Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jason W. Griffith"'
Autor:
Keshav Nepal, Jason W. Griffith, James J. Moon, Benjamin D. Medoff, Josalyn L. Cho, Rod A. Rahimi, Andrew D. Luster, Daniel L. Hamilos, Lucas Faustino, Dario A. A. Vignali
Publikováno v:
Nature immunology
Cell Mol Immunol
Cell Mol Immunol
Foxp3+ regulatory T (Treg) cells expressing the interleukin (IL)-33 receptor ST2 mediate tissue repair in response to IL-33. Whether Treg cells also respond to the alarmin IL-33 to regulate specific aspects of the immune response is not known. Here w
Autor:
Alicia Franklin, Katharine E. Black, Barry S. Shea, Patricia L. Brazee, Benjamin D. Medoff, Jason W. Griffith, Andreane Cartier, Francesca Giacona, Andrew Kuo, Elizabeth A Abe, Clemens K Probst, Rachel S. Knipe, Matt Drummond, Lida P. Hariri, Christina Christoffersen, Andrew M. Tager, Amanda Logue, Eric Engelbrecht, Sydney B. Montesi, Timothy Hla, Jillian J Spinney
Publikováno v:
Am J Respir Cell Mol Biol
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease which leads to significant morbidity and mortality from respiratory failure. The two drugs currently approved for clinical use slow the rate of decline in lung function but have no
Autor:
R. Scott Harris, Andrew D. Luster, Daniel L. Hamilos, Benjamin D. Medoff, Jasmin A. Holz, Jason W. Griffith, Matthew B. Applegate, Alex Chee, Lida P. Hariri, Margit V. Szabari, Melissa J. Suter, David C. Adams, Josalyn L. Cho, Alyssa J. Miller
Publikováno v:
Respirology. 24:1073-1080
Background and objective In vivo evaluation of the microstructural differences between asthmatic and non-asthmatic airways and their functional consequences is relevant to understanding and, potentially, treating asthma. In this study, we use endobro
Autor:
Kathryn A. Hibbert, Jason W. Griffith, Raghu R. Chivukula, Christopher J. Richards, C. Corey Hardin, Yin P Hung, Daniel Okin, Vladimir Vinarsky, Amy Ly, Jason H. Maley, Camille R. Petri, Alyssa Sclafani, Rebecca A. Israel, Yuval Raz, Angela R. Shih, Mari Mino-Kenudson, Laura N. Brenner, Lida P. Hariri, Alexandra K Wong, Jullian A Villalba, Jonah Rubin, Tiara F. Calhoun, Michael A. Gillette, Jehan Alladina, Benjamin D. Medoff, James R. Stone, Crystal M. North
Publikováno v:
Chest
Background Patients with severe coronavirus disease 2019 (COVID-19) have respiratory failure with hypoxemia and acute bilateral pulmonary infiltrates, consistent with ARDS. Respiratory failure in COVID-19 might represent a novel pathologic entity. Re
Autor:
Fatma Betul Oktelik, Qian Chen, Metin Yusuf Gelmez, Mehdi Benamar, Ayca Kiykim, Ye Cui, Jason Jun Hung Fong, Achille Broggi, Jonathan Z. Li, Sreya Ghosh, Peggy S. Lai, Hani Harb, Murat Kose, Esin Aktas Cetin, Paola Contini, Jason W. Griffith, Ivan Zanoni, Talal A. Chatila, Lorenzo Berra, Elena Crestani, Ziwei Wang, Novalia Pishesha, Klaus Schmitz-Abe, Louis-Marie Charbonnier, Raffaele De Palma, Günnur Deniz, Gilberto Filaci, Emmanuel Stephen-Victor, Stephen C. Kolifrath, Xu G. Yu, Luca Marri, Hidde L. Ploegh, Genny Del Zotto
Publikováno v:
Immunity
Immunity, 2021, 54 (6), pp.1186-1199.e7. ⟨10.1016/j.immuni.2021.04.002⟩
Immunity, 2021, 54 (6), pp.1186-1199.e7. ⟨10.1016/j.immuni.2021.04.002⟩
A cardinal feature of COVID-19 is lung inflammation and respiratory failure. In a prospective multi-country cohort of COVID-19 patients, we found that increased Notch4 expression on circulating regulatory T (Treg) cells was associated with disease se
Autor:
Nicholas J. Rotile, Diego dos Santos Ferreira, Jason W. Griffith, Clemens K. Probst, Peter Caravan, Alexei A. Bogdanov, Aurora Rodríguez-Rodríguez, Sergey Shuvaev, Katherine Graham-O' Regan, Chloe M. Jones, Andrew M. Tager, Rachel S. Knipe, Eszter Boros
Publikováno v:
ACS Sens
An amplifiable magnetic resonance imaging (MRI) probe that combines the stability of the macrocyclic Gd-DOTAGA core with a peroxidase-reactive 5-hydroxytryptamide (5-HT) moiety is reported. The incubation of the complex under enzymatic oxidative cond
Autor:
Jason W. Griffith, Jehan Alladina, Benjamin D. Medoff, Daniel L. Hamilos, K.M. Discipio, Rod A. Rahimi, Josalyn L. Cho, Andrew D. Luster
Publikováno v:
A93. ASTHMA BREAKTHROUGHS: THE ROLE OF THE IMMUNE SYSTEM IN HUMAN ASTHMA.
Publikováno v:
D11. ALL CELLS ON DECK: IMMUNE CELLS AND THE PATHOGENESIS OF LUNG INJURY.
Autor:
Vinidhra Mani, Thorsten R. Mempel, Adam Lacy-Hulbert, Kate L. Jeffrey, Mark A. Travis, Alexandra Y. Chasse, Shannon K. Bromley, Francesco Marangoni, Tarmo Äijö, Ross D. Warner, Craig P. McEntee, Jason W. Griffith, Debattama R. Sen, Moustafa Hamze, Alina Lorant, Rut Mora-Buch, Esteban Carrizosa, Rod A. Rahimi, Andrew D. Luster
Publikováno v:
Science (New York, N.Y.), vol 366, iss 6462
Some naïve T cell fates are sealed Tissue-resident memory T (T RM ) cells constitute a subpopulation of memory cells that reside in tissues instead of recirculating. CD8 + epithelial TRM (eT RM ) cells, which occupy the epithelium of sites like the
Publikováno v:
Annual Review of Immunology. 32:659-702
Chemokines are chemotactic cytokines that control the migratory patterns and positioning of all immune cells. Although chemokines were initially appreciated as important mediators of acute inflammation, we now know that this complex system of approxi