Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jason X. Tang"'
Publikováno v:
Expert Opinion on Drug Discovery. 16:1467-1482
Introduction: To discover and develop a peptide, protein, or antibody into a drug requires overcoming multiple challenges to obtain desired properties. Proteolytic stability is one of the challenge...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c635f90f1492fc3bd27b46befaff4f
https://doi.org/10.1080/17460441.2021.1942837
https://doi.org/10.1080/17460441.2021.1942837
Publikováno v:
The FEBS journalReferences. 289(9)
Insulin receptor (IR) phosphorylation is critical for the assessment of the extent of IR agonism and nuances in the downstream signaling cascade. A thorough identification and monitoring of the phosphorylation events is important for understanding th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06450f797f5846ce1920600d2a937197
https://pubmed.ncbi.nlm.nih.gov/34826178
https://pubmed.ncbi.nlm.nih.gov/34826178
Autor:
Qian Liu, Ruth E. Gimeno, Jason X. Tang, Gavin C. Barnard, Xilin Liu, Yong Du, Jorge Alsina-Fernandez, Paul J. Emmerson, Avinash Muppidi, Bei B Zhang, Richard Todd Pickard, Matthew J Hamang, Bei Shan, Tamer Coskun, Pamela Jean Mitchell, Malgorzata Donata Gonciarz, Kimberly K Ballman, John H. Sloan, Xinle Wu, Xudong Mao, Lisa A Foltz, Feng Wang, Dana Sindelar, Robert W. Siegel
Publikováno v:
Nature Medicine. 23:1215-1219
Growth/differentiation factor 15 (GDF15), also known as MIC-1, is a distant member of the transforming growth factor-β (TGF-β) superfamily and has been implicated in various biological functions, including cancer cachexia, renal and heart failure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2502200f39c5bdc1b589339efb20908a
https://doi.org/10.1038/nm.4393
https://doi.org/10.1038/nm.4393
Autor:
Jim D. Durbin, Patel Chetankumar Natvarlal, Kai Zhang, Scott P. Bauer, Jason X. Tang, Tatiyana L. Shiyanova, Julian Davies
Publikováno v:
Journal of Pharmaceutical Sciences. 105:512-518
Aspartate (Asp) isomerization is a common degradation pathway and a potential critical quality attribute that needs to be well characterized during the optimization and development of therapeutic antibodies. A putative Asp-serine (Ser) isomerization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fb6f22bc1321f4312818354ee3e76f
https://doi.org/10.1016/s0022-3549(15)00185-9
https://doi.org/10.1016/s0022-3549(15)00185-9