Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jasper A. Soppe"'
Autor:
Gloria Griffante, Francesca Gugliesi, Selina Pasquero, Valentina Dell’Oste, Matteo Biolatti, Ari J. Salinger, Santanu Mondal, Paul R. Thompson, Eranthie Weerapana, Robert J. Lebbink, Jasper A. Soppe, Thomas Stamminger, Virginie Girault, Andreas Pichlmair, Gábor Oroszlán, Donald M. Coen, Marco De Andrea, Santo Landolfo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Citrullination is a posttranslational modification of arginines. Here, the authors show that HCMV infection increases citrullination of host and virus proteins to promote infection and that citrullinated interferon-inducible protein IFIT1 is impaired
Externí odkaz:
https://doaj.org/article/d9f89f1cfaed42dc92c156e171d58d7e
Autor:
Santo Landolfo, Jasper A. Soppe, Donald M. Coen, Marco De Andrea, Virginie Girault, Gloria Griffante, Gábor Oroszlán, Thomas Stamminger, Robert Jan Lebbink, Andreas Pichlmair, Santanu Mondal, Ari J. Salinger, Selina Pasquero, Eranthie Weerapana, Matteo Biolatti, Valentina Dell'Oste, Paul R. Thompson, Francesca Gugliesi
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Citrullination is the conversion of arginine-to-citrulline by protein arginine deiminases (PADs), whose dysregulation is implicated in the pathogenesis of various types of cancers and autoimmune diseases. Consistent with the ability of human cytomega
Autor:
Emmanuel J. H. J. Wiertz, Hendrik de Buhr, Robert Jan Lebbink, Elisabeth Kruse, Marjolein J. G. Hooykaas, Jasper A. Soppe
Publikováno v:
RNA Biology
MicroRNAs (miRNAs) are small RNA molecules that post-transcriptionally regulate gene expression through silencing of complementary target mRNAs. miRNAs are involved in many biological processes, including cell proliferation, differentiation, cell sig
Autor:
Michiel van Gent, Ingrid G. J. Boer, Dik van Leenen, Jasper A. Soppe, Marjolein J. G. Hooykaas, Emmanuel J. H. J. Wiertz, Elisabeth Kruse, Marian J. A. Groot Koerkamp, Maaike E. Ressing, Robert Jan Lebbink, Frank C. P. Holstege
Publikováno v:
Journal of Immunology, 198(10), 4062-4073
Journal of Immunology, 198(10), 4062. American Association of Immunologists
Journal of Immunology, 198(10), 4062. American Association of Immunologists
Type I IFNs play critical roles in orchestrating the antiviral defense by inducing direct antiviral activities and shaping the adaptive immune response. Viruses have evolved numerous strategies to specifically interfere with IFN production or its dow
Autor:
Robert Jan Lebbink, Jasper A. Soppe
Publikováno v:
Trends in Microbiology, 25(10), 833. Elsevier Limited
The clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems are RNA-guided sequence-specific prokaryotic antiviral immune systems. In prokaryotes, small RNA molecules guide Cas effector endonucleases to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc3ac9d6705db8093d96995064ce8b5
https://dspace.library.uu.nl/handle/1874/360707
https://dspace.library.uu.nl/handle/1874/360707
Autor:
Annemarie Kuipers, Evelien T.M. Berends, Jos A. G. van Strijp, Johanna F. Dekkers, Suzan H.M. Rooijakkers, Reindert Nijland, Jasper A. Soppe
Publikováno v:
Cellular Microbiology. 15:1955-1968
The plasma proteins of the complement system fulfil important immune defence functions, including opsonization of bacteria for phagocytosis, generation of chemo-attractants and direct bacterial killing via the Membrane Attack Complex (MAC or C5b-9).
Autor:
Jasper A. Soppe, Hatice Orhan, Carla J. C. de Haas, Piet C. Aerts, Maartje Ruyken, Piet Gros, Evelien T.M. Berends, Ronald D. Gorham, Suzan H.M. Rooijakkers
Publikováno v:
BMC Biology
BMC Biology, 13(1). BioMed Central Ltd.
BMC Biology, 13(1). BioMed Central Ltd.
Background Complement is a large protein network in plasma that is crucial for human immune defenses and a major cause of aberrant inflammatory reactions. The C5 convertase is a multi-molecular protease complex that catalyses the cleavage of native C
Autor:
Evelien T M, Berends, Johanna F, Dekkers, Reindert, Nijland, Annemarie, Kuipers, Jasper A, Soppe, Jos A G, van Strijp, Suzan H M, Rooijakkers
Publikováno v:
Cellular microbiology. 15(12)
The plasma proteins of the complement system fulfil important immune defence functions, including opsonization of bacteria for phagocytosis, generation of chemo-attractants and direct bacterial killing via the Membrane Attack Complex (MAC or C5b-9).