Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Jason W. Brown"'
Autor:
Han Wee Ong, Xuan Yang, Jeffery L. Smith, Sharon Taft-Benz, Stefanie Howell, Rebekah J. Dickmander, Tammy M. Havener, Marcia K. Sanders, Jason W. Brown, Rafael M. Couñago, Edcon Chang, Andreas Krämer, Nathaniel J. Moorman, Mark Heise, Alison D. Axtman, David H. Drewry, Timothy M. Willson
Publikováno v:
Molecules, Vol 29, Iss 17, p 4158 (2024)
The host kinase casein kinase 2 (CSNK2) has been proposed to be an antiviral target against β-coronaviral infection. To pharmacologically validate CSNK2 as a drug target in vivo, potent and selective CSNK2 inhibitors with good pharmacokinetic proper
Externí odkaz:
https://doaj.org/article/62c77468b14449aaab38290f68c9e3ba
Autor:
Xuan Yang, Han Wee Ong, Rebekah J. Dickmander, Jeffery L. Smith, Jason W. Brown, William Tao, Edcon Chang, Nathaniel J. Moorman, Alison D. Axtman, Timothy M. Willson
Publikováno v:
ACS Omega, Vol 8, Iss 42, Pp 39546-39561 (2023)
Externí odkaz:
https://doaj.org/article/4d7b606ed5844499b2833820f6af20b2
Autor:
Jason W. Brown
The chapters in this volume attempt to establish some foundational principles of a theory of the mind/brain grounded in evolutionary and process theory. From this standpoint, the book discusses some main problems in philosophical psychology, includin
Autor:
Jason W. Brown
This book is an account of the psychology of romantic love in the context of a theory of emotions. The account develops out of studies in brain psychology and the extension to topics in process-philosophy, such as the nature of value and belief, and
Autor:
Jason W. Brown
The thesis advanced in this book is that feeling and cognition actualize through a process that originates in older brain formations and develops outward through limbic and cortical fields through the self-concept and private space into (as) the worl
Autor:
Jason W. Brown, Maria Pachalska
Publikováno v:
Acta Neuropsychologica. 20:241-253
This paper takes up the problem of agency in relation to freedom. The account is based on the notion that action and perception develop in parallel out of instinctual drive, with thought and imagery pointing to accentuations at pre-perceptual phases,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6764d6edea9cd6f1001987107025e00
https://doi.org/10.5604/01.3001.0015.9443
https://doi.org/10.5604/01.3001.0015.9443
Autor:
Jason W. Brown
Publikováno v:
Neuropsychoanalysis. 22:129-138
This paper is a contribution to a theory of duration and subjective time in dream and waking consciousness. According to microgenetic theory, an act of thought begins, Wittgenstein wrote, and psych...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74856c8f878f54ee6cd4370c1dbf4ee0
https://doi.org/10.1080/15294145.2020.1835527
https://doi.org/10.1080/15294145.2020.1835527
Autor:
Xuan Yang, Rebekah J. Dickmander, Armin Bayati, Sharon A. Taft-Benz, Jeffery L. Smith, Carrow I. Wells, Emily A. Madden, Jason W. Brown, Erik M. Lenarcic, Boyd L. Yount, Edcon Chang, Alison D. Axtman, Ralph S. Baric, Mark T. Heise, Peter S. McPherson, Nathaniel J. Moorman, Timothy M. Willson
Publikováno v:
bioRxiv : the preprint server for biology.
Inhibition of the protein kinase CSNK2 with any of 30 specific and selective inhibitors representing different chemotypes, blocked replication of pathogenic human and murine β-coronaviruses. The potency of in-cell CSNK2A target engagement across the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bd622de1b2d4f231e2e25fae832788
https://pubmed.ncbi.nlm.nih.gov/35723434
https://pubmed.ncbi.nlm.nih.gov/35723434
Autor:
Xuan Yang, Rebekah J. Dickmander, Armin Bayati, Sharon A. Taft-Benz, Jeffery L. Smith, Carrow I. Wells, Emily A. Madden, Jason W. Brown, Erik M. Lenarcic, Boyd L. Yount, Edcon Chang, Alison D. Axtman, Ralph S. Baric, Mark T. Heise, Peter S. McPherson, Nathaniel J. Moorman, Timothy M. Willson
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 3
article-version (status) pre
article-version (number) 3
Inhibition of the protein kinase CSNK2 with any of 30 specific and selective inhibitors representing different chemotypes, blocked replication of pathogenic human and murine β-coronaviruses. The potency of in-cell CSNK2A target engagement across the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc35b8d18d3437b057697dea428a8e3
Autor:
Todd Macklin, Mark Carlton, Hopkins Maria, Stephen Hitchcock, Hans H Schiffer, Deanna R Collia, Steve Moore, Kikuchi Shota, Nicole Marion English, Mark L. Adams, Murphy Sean, William J. Ray, Jason Green, Jason W. Brown, Holger Monenschein, Huikai Sun, Nicola Brice, Holly Reichard, Nidhi Kaushal
Publikováno v:
Journal of medicinal chemistry. 64(14)
Parkinson's disease (PD) is a chronic and progressive movement disorder with the urgent unmet need for efficient symptomatic therapies with fewer side effects. GPR6 is an orphan G-protein coupled receptor (GPCR) with highly restricted expression in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a916c19bb4b6311dc8964de6bf626764
https://pubmed.ncbi.nlm.nih.gov/33861086
https://pubmed.ncbi.nlm.nih.gov/33861086