Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jason T. Ross"'
Autor:
Tracey Williams, Rajendran Vairagoundar, Julie A. White, Dennis L Huczek, Respondek Tomasz, Jason T. Ross, Johnson Paul D, Carolyn Hedke, Andrea J Gonzales, Govindan Subramanian, Christopher Javens, Todd Maddux, Brian A. Duclos, Theresa Zachary, Mark R Cox, Wendy Collard, Yaqi Zhu, Steven Kamerling, Scott J. Bowen
Publikováno v:
ACS Medicinal Chemistry Letters. 12:1847-1852
Human β-nerve growth factor (β-NGF) and its associated receptor, human tropomyosin receptor kinase A (hTrkA), have been demonstrated to be key factors in the perception of pain. However, efficacious small molecule therapies targeting the intracellu
Autor:
Govindan, Subramanian, Brian, Duclos, Paul D, Johnson, Tracey, Williams, Jason T, Ross, Scott J, Bowen, Yaqi, Zhu, Julie A, White, Carolyn, Hedke, Dennis, Huczek, Wendy, Collard, Christopher, Javens, Rajendran, Vairagoundar, Tomasz, Respondek, Theresa, Zachary, Todd, Maddux, Mark R, Cox, Steven, Kamerling, Andrea J, Gonzales
Publikováno v:
ACS Med Chem Lett
[Image: see text] Human β-nerve growth factor (β-NGF) and its associated receptor, human tropomyosin receptor kinase A (hTrkA), have been demonstrated to be key factors in the perception of pain. However, efficacious small molecule therapies target
Autor:
C A Rugg, S Alexander-Bowman, Brian A. Duclos, Jason T. Ross, Curry James Taylor, Steven Kamerling, C Chio, A Townley, Dennis L Huczek, Julie A. White, M Darling, D Garcia-Tapia
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 40:70-76
The effects of a selective bradykinin 1 receptor antagonist, compound A, were evaluated in a canine model of acute inflammatory model of arthritis. Despite detection of the B1 receptor in canine type B synoviocytes using a fluorescent ligand, oral ad
Autor:
Suguru Koyama, Joshua Levitt, Steven Kamerling, Carl Y. Saab, Adam Z. Nitenson, Curry James Taylor, Lonne Heijmans, Jason T. Ross
Publikováno v:
Journal of neuroscience methods. 307
Background Electroencephalography (EEG) invariably contains extra-cranial artifacts that are commonly dealt with based on qualitative and subjective criteria. Failure to account for EEG artifacts compromises data interpretation. New Method We have de
Autor:
Xi C. He, Chu-Xia Deng, Tomer Itkin, Tsvee Lapidot, John M. Perry, Jason T. Ross, Linheng Li, Aparna Venkatraman, Mark Hembree, Meng Zhao, Jeffrey S. Haug
Publikováno v:
Blood. 120:1831-1842
Previous studies have shown that fibroblast growth factor (FGF) signaling promotes hematopoietic stem and progenitor cell (HSPC) expansion in vitro. However, it is unknown whether FGF promotes HSPC expansion in vivo. Here we examined FGF receptor 1 (
Publikováno v:
Pharmacology Biochemistry and Behavior. 91:461-467
The nicotinic partial agonist varenicline (VCL) is a recently approved medication for the treatment of tobacco dependence, yet very little preclinical research on this drug has been published. The present experiment examined the nicotinic partial ago
Publikováno v:
European Journal of Pharmacology. 559:173-179
The dopamine D 3 receptor is primarily localized within the mesocorticolimbic system, and may therefore have potential as a pharmacotherapeutic target for the treatment of drug dependence. Studies have shown that the selective dopamine D 3 receptor a
Autor:
Beth A. Reboussin, Amy Hauck Newman, Renee Claytor, Jason T. Ross, Michael A. Nader, Jennifer L. Martelle
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 321:573-582
The present study examined the effects of two novel dopamine D3 receptor compounds, NGB 2904 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide], an antagonist, and CJB 090 [N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-
Publikováno v:
Drug and Alcohol Dependence. 78:135-140
The purpose of the present study was to compare the reinforcing efficacy of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to cocaine. Rhesus monkeys (n=4) responded under a within-session, exponentially increasing, progressive-ratio (PR) schedu
Publikováno v:
Shock. 12:215-221
Interferon-gamma (IFN-gamma) has been implicated in the mortality of animal models of endotoxemia. On the other hand, the specific role of IFN-gamma in the development of organ inflammation in a model of polymicrobial sepsis has not been elucidated.