Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Jason W. Chien"'
Autor:
Valerie Williams, Carla DeMuro, Sandy Lewis, Nicole Williams, Todd Wolynn, Paul Wisman, Stan L. Block, Shelly Senders, Seth Toback, Jason W. Chien
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 2, Iss 1, Pp 1-9 (2018)
Abstract Background There are no clinical outcome assessment (COA) tools developed in accordance with Food and Drug Administration (FDA) guidance suitable for the evaluation of symptoms associated with respiratory syncytial virus (RSV) infection amon
Externí odkaz:
https://doaj.org/article/6ebd4ff6880f4feca32408352d5f3c2c
Autor:
Sandy Lewis, Carla DeMuro, Stan L. Block, Shelly Senders, Paul Wisman, Seth Toback, Jason W. Chien, Valerie Williams
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 2, Iss 1, Pp 1-9 (2018)
Abstract Background Respiratory syncytial virus (RSV) is a seasonal infection affecting most children by 2 years of age and the leading cause of lower respiratory tract infection requiring hospitalization in infants. Novel antiviral medications are i
Externí odkaz:
https://doaj.org/article/8dcb8cdb9c544022a54a2396aeabcb47
Autor:
Guang-Shing Cheng, Kristina Crothers, Stefano Aliberti, Anne Bergeron, Michael Boeckh, Jason W. Chien, Catia Cilloniz, Keira Cohen, Nathan Dean, Charles S. Dela Cruz, Robert P. Dickson, Alexander L. Greninger, Chadi A. Hage, Tobias M. Hohl, Steven M. Holland, Barbara E. Jones, Joseph Keane, Mark Metersky, Rachel Miller, Anne Puel, Julio Ramirez, Marcos I. Restrepo, Ajay Sheshadri, Bashar Staitieh, Jeffrey Tarrand, Kevin L. Winthrop, Richard G. Wunderink, Scott E. Evans
Publikováno v:
Annals of the American Thoracic Society. 20:341-353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cf8a364299049d0aec41e78ecf529d4
https://doi.org/10.1513/annalsats.202212-1019st
https://doi.org/10.1513/annalsats.202212-1019st
Autor:
Jens Gottlieb, Fernando Torres, Tarik Haddad, Gundeep Dhillon, Daniel F. Dilling, Christiane Knoop, Reinaldo Rampolla, Rajat Walia, Vivek Ahya, Romain Kessler, Marie Budev, Claus Neurohr, Allan R. Glanville, Robert Jordan, Danielle Porter, Matt McKevitt, Polina German, Ying Guo, Jason W. Chien, Timothy R. Watkins, Martin R. Zamora
Publikováno v:
The Journal of Heart and Lung Transplantation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e535689a72e415e9a65c276ba9976f3c
https://doi.org/10.1016/j.healun.2023.01.013
https://doi.org/10.1016/j.healun.2023.01.013
Autor:
Jason W. Chien, Robert Jordan, Timothy R. Watkins, Ying Guo, Danielle P. Porter, Jason K. Perry, David Gossage
Publikováno v:
Antimicrob Agents Chemother
This study summarizes drug resistance analyses in 4 recent phase 2b trials of the respiratory syncytial virus (RSV) fusion inhibitor presatovir in naturally infected adults. Adult hematopoietic cell transplant (HCT) recipients, lung transplant recipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88e9d1a2d7bae73ada64ef3026ffaed1
https://doi.org/10.1128/aac.02312-19
https://doi.org/10.1128/aac.02312-19
Autor:
Hans H. Hirsch, Danielle P. Porter, Francisco M. Marty, Elodie Blanchard, Jason W. Chien, Polina German, Timothy R. Watkins, Robert Jordan, Sanjeet Dadwal, Roy F. Chemaly, Dong-Gun Lee, Anne Bergeron, Catherine B. Small, Per Ljungman, Matt McKevitt, Alpana Waghmare, Kathleen M. Mullane, Ying Guo, Michael Boeckh, Yae Jean Kim, Shmuel Shoham
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Presatovir significantly reduced nasal viral load, signs, and symptoms of respiratory syncytial virus (RSV) infection in a human challenge study. We evaluated presatovir in hematopoietic-cell transplant (HCT) recipients with RSV lower resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925d922f3424bd6de66df7a76010f5da
http://europepmc.org/articles/PMC7108198
http://europepmc.org/articles/PMC7108198
Autor:
Janet A. Englund, Guang-Shing Cheng, Jessica Yi, Timothy R. Watkins, Wendy M. Leisenring, Sezen Özkök, Alpana Waghmare, Michael Boeckh, Hu Xie, Jason W. Chien, Louise E. Kimball
Publikováno v:
The Journal of Infectious Diseases
Background Clinically meaningful endpoints for respiratory syncytial virus (RSV) treatment trials are lacking for hematopoietic cell transplant (HCT) recipients. We evaluated supplemental oxygen use among HCT recipients with RSV infection. Methods Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d234ee6619c17454340666c7e8cb6b5c
https://doi.org/10.1093/infdis/jix390
https://doi.org/10.1093/infdis/jix390
Autor:
Thomas G. O'Riordan, Jenny Zhang, Emmanuel Moreau, Paul W. Noble, Kevin F. Gibson, Jin Woo Song, Fernando J. Martinez, Victoria Smith, Harold R. Collard, Athol U. Wells, Vincent Cottin, Selina Bayly, Qi Gong, Kevin K. Brown, Ganesh Raghu, Scott D. Patterson, Wim A. Wuyts, Timothy P.M. Whelan, Jason W. Chien, David J. Lederer, Robert J. Kaner
Publikováno v:
The Lancet Respiratory Medicine. 5:22-32
Summary Background Lysyl oxidase-like 2 (LOXL2) catalyses collagen cross-linking and is implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to investigate the efficacy and safety of simtuzumab, a monoclona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12adcfc0f01d42d76dac3c3f04292c8
https://doi.org/10.1016/s2213-2600(16)30421-0
https://doi.org/10.1016/s2213-2600(16)30421-0
Autor:
Kirsten M. Stray, Tomas Cihlar, Michael I. Miller, Michel Perron, Jason W. Chien, Francisco Anderson, Sandra A Lewis, Jason K. Perry, Danielle P. Porter, John P. DeVincenzo, Robert Jordan
Publikováno v:
The Journal of infectious diseases. 222(9)
BackgroundPresatovir is an oral respiratory syncytial virus (RSV) fusion inhibitor targeting RSV F protein. In a double-blind, placebo-controlled study in healthy adults experimentally infected with RSV (Memphis-37b), presatovir significantly reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8251c727142d777e91d9a85488f21c
https://pubmed.ncbi.nlm.nih.gov/31974551
https://pubmed.ncbi.nlm.nih.gov/31974551
Autor:
Roy F. Chemaly, Catherine B. Small, Sanjeet Dadwal, David Gossage, Danielle P. Porter, Polina German, Michael Boeckh, Yae Jean Kim, Ajit P. Limaye, Tsila Zuckerman, Matt McKevitt, Per Ljungman, Guang-Shing Cheng, Jason W. Chien, Roberto L. Patron, Timothy R. Watkins, Hans H. Hirsch, Elodie Blanchard, Dong-Gun Lee, Patrick J. Stiff, Francisco M. Marty, Galia Rahav, Alpana Waghmare, Anne Bergeron, Drew J. Winston, Sudhakar Pipavath, Silvy Lachance, Ying Guo, Robert Jordan, Kathleen M. Mullane
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Hematopoietic-cell transplant (HCT) recipients are at risk for severe respiratory syncytial virus (RSV) infection. We evaluated the RSV fusion inhibitor presatovir in a randomized, double-blind, Phase II trial in HCT recipients with RSV up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555a139a568dfbd3c424002fa8974d12
https://pubmed.ncbi.nlm.nih.gov/31915814
https://pubmed.ncbi.nlm.nih.gov/31915814