Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jason T. McConville"'
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 153:14-22
Tuberculosis is still one of the leading causes of death from a single infectious agent (i.e. Mycobacterium tuberculosis). First line therapy includes per oral administration of high doses of rifampicin over several months and is often times accompan
Publikováno v:
Expert Opinion on Drug Delivery. 17:305-322
Introduction: Recently, tuberculosis was reported as the leading cause of death from a single infectious agent. Standard therapy includes administration of four first-line antibiotics, i.e. rifampicin, isoniazid, ethambutol, and pyrazinamide over a p
Publikováno v:
International journal of pharmaceutics. 590
Rifampicin is an antibiotic used in tuberculosis therapy showing extensive (solvato-) polymorphism. Per oral administration of high doses is recommended, but application as dry powder for inhalation at the site of infection being the lungs, is desira
Publikováno v:
Molecular pharmaceutics. 17(5)
The induction port (IP) for aerosol analysis with the Next Generation Pharmaceutical Impactor as monographed in the United States and European pharmacopoeia (USPIP) lacks physiological relevance, which, amongst other reasons, has been identified as c
Autor:
Elena Del Favero, Alessandra Rossi, Eleonore Fröhlich, Jason T. McConville, Francesca Rossi, Ruggero Bettini, Irene Rossi, Francesca Buttini, Fabio Sonvico, Sarah Zellnitz
Publikováno v:
European journal of pharmaceutical sciences 113 (2018): 159–170. doi:10.1016/j.ejps.2017.10.024
info:cnr-pdr/source/autori:Rossi, Irene; Sonvico, Fabio; McConville, Jason T.; Rossi, Francesca; Froehlich, Eleonore; Zellnitz, Sarah; Rossi, Alessandra; Del Favero, Elena; Bettini, Ruggero; Buttini, Francesca/titolo:Nebulized coenzyme Q(10) nanosuspensions: A versatile approach for pulmonary antioxidant therapy/doi:10.1016%2Fj.ejps.2017.10.024/rivista:European journal of pharmaceutical sciences/anno:2018/pagina_da:159/pagina_a:170/intervallo_pagine:159–170/volume:113
info:cnr-pdr/source/autori:Rossi, Irene; Sonvico, Fabio; McConville, Jason T.; Rossi, Francesca; Froehlich, Eleonore; Zellnitz, Sarah; Rossi, Alessandra; Del Favero, Elena; Bettini, Ruggero; Buttini, Francesca/titolo:Nebulized coenzyme Q(10) nanosuspensions: A versatile approach for pulmonary antioxidant therapy/doi:10.1016%2Fj.ejps.2017.10.024/rivista:European journal of pharmaceutical sciences/anno:2018/pagina_da:159/pagina_a:170/intervallo_pagine:159–170/volume:113
Coenzyme Q(10) (CoQ(10)) is an antioxidant substance indicated as a dietary supplement which has been proposed as adjuvant in the treatment of cardiovascular disorders and cancer for its protective and immunostimulating activities. The aim of this wo
Publikováno v:
International Journal of Pharmaceutics. 535:402-409
Based on a computer tomographic scan of a human trachea, a modified induction port (mIP), for use with the Next Generation Cascade Impactor, was manufactured using 3D printing technology. Standard United States Pharmacopoeia IP (USPIP) was compared t
Publikováno v:
Drug Development and Industrial Pharmacy. 44:868-871
Publikováno v:
International Journal of Pharmaceutics. 514:407-419
Coenzyme Q10 (CoQ10) is a poorly-water soluble compound that is being investigated for the treatment of carcinomas. The aim of this study was to investigate the feasibility of preparing phospholipid-stabilized dispersions of the anticancer agent for
Publikováno v:
Journal of Pharmacy and Pharmacology. 68:556-578
Objectives In this review paper, we explore the interaction between the functioning mechanism of different nebulizers and the physicochemical properties of the formulations for several types of devices, namely jet, ultrasonic and vibrating-mesh nebul
Autor:
Masahiro Sakagimi, Anthony J. Hickey, Jason T. McConville, Phil J. Kuehl, Andrew Reginald Clark, Jayne E. Hastedt, Peter J. Mauser, William H. Doub, Jeffry G. Weers, Claus-Michael Lehr, Ralph Niven, Guenther Hochhaus, Per Bäckman
Publikováno v:
AAPS Open, Vol 2, Iss 1, Pp 1-20 (2016)
The Biopharmaceutics Classification System (BCS), developed in the 1990s for oral immediate release drugs, is utilized by R&D scientists and regulators to streamline product development and regulatory approval timelines. This elegant, science-based a