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pro vyhledávání: '"Jason V. Rogers"'
Autor:
Nathaniel H. Thayer, Michael Robles, Jun Xu, Elizabeth L. Schinski, Manuel Hotz, Robert Keyser, Alfred Millett-Sikking, Voytek Okreglak, Jason V. Rogers, Adam J. Waite, Bernd J. Wranik, Andrew G. York, R. Scott McIsaac, Daniel E. Gottschling
SummaryThe budding yeast, Saccharomyces cerevisiae, has emerged as a model system for studying the aging processes in eukaryotic cells. However, the full complement of tools available in this organism has not been fully applied, in part because of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::911620ff6fc9c8d9976a478b2fc7f600
https://doi.org/10.1101/2022.02.14.480146
https://doi.org/10.1101/2022.02.14.480146
Autor:
Rebecca Y Wang, Jason V. Rogers, Maria Ingaramo, R. Scott McIsaac, Alisha G Lewis, Ilya Soifer, Patrick A. Gibney, David G. Hendrickson, Robert L. Caldwell, David Botstein
Publikováno v:
Molecular Biology of the Cell. 32
The electron transport chain (ETC) is a well-studied and highly conserved metabolic pathway that produces ATP through generation of a proton gradient across the inner mitochondrial membrane coupled to oxidative phosphorylation. ETC mutations are asso
Autor:
Mark D. Rose, Jason V. Rogers
Publikováno v:
G3: Genes|Genomes|Genetics
During mating in the budding yeast Saccharomyces cerevisiae, two haploid nuclei fuse via two sequential membrane fusion steps. SNAREs (i.e., soluble N-ethylmaleimide–sensitive factor attachment protein receptors) and Prm3p mediate outer nuclear mem
Publikováno v:
Molecular Biology of the Cell
SNAREs and the Dsl1 complex mediate an alternative, Sey1p-independent homotypic endoplasmic reticulum (ER) fusion pathway in yeast. When both pathways and the reticulons are simultaneously disrupted, cells are inviable. This demonstrates that homotyp
Publikováno v:
Molecular Biology of the Cell
Both SNAREs and Sey1p are required for efficient nuclear fusion during yeast mating. SNAREs appear to act at the step of nuclear envelope fusion, whereas Sey1p remodels the ER network to permit nuclear congression. In addition, SNARE sey1Δ double mu
Publikováno v:
The EMBO Journal. 30:2990-3003
Epidermal growth factor (EGF) signalling regulates growth and differentiation. Here, we examine the function of EGF signalling in Caenorhabditis elegans lifespan. We find that EGF signalling regulates lifespan via the Ras-MAPK pathway and the PLZF tr