Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jason Wolk"'
Publikováno v:
eLife, Vol 10 (2021)
Associative learning allows animals to use past experience to predict future events. The circuits underlying memory formation support immediate and sustained changes in function, often in response to a single example. Larval Drosophila is a genetic m
Externí odkaz:
https://doaj.org/article/c297a426ab20457b8b752349f5756e47
Publikováno v:
eLife, Vol 7 (2018)
Sensory systems relay information about the world to the brain, which enacts behaviors through motor outputs. To maximize information transmission, sensory systems discard redundant information through adaptation to the mean and variance of the envir
Externí odkaz:
https://doaj.org/article/c21e4ae7f89241f68b3617ce823dedaf
Autor:
Kim D Allen, Matthew J Regier, Changchi Hsieh, Panayiotis Tsokas, Maya Barnard, Shwetha Phatarpekar, Jason Wolk, Todd C Sacktor, André A Fenton, A Iván Hernández
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0203374 (2018)
The transition from short-term to long-term forms of synaptic plasticity requires protein synthesis and new gene expression. Most efforts to understand experience-induced changes in neuronal gene expression have focused on the transcription products
Externí odkaz:
https://doaj.org/article/3107d3cc03814cc89e1c93bd4807af16
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Synaptic dysfunction is thought to play a major role in memory impairment in Alzheimer’s disease (AD). PARP-1 has been identified as an epigenetic regulator of plasticity and memory. Thus, we hypothesize that PARP-1 may be altered in postmortem hip
Externí odkaz:
https://doaj.org/article/993b7ccb79c04fb58430078b2b3a1410
Autor:
Kim D Allen, Andrei V Gourov, Christopher Harte, Peng Gao, Clarice Lee, Darlene Sylvain, Joshua M Splett, William C Oxberry, Paula S van de Nes, Matthew J Troy-Regier, Jason Wolk, Juan M Alarcon, A Iván Hernández
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104364 (2014)
Long-term memory (LTM) formation requires new protein synthesis and new gene expression. Based on our work in Aplysia, we hypothesized that the rRNA genes, stimulation-dependent targets of the enzyme Poly(ADP-ribose) polymerase-1 (PARP-1), are primar
Externí odkaz:
https://doaj.org/article/25063816b40f43d28fe0314baf7f13c0
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Associative learning allows animals to use past experience to predict future events. The circuits underlying memory formation support immediate and sustained changes in function, often in response to a single example. Larval Drosophila is a genetic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247eff172c6e049af1e9e17cccb57b74
https://doi.org/10.1101/2021.04.15.440041
https://doi.org/10.1101/2021.04.15.440041
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Neural Plasticity
Neural Plasticity
Synaptic dysfunction is thought to play a major role in memory impairment in Alzheimer’s disease (AD). PARP-1 has been identified as an epigenetic regulator of plasticity and memory. Thus, we hypothesize that PARP-1 may be altered in postmortem hip
Autor:
André A. Fenton, Matthew J. Regier, Panayiotis Tsokas, Shwetha Phatarpekar, A. Iván Hernández, Maya Barnard, Changchi Hsieh, Todd Charlton Sacktor, Jason Wolk, Kim D. Allen
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0203374 (2018)
PLoS ONE
PLoS ONE
The transition from short-term to long-term forms of synaptic plasticity requires protein synthesis and new gene expression. Most efforts to understand experience-induced changes in neuronal gene expression have focused on the transcription products