Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jason W. Middleton"'
Publikováno v:
Physiological Reports, Vol 7, Iss 19, Pp n/a-n/a (2019)
Abstract The central nucleus of the amygdala (CeA) is a primarily GABAergic brain region implicated in stress and addictive disorders. Using in vitro slice electrophysiology, many studies measure GABAergic neurotransmission to evaluate the impact of
Externí odkaz:
https://doaj.org/article/9c5317a9345d4c8e976b47d3507746fb
Autor:
Marcus M. Weera, Allyson L. Schreiber, Elizabeth M. Avegno, Jason W. Middleton, Nicholas W. Gilpin
Publikováno v:
Alcohol. 109:71
Autor:
Elizabeth A Fucich, Scott Edwards, Nicholas W. Gilpin, Patricia E. Molina, Jason W. Middleton, Zachary F. Stielper, Cecilia J. Hillard
Publikováno v:
J Neurotrauma
Traumatic brain injury (TBI) affects approximately 3 million Americans yearly and increases vulnerability to developing psychiatric comorbidities. Alcohol use disorder (AUD) is the most prevalent psychiatric diagnosis preceding injury and TBI may inc
Autor:
Alejandra Jacotte-Simancas, Jason W. Middleton, Zachary F. Stielper, Scott Edwards, Patricia E. Molina, Nicholas W. Gilpin
Publikováno v:
J Neurotrauma
Traumatic brain injury (TBI) is defined as brain damage produced by an external mechanical force that leads to behavioral, cognitive, and psychiatric sequelae. The basolateral amygdala (BLA) is involved in emotional regulation, and its function and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1953735eac0ba27d09676b446fe463e8
https://europepmc.org/articles/PMC8978566/
https://europepmc.org/articles/PMC8978566/
Publikováno v:
Psychopharmacology (Berl)
Opioid drugs are a first-line treatment for severe acute pain and other chronic pain conditions, but long-term opioid drug use produces opioid-induced hyperalgesia (OIH). Co-administration of cannabinoids with opioid receptor agonists produce anti-no
In an effort to reduce reliance on opioids for the treatment of pain in the clinic, ongoing work is testing the utility of cannabinoid drugs as a potential alternative for treatment of chronic pain. We tested chronic THC vapor inhalation effects on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c01a42e2da07f14390ce6755691d4f
https://doi.org/10.1101/2021.09.23.461562
https://doi.org/10.1101/2021.09.23.461562
Autor:
Marcus M. Weera, Nicholas W. Gilpin, Jason W. Middleton, Rosetta S. Shackett, Hannah M. Kramer
Publikováno v:
J Neurosci
Persistent avoidance of stress-related stimuli following acute stress exposure predicts negative outcomes such as substance abuse and traumatic stress disorders. Previous work using a rat model showed that the central amygdala (CeA) plays an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6c7733797a26de6181396ca7502a84
https://europepmc.org/articles/PMC7786206/
https://europepmc.org/articles/PMC7786206/
Autor:
Thomas D. Lobell, Taylor J. Templeton, William B. Snyder, Jason W. Middleton, Tiffany A. Wills, Elizabeth M. Avegno, Michael Constans, Leslie K Kelley, Nicholas W. Gilpin, Chelsea R. Kasten
Publikováno v:
Addict Biol
The neural adaptations that occur during the transition to alcohol dependence are not entirely understood but may include a gradual recruitment of brain stress circuitry by mesolimbic reward circuitry that is activated during early stages of alcohol
Autor:
William B. Snyder, Nicholas W. Gilpin, Taylor J. Templeton, Chelsea R. Kasten, Elizabeth M. Avegno, Michael Constans, Thomas D. Lobell, Tiffany A. Wills, Leslie K Kelley, Jason W. Middleton
The neural adaptations that occur during the transition to alcohol dependence are not entirely understood, but may include a gradual recruitment of brain stress circuitry by mesolimbic reward circuitry that is activated during early stages of alcohol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24a45967ec470c83789b97cc694fc14e
https://doi.org/10.1101/2020.11.02.365445
https://doi.org/10.1101/2020.11.02.365445
Autor:
Jason W. Middleton, Heather L. Cancienne, Patricia E. Molina, Elizabeth A Fucich, Zachary F. Stielper, Scott Edwards, Nicholas W. Gilpin
Publikováno v:
J Neurophysiol
Our previous work showed that lateral fluid percussion injury to the sensorimotor cortex (SMC) of anesthetized rats increased neuronal synaptic hyperexcitability in layer 5 (L5) neurons in ex vivo brain slices 10 days postinjury. Furthermore, endocan