Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jason T. White"'
Autor:
Mitra Ashayeripanah, Javier Vega-Ramos, Daniel Fernandez-Ruiz, Shirin Valikhani, Aaron T.L. Lun, Jason T. White, Louise J. Young, Atefeh Yaftiyan, Yifan Zhan, Linda Wakim, Irina Caminschi, Mireille H. Lahoud, Andrew M. Lew, Ken Shortman, Gordon K. Smyth, William R. Heath, Justine D. Mintern, Antoine Roquilly, Jose A. Villadangos
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113754- (2024)
Summary: Blood-borne pathogens can cause systemic inflammatory response syndrome (SIRS) followed by protracted, potentially lethal immunosuppression. The mechanisms responsible for impaired immunity post-SIRS remain unclear. We show that SIRS trigger
Externí odkaz:
https://doaj.org/article/531a91054c1e4bb68aeda10b35050804
Autor:
Jason T. White, Eric W. Cross, Matthew A. Burchill, Thomas Danhorn, Martin D. McCarter, Hugo R. Rosen, Brian O’Connor, Ross M. Kedl
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Virtual memory T cells are CD8 T cells with memory phenotype present in unimmunized mice. Here the authors show that these cells have higher affinity for self-antigen, depend on IL-15 for proliferation and antigen-non-specific cytotoxicity in mice, a
Externí odkaz:
https://doaj.org/article/5b504adf9a774808aa2014fe7ae6ebee
Publikováno v:
Nature Reviews Immunology. 17:391-400
In this Opinion article, the authors discuss our growing appreciation of antigen-inexperienced memory T cell subsets. They focus on the development and functions of the recently described 'virtual memory' and 'innate memory' CD8+T cell populations, a
Autor:
Jason T. White, Ross M. Kedl
Publikováno v:
Nature Reviews Immunology. 18:1-1
Memory-phenotype CD8+ T cells exist in substantial numbers within hosts that have not been exposed to either foreign antigen or overt lymphopenia. These antigen-inexperienced memory-phenotype T cells can be divided into two major subsets: ‘innate m
Autor:
Jason T. White, Matthew A. Burchill, Martin D. McCarter, Brian P. O'Connor, Thomas Danhorn, Hugo R. Rosen, Eric W. Cross, Ross M. Kedl
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Virtual memory cells (VM) are an antigen-specific, memory phenotype CD8 T-cell subset found in lymphoreplete, unchallenged mice. Previous studies indicated that VM cells were the result of homeostatic proliferation (HP) resembling the proliferation o
Autor:
J. Patrick McLaughlin, Jason T. White
Publikováno v:
Journal of Business Case Studies (JBCS). 2:19-22
The purpose of this case study is to discuss the feasibility of a business incubation facility in an agricultural region of the United States. The paper explains some of the unique characteristics of this environment, and discusses what an incubator
Autor:
Eric W. Cross, Elizabeth E. Cheney, Beth A. Jirón Tamburini, Ross M. Kedl, Jason T. White, Nathan D. Pennock
Publikováno v:
Advances in physiology education. 37(4)
THE MAMMALIAN IMMUNE SYSTEM can be broadly divided into two main arms: innate and adaptive immunity. As its name implies, the cells and receptors of the innate immune system are critical for the rapid recognition of the infectious agent and initiatin
Autor:
Jason T. White, Ross M. Kedl, Philippa Marrack, Catherine Haluszczak, Eric W. Cross, Laurent Gapin, Tomasz Sosinowski
Various populations of memory phenotype CD8+ T cells have been described over the last 15–20 y, all of which possess elevated effector functions relative to naive phenotype cells. Using a technique for isolating Ag-specific cells from unprimed host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e6df414d30b2c861086a5c265ae054
https://europepmc.org/articles/PMC3578102/
https://europepmc.org/articles/PMC3578102/
Autor:
Beth A. Jirón Tamburini, Jonathan S. Kurche, Matthew A. Burchill, Ross M. Kedl, Nathan D. Pennock, Jason T. White
Publikováno v:
Vaccine. 31(2)
The objective of modern vaccine development is the safe generation of protective long-term immune memory, both prophylactic and therapeutic. Live attenuated vaccines generate potent cellular and humoral immunity [1–3], but numerous problems exist w
Autor:
Benjamin A. Winston, Darell D. Bigner, Rae L. Russell, Nathaniel L. Dusto, Rebecca D. Dodd, Jason T. White, Alex M. Lencioni, Matthew Herring, Helen Madsen, Laura M. Epple, Christopher V. Nicchitta, Meheret Nega, Andrea L. Merz, Michael W. Graner, Natalie J. Serkova, Anjelika Dechkovskaia
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e73267 (2013)
PLoS ONE, Vol 8, Iss 8, p e73267 (2013)
The unfolded protein response (UPR) is an endoplasmic reticulum (ER)-based cytoprotective mechanism acting to prevent pathologies accompanying protein aggregation. It is frequently active in tumors, but relatively unstudied in gliomas. We hypothesize