. van Gemst, Melissa Wassink, Sarah M. Weischer, Natasja Balneger, Thomas J. Boltje, Christian Büll
Fig. S1 Effect of intratumoral injections with 20 mg/kg S1 Ac53FaxNeu5Ac on B16-F10WT tumor growth. Fig. S2 Responsiveness of melanoma and neuroblastoma cells to Ac53FaxNeu5Ac. S2 Fig. S3 10 mg/kg Ac53FaxNeu5Ac injections are well tolerated. S3 Fig.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b1f780de0d86d541bdfeccb10edc87
https://doi.org/10.1158/0008-5472.22419500
https://doi.org/10.1158/0008-5472.22419500
Autor:
Jasper J van Gemst, Markus A Loeven, Mark J J de Graaf, Jo H M Berden, Ton J Rabelink, Cornelis H Smit, Johan van der Vlag
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167336 (2016)
Glycosaminoglycans (GAGs) are linear negatively charged polysaccharides and important components of extracellular matrices and cell surface glycan layers such as the endothelial glycocalyx. The GAG family includes sulfated heparin, heparan sulfate (H
Externí odkaz:
https://doaj.org/article/b537aedec8a141b0b49c46f087c4a54a
Autor:
Markus A. Loeven, Anthony J. Day, Lambert P. van den Heuvel, Carolien M. S. Schophuizen, Viranga Tilakaratna, Johan van der Vlag, Jasper J. van Gemst, B. Jeroen Klevering
Publikováno v:
Investigative Ophthalmology and Visual Science, 59, 722-730
Investigative Ophthalmology and Visual Science, 59, 2, pp. 722-730
Loeven, M A, van Gemst, J J, Schophuizen, C M S, Tilakaratna, V, van Den Heuvel, L P, Day, A J, Klevering, B J & van Der Vlag, J 2018, ' A novel choroidal endothelial cell line has a decreased affinity for the age-related macular degeneration– associated complement factor h variant 402h ', Investigative Ophthalmology and Visual Science, vol. 59, no. 2, pp. 722-730 . https://doi.org/10.1167/iovs.IOVS-17-22893
Investigative Ophthalmology and Visual Science, 59, 2, pp. 722-730
Loeven, M A, van Gemst, J J, Schophuizen, C M S, Tilakaratna, V, van Den Heuvel, L P, Day, A J, Klevering, B J & van Der Vlag, J 2018, ' A novel choroidal endothelial cell line has a decreased affinity for the age-related macular degeneration– associated complement factor h variant 402h ', Investigative Ophthalmology and Visual Science, vol. 59, no. 2, pp. 722-730 . https://doi.org/10.1167/iovs.IOVS-17-22893
PURPOSE. Choroidal endothelial cells play a central role in the pathogenesis of age-related macular degeneration (AMD). Protocols for isolating primary choroidal endothelial cells have been described but require access to human donor eyes, which is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e6fac791457ef9244437821ff8d94d
http://hdl.handle.net/2066/187848
http://hdl.handle.net/2066/187848
Autor:
Melissa Wassink, Natasja Balneger, Sarah M Weischer, Gosse J. Adema, Jasper J. van Gemst, Torben Heise, Louis Boon, Martijn H. den Brok, Christian Büll, Thomas J. Boltje, Victor R. L. J. Bloemendal, Johan van der Vlag
Publikováno v:
Cancer Research
Cancer Research, 78, 13, pp. 3574-3588
Cancer Research, 78(13), 3574-3588. American Association for Cancer Research Inc.
Cancer Research, 78, 3574-3588
Cancer Research, 78, 13, pp. 3574-3588
Cancer Research, 78(13), 3574-3588. American Association for Cancer Research Inc.
Cancer Research, 78, 3574-3588
Contains fulltext : 193642.pdf (Author’s version postprint ) (Open Access) Contains fulltext : 193642p.pdf (Publisher’s version ) (Closed access) Sialic acid sugars on the surface of cancer cells have emerged as potent immune modulators that cont
Autor:
Toin H. van Kuppevelt, Markus A. Loeven, Jo H. M. Berden, Johan van der Vlag, Iris Eversen, Jeffrey D. Esko, Xander M R van Wijk, Angelique L.W.M.M. Rops, Ton J. Rabelink, Henry B.P.M. Dijkman, Jasper J. van Gemst
Publikováno v:
Kidney International, 86(5), 932-942
Kidney International. Supplement, 86, 5, pp. 932-42
Kidney international, vol 86, iss 5
Kidney International. Supplement, 86, 932-42
Kidney International. Supplement, 86, 5, pp. 932-42
Kidney international, vol 86, iss 5
Kidney International. Supplement, 86, 932-42
Item does not contain fulltext The glomerular endothelial glycocalyx is postulated to be an important modulator of permeability and inflammation. The glycocalyx consists of complex polysaccharides, the main functional constituent of which, heparan su
Autor:
Markus A. Loeven, Mark de Graaf, Jasper J. van Gemst, Johan van der Vlag, Jo H. M. Berden, Ton J. Rabelink, Cornelis H. Smit
Publikováno v:
PLoS ONE
PLoS ONE, 11(11)
PLoS One, 11, 11
PLoS One, 11
PLoS ONE, Vol 11, Iss 11, p e0167336 (2016)
PLoS ONE, 11(11)
PLoS One, 11, 11
PLoS One, 11
PLoS ONE, Vol 11, Iss 11, p e0167336 (2016)
Contains fulltext : 171325.pdf (Publisher’s version ) (Open Access) Glycosaminoglycans (GAGs) are linear negatively charged polysaccharides and important components of extracellular matrices and cell surface glycan layers such as the endothelial gl
Autor:
Jasper J. van Gemst, Werner J.H. Koopman, Herman G.P. Swarts, Cindy E.J. Dieteren, Piotr Maczuga, Peter H.G.M. Willems, Rosalinde Masereeuw, Janny G. P. Peters, Jan A.M. Smeitink, Leo G.J. Nijtmans
Publikováno v:
Journal of Biological Chemistry, 287, 41851-60
Journal of Biological Chemistry, 287, 50, pp. 41851-60
Journal of Biological Chemistry, 287, 50, pp. 41851-60
Contains fulltext : 109628.pdf (Publisher’s version ) (Open Access) Studies employing native PAGE suggest that most nDNA-encoded CI subunits form subassemblies before assembling into holo-CI. In addition, in vitro evidence suggests that some subuni