Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jason T. Sengel"'
Autor:
Kozhinjampara R. Mahendran, William M. Dawson, Mark I. Wallace, Jason T. Sengel, Adrian J. Mulholland, William F. DeGrado, Hagan Bayley, Lijun Liu, R. Leo Brady, Eric J. M. Lang, Ai Niitsu, Alistair J. Scott, Derek N. Woolfson, Marco Mravic, Andrew R. Thomson, Huong T. Kratochvil
Publikováno v:
Scott, A J, Niitsu, A, Lang, E J M, Dawson, W M, Brady, R L, Mulholland, A J & Woolfson, D N 2021, ' Constructing ion channels from water-soluble α-helical barrels ', Nature Chemistry, vol. 13, no. 7, pp. 643-650 . https://doi.org/10.1038/s41557-021-00688-0
The design of peptides that assemble in membranes to form functional ion channels is challenging. Specifically, hydrophobic interactions must be designed between the peptides and at the peptide–lipid interfaces simultaneously. Here, we take a multi
Publikováno v:
Sustainable Energy & Fuels. 4:3388-3399
Thermogalvanic cells typically utilise equimolar concentrations of the oxidised and reduced states of a redox couple in solution, sandwiched between two electrodes at dissimilar temperatures; entropy drives redox processes to occur at these electrode
Publikováno v:
Green Chemistry. 22:6062-6074
Thermogalvanic cells can act like ‘liquid thermoelectrics’ to convert a thermal energy gradient to electrical energy. Such cells are typically combined electrically in-series in devices to boost the output voltage (as thermocells). However, the t
Autor:
Alistair J, Scott, Ai, Niitsu, Huong T, Kratochvil, Eric J M, Lang, Jason T, Sengel, William M, Dawson, Kozhinjampara R, Mahendran, Marco, Mravic, Andrew R, Thomson, R Leo, Brady, Lijun, Liu, Adrian J, Mulholland, Hagan, Bayley, William F, DeGrado, Mark I, Wallace, Derek N, Woolfson
Publikováno v:
Nature chemistry. 13(7)
The design of peptides that assemble in membranes to form functional ion channels is challenging. Specifically, hydrophobic interactions must be designed between the peptides and at the peptide-lipid interfaces simultaneously. Here, we take a multi-s
Autor:
Mark I. Wallace, Jason T. Sengel
Publikováno v:
Sengel, J T & Wallace, M I 2016, ' Imaging the dynamics of individual electropores ', Proceedings of the National Academy of Sciences, vol. 113, no. 19, pp. 5281-5286 . https://doi.org/10.1073/pnas.1517437113
Electroporation is a widely used technique to permeabilize cell membranes. Despite its prevalence, our understanding of the mechanism of voltage-mediated pore formation is incomplete; methods capable of visualizing the time-dependent behavior of indi
Autor:
Mark I. Wallace, Jason T. Sengel
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 372(1726)
Electroporation is a common tool for gene transfection, tumour ablation, sterilization and drug delivery. Using experimental methods, we explore the temperature dependence of electropore formation in a model membrane system (droplet-interface bilayer
Autor:
Jennifer E, Jones, Vincent, Diemer, Catherine, Adam, James, Raftery, Rebecca E, Ruscoe, Jason T, Sengel, Mark I, Wallace, Antoine, Bader, Scott L, Cockroft, Jonathan, Clayden, Simon J, Webb
Publikováno v:
Journal of the American Chemical Society
The synthetic biology toolbox lacks extendable and conformationally controllable yet easy-to-synthesize building blocks that are long enough to span membranes. To meet this need, an iterative synthesis of α-aminoisobutyric acid (Aib) oligomers was u
Publikováno v:
Biophysical Journal. (2):502a
We report a method to visualize individual potential-mediated defects in planar Droplet Interface Bilayers using Total Internal Reflection Fluorescence microscopy. Optical Single Channel Recordings of ionic flux across the bilayer enables us to chara