Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jason Uslaner"'
Autor:
Ditte Lovatt, Alex Tamburino, Alicja Krasowska-Zoladek, Raul Sanoja, Lixia Li, Vanessa Peterson, Xiaohai Wang, Jason Uslaner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Single-cell RNA-seq analysis of naive and injured sensory nerves in a rat model provide further insight into the molecular pathways underlying nerve injury, regeneration, and repair.
Externí odkaz:
https://doaj.org/article/2edeb25a77a54bae9f35252186d3da78
Autor:
Wenping, Li, Yuchuan, Wang, Talakad G, Lohith, Zhizhen, Zeng, Ling, Tong, Robert, Mazzola, Kerry, Riffel, Patricia, Miller, Mona, Purcell, Marie, Holahan, Hyking, Haley, Liza, Gantert, David, Hesk, Sumei, Ren, John, Morrow, Jason, Uslaner, Arie, Struyk, Jenny Miu-Chun, Wai, Michael T, Rudd, David M, Tellers, Thomas, McAvoy, Guy, Bormans, Michel, Koole, Koen, Van Laere, Kim, Serdons, Jan, de Hoon, Ruben, Declercq, Inge, De Lepeleire, Maria B, Pascual, Paolo, Zanotti-Fregonara, Meixiang, Yu, Victoria, Arbones, Joseph C, Masdeu, Amy, Cheng, Azher, Hussain, Tjerk, Bueters, Matt S, Anderson, Eric D, Hostetler, Anthony S, Basile
Publikováno v:
Science translational medicine. 14(627)
Positron emission tomography (PET) ligands play an important role in the development of therapeutics by serving as target engagement or pharmacodynamic biomarkers. Here, we describe the discovery and translation of the PET tracer [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4a48387c373777e91d8509feb8c9c29
https://pubmed.ncbi.nlm.nih.gov/35020407
https://pubmed.ncbi.nlm.nih.gov/35020407
Autor:
Wenping Li, Yuchuan Wang, Talakad G. Lohith, Zhizhen Zeng, Ling Tong, Robert Mazzola, Kerry Riffel, Patricia Miller, Mona Purcell, Marie Holahan, Hyking Haley, Liza Gantert, David Hesk, Sumei Ren, John Morrow, Jason Uslaner, Arie Struyk, Jenny Miu-Chun Wai, Michael T. Rudd, David M. Tellers, Thomas McAvoy, Guy Bormans, Michel Koole, Koen Van Laere, Kim Serdons, Jan de Hoon, Ruben Declercq, Inge De Lepeleire, Maria B. Pascual, Paolo Zanotti-Fregonara, Meixiang Yu, Victoria Arbones, Joseph C. Masdeu, Amy Cheng, Azher Hussain, Tjerk Bueters, Matt S. Anderson, Eric D. Hostetler, Anthony S. Basile
Positron emission tomography (PET) ligands play an important role in the development of therapeutics by serving as target engagement or pharmacodynamic biomarkers. Here, we describe the discovery and translation of the PET tracer [11C]MK-6884 from rh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e44197a5317a5a2a9f28fb0766d601b
https://lirias.kuleuven.be/handle/20.500.12942/688229
https://lirias.kuleuven.be/handle/20.500.12942/688229
Autor:
Sean Smith, Jason Uslaner, Monika Kandebo, Eric Hostetler, Izzat Raheem, Mark Layton, Liza Gantert, Kerry Riffel, Christopher Cox, Sauzanne Khalilieh, Inge De Lepeleire, Guy Bormans, Marleen Depré, Jan de Hoon, Koen Van Laere
Publikováno v:
Biological Psychiatry. 91:S309-S310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be24d4d168d91f8a0c44a7922f62e58c
https://doi.org/10.1016/j.biopsych.2022.02.783
https://doi.org/10.1016/j.biopsych.2022.02.783
Autor:
Ling, Tong, Wenping, Li, Michael Man-Chu, Lo, Xiaolei, Gao, Jenny Miu-Chen, Wai, Michael, Rudd, David, Tellers, Aniket, Joshi, Zhizhen, Zeng, Patricia, Miller, Cristian, Salinas, Kerry, Riffel, Hyking, Haley, Mona, Purcell, Marie, Holahan, Liza, Gantert, Jeffrey W, Schubert, Kristen, Jones, James, Mulhearn, Melissa, Egbertson, Zhaoyang, Meng, Barbara, Hanney, Robert, Gomez, Scott T, Harrison, Paul, McQuade, Tjerk, Bueters, Jason, Uslaner, John, Morrow, Fiona, Thomson, Jongrock, Kong, Jing, Liao, Oleg, Selyutin, Jianming, Bao, Nicholas B, Hastings, Sony, Agrawal, Brian C, Magliaro, Frederick J, Monsma, Michelle D, Smith, Stefania, Risso, David, Hesk, Eric, Hostetler, Robert, Mazzola
Publikováno v:
Journal of medicinal chemistry. 63(5)
The measurement of receptor occupancy (RO) using positron emission tomography (PET) has been instrumental in guiding discovery and development of CNS directed therapeutics. We and others have investigated muscarinic acetylcholine receptor 4 (M4) posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd3ef3c047c980065bd64efde0a0b7e9
https://pubmed.ncbi.nlm.nih.gov/32101422
https://pubmed.ncbi.nlm.nih.gov/32101422
Autor:
Jeffrey W, Schubert, Scott T, Harrison, James, Mulhearn, Robert, Gomez, Robert, Tynebor, Kristen, Jones, Jaime, Bunda, Barbara, Hanney, Jenny Miu-Chen, Wai, Chris, Cox, John A, McCauley, John M, Sanders, Brian, Magliaro, Julie, O'Brien, Natasa, Pajkovic, Sarah L, Huszar Agrapides, Anne, Taylor, Anthony, Gotter, Sean M, Smith, Jason, Uslaner, Susan, Browne, Stefania, Risso, Melissa, Egbertson
Publikováno v:
ChemMedChem. 14(9)
Herein we describe the discovery and optimization of a new series of 2,3-disubstituted and 2,3,6-trisubstituted muscarinic acetylcholine receptor 4 (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::475ab82d66001ed942e40ff31fcd1945
https://pubmed.ncbi.nlm.nih.gov/30920765
https://pubmed.ncbi.nlm.nih.gov/30920765
Autor:
Jason, Uslaner, Badiani, Aldo, Norton, Camille S., Day, Heidi E. W., Watson, Stanley J., Huda, Akil, Robinson, Terry E.
Publikováno v:
The European journal of neuroscience. 13(10)
In the dorsal striatum, there are two major populations of medium spiny projection neurons. One population is positive for dynorphin mRNA (DYN+), and these cells project preferentially to the substantia nigra, forming the so-called 'direct pathway'.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50d3f8f5a345ee4e8b4f5d3cba3b0c5b
https://pubmed.ncbi.nlm.nih.gov/11403691
https://pubmed.ncbi.nlm.nih.gov/11403691