Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jason W. Ashley"'
Publikováno v:
PeerJ, Vol 11, p e14814 (2023)
Background Sex is an important risk factor in the development of osteoporosis and other bone loss disorders, with women often demonstrating greater susceptibility than men. While variation in sex steroids, such as estradiol, accounts for much of the
Externí odkaz:
https://doaj.org/article/6d989ba88b504661844e59616b6a0e91
Autor:
Sasanka Ramanadham, Tomader Ali, Jason W. Ashley, Robert N. Bone, William D. Hancock, Xiaoyong Lei
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 9, Pp 1643-1668 (2015)
Among the family of phospholipases A2 (PLA2s) are the Ca2+-independent PLA2s (iPLA2s) and they are designated group VI iPLA2s. In relation to secretory and cytosolic PLA2s, the iPLA2s are more recently described and details of their expression and ro
Externí odkaz:
https://doaj.org/article/21e6391acba34f2581abdc148f3fed1f
Autor:
Jaimo Ahn, Peeyush N. Goel, Yasaman Moharrer, Alexander J. Egol, Jason W. Ashley, Beatrix Brandfield-Harvey
Publikováno v:
Biochem Biophys Res Commun
Chronic inflammatory responses have profound effects on the differentiation and activity of both the bone-forming osteoblasts and bone-resorbing osteoclasts. Importantly, inflammatory bone diseases characterized by clinical osteolysis promote bone re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2e4a534cc3befa1a8dc2e7458a3541
https://doi.org/10.1016/j.bbrc.2019.05.166
https://doi.org/10.1016/j.bbrc.2019.05.166
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25838 (2011)
CD68 is a member of the lysosome associated membrane protein (LAMP) family that is restricted in its expression to cells of the monocyte/macrophage lineage. This lineage restriction includes osteoclasts, and, while previous studies of CD68 in macroph
Externí odkaz:
https://doaj.org/article/756a2d47509d46cfbe4c873c24d7fed6
Autor:
John H. Hebb, Kurt D. Hankenson, Peeyush N. Goel, Jason W. Ashley, Yasaman Moharrer, Jaimo Ahn, Alexander J. Egol, Gurpreet Kaur
Publikováno v:
J Orthop Res
Owing to the central role of osteoclasts in bone physiology and remodeling, manipulation of their maturation process provides a potential therapeutic strategy for treating bone diseases. To investigate this, we genetically inhibited the Notch signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba003b1b5be1e223e6b847e6017dd710
https://pubmed.ncbi.nlm.nih.gov/31166033
https://pubmed.ncbi.nlm.nih.gov/31166033
Autor:
Lachlan J. Smith, Yejia Zhang, Daniel W. Chan, Robert L. Mauck, Howard S. An, Martin F. Heyworth, Joseph Lee, Jason W. Ashley, Motomi Enomoto-Iwamoto
Publikováno v:
Genes & Diseases. 3:171-177
The intervertebral disc (IVD) comprises a gelatinous inner core (nucleus pulposus; NP) and concentric rings (annulus fibrosus; AF). The NP, an important structure for shock absorption in the vertebrate spinal motion segment, can be traced back to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb08dab3bf2865ea73cef1fbaf58052
https://doi.org/10.1016/j.gendis.2016.04.006
https://doi.org/10.1016/j.gendis.2016.04.006
Autor:
Kurt D. Hankenson, Robert L. Zondervan, Alekos A. Theologis, Chelsea S. Bahney, Theodore Miclau, Jason W. Ashley, Ralph S. Marcucio, Jaimo Ahn, Patrick Allison
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, vol 37, iss 1
The biology of bone healing is a rapidly developing science. Advances in transgenic and gene-targeted mice have enabled tissue and cell-specific investigations of skeletal regeneration. As an example, only recently has it been recognized that chondro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ca19e886d24b3dfe804f62cc94fb71
https://europepmc.org/articles/PMC6542569/
https://europepmc.org/articles/PMC6542569/
Autor:
Zuozhen Tian, Yulong Wei, Shuying Yang, Luqiang Wang, Robert J. Tower, Yejia Zhang, Motomi Enomoto-Iwamoto, Jason W. Ashley, Ling Qin
Publikováno v:
Am J Phys Med Rehabil
OBJECTIVE: The aim of the study was to determine the transcription profile of the mouse nucleus pulposus and annulus fibrosus with an unbiased method. Furthermore, pathophysiological relevance of selected genes was demonstrated in the mouse tail inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18e4b975e40293e592e246143970903
https://pubmed.ncbi.nlm.nih.gov/30085932
https://pubmed.ncbi.nlm.nih.gov/30085932
Publikováno v:
Alagille Syndrome ISBN: 9783319945705
Alagille syndrome results in a spectrum of skeletal abnormalities in patients. Distinct facies are pathognomonic for the disease, and butterfly vertebrae are common. Patients have reduced bone mass and a propensity to fracture. While some of these ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff1992be510a82751ab3d478e4678ae3
https://doi.org/10.1007/978-3-319-94571-2_9
https://doi.org/10.1007/978-3-319-94571-2_9
Autor:
Xiaoyong Lei, Tomader Ali, Jason W. Ashley, Sasanka Ramanadham, William D. Hancock, Robert N. Bone
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 9, Pp 1643-1668 (2015)
Among the family of phospholipases A2 (PLA2s) are the Ca(2+)-independent PLA2s (iPLA2s) and they are designated group VI iPLA2s. In relation to secretory and cytosolic PLA2s, the iPLA2s are more recently described and details of their expression and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273f55e2d524e846e5bcbab7db0bba8e
https://doi.org/10.1194/jlr.r058701
https://doi.org/10.1194/jlr.r058701