Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jasper Götting"'
Autor:
Alice Rovai, BoMee Chung, Qingluan Hu, Sebastian Hook, Qinggong Yuan, Tibor Kempf, Florian Schmidt, Dirk Grimm, Steven R. Talbot, Lars Steinbrück, Jasper Götting, Jens Bohne, Simon A. Krooss, Michael Ott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Hemochromatosis is a metabolic disorder caused by mutations in the HFE gene. Here, the authors show that a single administration of AAV8 vectors expressing an Adenine Base Editor facilitates efficient in vivo gene correction in hepatocytes and leads
Externí odkaz:
https://doaj.org/article/41baa3360d14427b871c13b614264a6d
Autor:
Adrian Fritz, Andreas Bremges, Zhi-Luo Deng, Till Robin Lesker, Jasper Götting, Tina Ganzenmueller, Alexander Sczyrba, Alexander Dilthey, Frank Klawonn, Alice Carolyn McHardy
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-19 (2021)
Externí odkaz:
https://doaj.org/article/4514c35b142f47ef960e062abba914bb
Autor:
Melanie Bühler, Sandra Runft, Dandan Li, Jasper Götting, Claudia N. Detje, Vanessa Nippold, Melanie Stoff, Andreas Beineke, Thomas Schulz, Ulrich Kalinke, Wolfgang Baumgärtner, Ingo Gerhauser
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type I Interferons (IFN-I) are important inducers of the antiviral immune response and immune modulators. IFN-β is the most highly expressed IFN-I in the central nervous system (CNS). The infection of SJL mice with the BeAn or the DA strain of Theil
Externí odkaz:
https://doaj.org/article/b7fc626292294a8e9fbef9130c864822
Autor:
Jasper Götting, Katrin Lazar, Nicolás M. Suárez, Lars Steinbrück, Tabea Rabe, Rangmar Goelz, Thomas F. Schulz, Andrew J. Davison, Klaus Hamprecht, Tina Ganzenmueller
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Reactivation and shedding of human cytomegalovirus (HCMV) in breast milk during lactation is highly frequent in HCMV-seropositive mothers. This represents a key transmission route for postnatal HCMV infection and can lead to severe disease in preterm
Externí odkaz:
https://doaj.org/article/e9a135d933e847c884106a95ce93ff4e
Autor:
Abdul Rahman Siregar, Sabine Gärtner, Jasper Götting, Philipp Stegen, Artur Kaul, Thomas F. Schulz, Stefan Pöhlmann, Michael Winkler
Publikováno v:
Viruses, Vol 14, Iss 1, p 91 (2022)
Primate simplex viruses, including Herpes simplex viruses 1 and 2, form a group of closely related herpesviruses, which establish latent infections in neurons of their respective host species. While neuropathogenic infections in their natural hosts a
Externí odkaz:
https://doaj.org/article/ad247bb36fd542399be7153f7e15d6d7
Autor:
Ekaterina Chukhno, Sabine Gärtner, Abdul Rahman Siregar, Alexander Mehr, Marie Wende, Stoyan Petkov, Jasper Götting, Akshay Dhingra, Thomas Schulz, Stefan Pöhlmann, Michael Winkler
Publikováno v:
Viruses, Vol 11, Iss 11, p 1026 (2019)
The transmission of Macacine alphaherpesvirus 1 (McHV-1) from macaques, the natural host, to humans causes encephalitis. In contrast, human infection with Cercopithecine alphaherpesvirus 2 (CeHV-2), a closely related alphaherpesvirus from African ver
Externí odkaz:
https://doaj.org/article/ae4b722aec9b43e1a7303f02c80f85e3
Autor:
Faranaz Atschekzei, Natalia Dubrowinskaja, Georgios Sogkas, Torsten Witte, Reinhold E. Schmidt, Bodo Grimbacher, Ulrich Baumann, Katharina Schütz, Jasper Götting, Nicolaus Schwerk, Lars Steinbrück
Publikováno v:
Int Arch Allergy Immunol
Introduction: Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders characterized by increased susceptibility to infections, immune dysregulation, and/or malignancy. Genetic studies, especially during the last decade, led to a bett
Autor:
Nicolás M. Suárez, Tina Ganzenmueller, Jasper Götting, Andrew J. Davison, Akshay Dhingra, Thomas F. Schulz, Jasmin Zischke, Penelope C. Kay-Fedorov, Eva M. Weissinger, P R Varanasi, Albert Heim, Lars Steinbrueck, Salvatore Camiolo
Publikováno v:
Medical Microbiology and Immunology
Human cytomegalovirus (HCMV) is an important opportunistic pathogen in allogeneic haematopoietic stem cell transplant (HSCT) recipients. High-throughput sequencing of target-enriched libraries was performed to characterise the diversity of HCMV strai
Publikováno v:
Virus evolution. 8(2)
Type 41 of human adenovirus species F (HAdV-F41) is a frequent aetiology of gastroenteritis in children, and nosocomial as well as kindergarten outbreaks have been frequently described. In contrast to other HAdV types, HAdV-F41 was not associated wit
Autor:
Melanie Bühler, Sandra Runft, Dandan Li, Jasper Götting, Claudia N. Detje, Vanessa Nippold, Melanie Stoff, Andreas Beineke, Thomas Schulz, Ulrich Kalinke, Wolfgang Baumgärtner, Ingo Gerhauser
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type I Interferons (IFN-I) are important inducers of the antiviral immune response and immune modulators. IFN-β is the most highly expressed IFN-I in the central nervous system (CNS). The infection of SJL mice with the BeAn or the DA strain of Theil