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pro vyhledávání: '"Jason Terry Sanderson"'
Autor:
James W. Leahy, Shouming Wang, Michael P. Prisbylla, Morrison B. Mac, Nigel Vicker, Patrick Kearney, Golec Julian M C, Robert R. Webb, David A. Matthews, Reyna J. Simon, Art Hanel, Richard Faint, Jason Terry Sanderson, Erin Engelhardt, S. David Brown, Peter Charlton, Lynne Canne, Jocelyn Chan, Sergey Epshteyn, Adrian Folkes, Zerom Tesfai
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(7)
We have synthesized and evaluated a series of tetramic acid-based and hydroxyquinolinone-based inhibitors of plasminogen activator inhibitor-1 (PAI-1). These studies resulted in the identification of several compounds which showed excellent potency a