RNA Sequencing Elucidates Drug-Specific Mechanisms of Antibiotic Tolerance and Resistance in Mycobacterium abscessus

Autor: Wouter Hoefsloot, Huub J. M. Op den Camp, Jasper J N Sangen, Kornelia Neveling, Jordy P. M. Coolen, Michael Kwint, R. Andres Floto, Sophie Burbaud, Jodie A. Schildkraut, Heiman F. L. Wertheim, Jakko van Ingen, Lindsey H.M. te Brake

Publikováno v: Antimicrobial Agents and Chemotherapy, 66, 1, pp. 1-24
Antimicrobial Agents and Chemotherapy, 66
Antimicrobial Agents and Chemotherapy, 66, 1-24
Antimicrobial Agents and Chemotherapy, 66, 1
Antimicrobial Agents and Chemotherapy

Contains fulltext : 248649.pdf (Publisher’s version ) (Open Access) Mycobacterium abscessus is an opportunistic pathogen notorious for its resistance to most classes of antibiotics and low cure rates. M. abscessus carries an array of mostly unexplo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6764bf643354247a6aa7c66b4c9f04
https://doi.org/10.1128/aac.01509-21

Magnitude and Sources of Sediment Input to the Mackenzie Delta, Northwest Territories, 1974–94

Autor: Carson, M. A., Jasper, J. N., Conly, F. M.

Publikováno v: Arctic, 1998 Jun 01. 51(2), 116-124.

Externí odkaz: https://www.jstor.org/stable/40488391

A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria

Autor: Lian J. Pennings, Wouter Hoefsloot, Sanne M.H. Zweijpfenning, Elin M. Svensson, Cecile Magis-Escurra, Mike Marvin Ruth, Jasper J. N. Sangen, Saskia Kuipers, Heiman F. L. Wertheim, Rob E. Aarnoutse, Jakko van Ingen, Karlijn Remmers

Publikováno v: Journal of Antimicrobial Chemotherapy, 74, 935-943
Journal of Antimicrobial Chemotherapy, 74, 4, pp. 935-943

Item does not contain fulltext BACKGROUND: Non-tuberculous mycobacteria (NTM) infections are hard to treat. New antimicrobial drugs and smarter combination regimens are needed. OBJECTIVES: Our aim was to determine the in vitro activity of bedaquiline

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690ee478e35690917066b549ae9ff397
https://pubmed.ncbi.nlm.nih.gov/30649327

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Nifurtimox Is Ineffective against Drug-Resistant Mycobacteria

Autor: Heiman F. L. Wertheim, Jasper J. N. Sangen, Jakko van Ingen, Mike Marvin Ruth

Publikováno v: Antimicrobial Agents and Chemotherapy, 61, e01233-17-e01233-17
Antimicrobial Agents and Chemotherapy, 61, 9, pp. e01233-17-e01233-17

Item does not contain fulltext

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be71bb53929195c154a22dda8a7cb4d
https://doi.org/10.1128/AAC.01233-17