Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jason W Reeves"'
Autor:
Annegien Broeks, Ines Pires da Silva, Sarah Warren, Pia Kvistborg, Georgina V Long, Richard A Scolyer, Christian U Blank, Esmee P Hoefsmit, Elisa A Rozeman, Trieu My Van, Petros Dimitriadis, Jordan W Conway, Jacqueline E van der Wal, Steven L C Ketelaars, Kaspar Bresser, Ron M Kerkhoven, Jason W Reeves, Ellen W Kapiteijn, Ton N M Schumacher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The profound disparity in response to immune checkpoint blockade (ICB) by cutaneous melanoma (CM) and uveal melanoma (UM) patients is not well understood. Therefore, we characterized metastases of CM and UM from the same metastatic site (l
Externí odkaz:
https://doaj.org/article/57566697358f40ef905dd40c8195aef6
Autor:
Brankica Mravinac, Lori L Sullivan, Jason W Reeves, Christopher M Yan, Kristen S Kopf, Christine J Farr, Mary G Schueler, Beth A Sullivan
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6602 (2009)
Human centromeres are multi-megabase regions of highly ordered arrays of alpha satellite DNA that are separated from chromosome arms by unordered alpha satellite monomers and other repetitive elements. Complexities in assembling such large repetitive
Externí odkaz:
https://doaj.org/article/ee4563d4506e4999bfbc6e80983bf9c6
Autor:
William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Carina Shiau, Jennifer Su, Payman Yadollahpour, Jason W. Reeves, Youngmi Kim, Sean Kim, Mark Gregory, Prajan Divakar, Eric Miller, Michael Rhodes, Sarah Warren, Erroll Rueckert, Kit Fuhrman, Daniel R. Zollinger, Robin Fropf, Joseph M. Beechem, Arnav Mehta, Toni Delorey, Cristin McCabe, Jaimie L. Barth, Piotr Zelga, Cristina R. Ferrone, Motaz Qadan, Keith D. Lillemoe, Rakesh K. Jain, Jennifer Y. Wo, Theodore S. Hong, Ramnik Xavier, Orit Rozenblatt-Rosen, Andrew J. Aguirre, Carlos Fernandez-Del Castillo, Andrew S. Liss, Mari Mino-Kenudson, David T. Ting, Tyler Jacks, Aviv Regev
Publikováno v:
Cancer Research. 82:SY12-04
Pancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer mortality in the United States by 2030. Given that resistance to cytotoxic therapy is pervasive, there is a critical need to elucidate salient gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b0a63ea71b261143c84d7a7f0f567e9
https://doi.org/10.1158/1538-7445.am2022-sy12-04
https://doi.org/10.1158/1538-7445.am2022-sy12-04
Autor:
William L. Hwang, Karthik A. Jagadeesh, Jimmy A. Guo, Hannah I. Hoffman, Payman Yadollahpour, Jason W. Reeves, Rahul Mohan, Eugene Drokhlyansky, Nicholas Van Wittenberghe, Orr Ashenberg, Samouil L. Farhi, Denis Schapiro, Prajan Divakar, Eric Miller, Daniel R. Zollinger, George Eng, Jason M. Schenkel, Jennifer Su, Carina Shiau, Patrick Yu, William A. Freed-Pastor, Domenic Abbondanza, Arnav Mehta, Joshua Gould, Conner Lambden, Caroline B. M. Porter, Alexander Tsankov, Danielle Dionne, Julia Waldman, Michael S. Cuoco, Lan Nguyen, Toni Delorey, Devan Phillips, Jaimie L. Barth, Marina Kem, Clifton Rodrigues, Debora Ciprani, Jorge Roldan, Piotr Zelga, Vjola Jorgji, Jonathan H. Chen, Zackery Ely, Daniel Zhao, Kit Fuhrman, Robin Fropf, Joseph M. Beechem, Jay S. Loeffler, David P. Ryan, Colin D. Weekes, Cristina R. Ferrone, Motaz Qadan, Martin J. Aryee, Rakesh K. Jain, Donna S. Neuberg, Jennifer Y. Wo, Theodore S. Hong, Ramnik Xavier, Andrew J. Aguirre, Orit Rozenblatt-Rosen, Mari Mino-Kenudson, Carlos Fernandez-del Castillo, Andrew S. Liss, David T. Ting, Tyler Jacks, Aviv Regev
Publikováno v:
Nat Genet
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet inform clinical management or therapeutic development. Here, we construct a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52fea7e3e72f452826d1f68df747811
https://europepmc.org/articles/PMC10290535/
https://europepmc.org/articles/PMC10290535/
Autor:
Carina Shiau, Jingyi Cao, Mark Gregory, Tae Kyung Kim, Youngmi Kim, Jason W. Reeves, Peter L. Wang, Steven Wang, Nicole A. Lester, Jennifer Su, Jimmy Guo, Joseph M. Beechem, David T. Ting, Martin Hemberg, William L. Hwang
Publikováno v:
Cancer Research. 83:1165-1165
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a 5-year survival rate of 11%. PDAC has limited response to current cytotoxic, targeted and immunotherapies. Thus, it is crucial to explore the molecular underpinnings of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fadd87db99a5168782d86fc9225f3fb
https://doi.org/10.1158/1538-7445.am2023-1165
https://doi.org/10.1158/1538-7445.am2023-1165
Autor:
Shanshan He, Michael Patrick, Jason W. Reeves, Patrick Danaher, Julian Preciado, Joseph Phan, Erin Piazza, Zachary Reitz, Lidan Wu, Rustem Khafizov, Haiyan Zhai, Michael Rhodes, David Ruff, Joseph Beechem
Publikováno v:
Cancer Research. 83:5637-5637
Cancer research across drug development, molecular biomarkers, and patient response depends on understanding biology that is dependent on complex interactions between malignant, immune, and stromal cells. To survive clearance mechanisms, a tumor can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdf63a98a72a661106984b353128680f
https://doi.org/10.1158/1538-7445.am2023-5637
https://doi.org/10.1158/1538-7445.am2023-5637
Autor:
William L. Hwang, Jennifer Su, Carina Shiau, Peter L. Wang, Jimmy A. Guo, Nicole A. Lester, Jaimie L. Barth, Hannah I. Hoffman, Prajan Divakar, Jason W. Reeves, Eric Miller, Joseph M. Beechem, Andrew J. Aguirre, Lei Zheng, David T. Ting, Mari Mino-Kenudson, Tyler Jacks
Publikováno v:
Cancer Research. 83:2513-2513
Pancreatic ductal adenocarcinoma (PDAC) features abundant perineural invasion (PNI). Intra-tumoral nerves play critical roles in cancer initiation, progression, recurrence, treatment-resistance, metastasis, and mortality for many malignancies but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8039a175bc8bcdf47d39e3669e9fd5b5
https://doi.org/10.1158/1538-7445.am2023-2513
https://doi.org/10.1158/1538-7445.am2023-2513
Autor:
Jason W. Reeves, Esperanza Anguiano, Vikram Devgan, Nicholas Confuorto, Joachim Schmid, Yan Liang, Joseph Beechem
Publikováno v:
Cancer Research. 83:985-985
Biomarker development in the clinical trial setting is frequently limited by the availability of small tissue specimens, such as core needle biopsies. To enable forward and reverse translational assays to best understand patient-specified biomarkers,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fba55f43fc8e913c0b94feb477d559a
https://doi.org/10.1158/1538-7445.am2023-985
https://doi.org/10.1158/1538-7445.am2023-985
Autor:
Claire Williams, Jason W. Reeves, Patrick Danaher, Shanshan He, Sean Kim, Michael Patrick, Julian Preciado, Mark Gregory, Zach Reitz, Justin Jenkins, Rachel Liu, Sarah Murphy, Christine Kang, Byron Hartman, Vikram Devgan, Michael Rhodes, Joseph Beechem
Publikováno v:
Cancer Research. 83:6765-6765
Patient response to immunotherapy has been revolutionary but remains limited due to the inability to convert excluded or cold tumors into ones which would be permissive to therapeutic intervention. To treat patients that evade immune therapy, compreh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8968dcfd795aef89f3902037189a1eb3
https://doi.org/10.1158/1538-7445.am2023-6765
https://doi.org/10.1158/1538-7445.am2023-6765
Publikováno v:
Cancer Research. 83:2083-2083
Spatial biology is revolutionizing the way in which we extract biological insights from precious clinical samples, allowing profiling of thousands of RNA species and ever higher numbers of antibodies to be analyzed from a single tissue slide. But wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82bb5907ad3384b42b0e1e88e295ab54
https://doi.org/10.1158/1538-7445.am2023-2083
https://doi.org/10.1158/1538-7445.am2023-2083