Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jason Walther"'
Autor:
Shashi Malladi, Michael J. Coolbaugh, Crystal Thomas, Sushmitha Krishnan, Chad T. Varner, Jason Walther, Kevin P. Brower
Publikováno v:
Journal of Membrane Science. 677:121633
Publikováno v:
Biotechnology and Bioengineering. 116:320-332
In this study, we investigated the effects of alternating tangential flow (ATF) cell separation on high-density perfusion cultures. We have developed methods to estimate theoretical residence times of cells in the ATF system and discovered that long
Autor:
Lisa Connell-Crowley, Kelley C. Rogers, Allison Haug, Eric Fallon, David Pollard, Mark Brower, Maen Qadan, Jason Walther, Ciaran Brady, Timothy S. Charlebois, Michael Coolbaugh, Christopher Gillespie, Kelvin H. Lee, Ruben G. Carbonell, Gene Schaefer, Jeffrey Baker, Roger Hart, Michael A. Phillips, John Erickson, Jon Coffman, Irina Ramos, Eric Garr, Shawn Barrett, Gregg Nyberg
Publikováno v:
Biotechnology and Bioengineering
An ambitious 10‐year collaborative program is described to invent, design, demonstrate, and support commercialization of integrated biopharmaceutical manufacturing technology intended to transform the industry. Our goal is to enable improved contro
Autor:
Marcus Fiadeiro, Brad Bouchard, Nihal Tugcu, Rohan Patil, Tarl Vetter, Jason Walther, Kevin Brower, Emily Davenport, Chad Varner, Michael Coolbaugh
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 118(9)
There has been increasing momentum recently in the biopharmaceutical industry to transition from traditional batch processes to next-generation integrated and continuous biomanufacturing. This transition from batch to continuous is expected to offer
Autor:
Jason Walther
Publikováno v:
Journal of Fluency Disorders. 58:120-122
Autor:
Chris Hwang, Jason Walther, Jiuyi Lu, Jean McLarty, Myles Hollenbach, Kevin Brower, Marcella Yu
Publikováno v:
Biotechnology journal. 14(2)
In this study, the authors compared the impacts of fed-batch and perfusion platforms on process and product attributes for IgG1- and IgG4-producing cell lines. A "plug-and-play" approach is applied to both platforms at bench scale, using commercially
Autor:
Rohan, Patil, Jason, Walther
Publikováno v:
Advances in biochemical engineering/biotechnology. 165
Continuous biomanufacturing of recombinant therapeutic proteins offers several potential advantages over conventional batch processing, including reduced cost of goods, more flexible and responsive manufacturing facilities, and improved and consisten
Autor:
Jason Walther, Rohan Patil
Publikováno v:
New Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins ISBN: 9783319971087
Continuous biomanufacturing of recombinant therapeutic proteins offers several potential advantages over conventional batch processing, including reduced cost of goods, more flexible and responsive manufacturing facilities, and improved and consisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6be855b7c9708f0ed8066c9c2ce1498a
https://doi.org/10.1007/10_2016_58
https://doi.org/10.1007/10_2016_58
Publikováno v:
Biotechnology Journal. 13:1700518
13 C metabolic flux analysis (MFA) provides a rigorous approach to quantify intracellular metabolism of industrial cell lines. In this study, 13 C MFA was used to characterize the metabolic response of Chinese hamster ovary (CHO) cells to a novel med
Autor:
Timothy W. Meyer, Jared D. Miller, Diana C. Dinh, Natalie S. Recht, Thomas H. Hostetter, John W.T. Peattie, Jason Walther
Publikováno v:
Journal of the American Society of Nephrology. 18:868-874
The capacity of sorbent systems to increase solute clearances above the levels that are provided by hemodialysis has not been well defined. This study assessed the extent to which solute clearances can be increased by addition of a sorbent to the dia