Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jason T. Godfrey"'
Autor:
Ryan B. Corcoran, Theodore S. Hong, Alberto Bardelli, A. John Iafrate, Jochen K. Lennerz, David P. Ryan, Lawrence S. Blaszkowsky, Jeffrey W. Clark, Nicholas A. Jessop, Jason T. Godfrey, Darrell R. Borger, Benedetta Mussolin, Giulia Siravegna, Leanne G. Ahronian, Eunice L. Kwak
Supplementary Figure S1. Absence of ALK or ROS1 rearrangements in Patient #3. Supplementary Figure S2. CT images for Patient #5. Supplementary Figure S3. Interlesional heterogeneity in a HER2-amplified EGC patient. Supplementary Table S1. 40 gene cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c25688491b68e9bba0589ab1bbe77ed
https://doi.org/10.1158/2159-8290.22531379.v1
https://doi.org/10.1158/2159-8290.22531379.v1
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S5. Role of ARAF Q489L and MEK F53L in resistance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159b92665530fed33babe57bbb3fb25d
https://doi.org/10.1158/2159-8290.22530041.v1
https://doi.org/10.1158/2159-8290.22530041.v1
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Table S1. Patient characteristics and MAPK pathway reactivating resistance mechanisms of BRAF-mutant CRC patients with clinical acquired resistance to RAF/EGFR or RAF/MEK inhibitor combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68672d23e9c3704897ff3623acae1192
https://doi.org/10.1158/2159-8290.22530038
https://doi.org/10.1158/2159-8290.22530038
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Table S2. Summary of variant calls from WES analysis of matched pre-treatment and post-progression biopsies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508ebe7535916250464f6736fff903e5
https://doi.org/10.1158/2159-8290.22530032
https://doi.org/10.1158/2159-8290.22530032
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S1. KRAS FISH analysis of parental and resistance cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75becf461b17f10518263a39fea2b15
https://doi.org/10.1158/2159-8290.22530053
https://doi.org/10.1158/2159-8290.22530053
Autor:
David A. Barbie, William C. Hahn, Kwok-Kin Wong, Ryan B. Corcoran, Jeffrey A. Engelman, Michael J. Eck, Suzanne Gaudet, Nir Hacohen, Shuji Ogino, William E. Gillanders, Jill P. Mesirov, Lior Rozhansky, Mary T. Labowsky, Whitney Silkworth, Edmond M. Chan, Karolina Maciag, Asher N. Page, Zhi Rong Qian, Jason T. Godfrey, Pablo Tamayo, Jacob B. Reibel, Tran C. Thai, Anna C. Schinzel, Rhine R. Shen, Susan E. Moody, Shenghong Yang, Yu Imamura, Thanh U. Barbie, Travis J. Cohoon, Amir R. Aref, Zehua Zhu
PDF file 146K, This file contains the legends to Supplementary Figures 1-7 and Supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333c077e9ee3f485c8ade53fb1b04705
https://doi.org/10.1158/2159-8290.22529976.v1
https://doi.org/10.1158/2159-8290.22529976.v1
Autor:
David A. Barbie, William C. Hahn, Kwok-Kin Wong, Ryan B. Corcoran, Jeffrey A. Engelman, Michael J. Eck, Suzanne Gaudet, Nir Hacohen, Shuji Ogino, William E. Gillanders, Jill P. Mesirov, Lior Rozhansky, Mary T. Labowsky, Whitney Silkworth, Edmond M. Chan, Karolina Maciag, Asher N. Page, Zhi Rong Qian, Jason T. Godfrey, Pablo Tamayo, Jacob B. Reibel, Tran C. Thai, Anna C. Schinzel, Rhine R. Shen, Susan E. Moody, Shenghong Yang, Yu Imamura, Thanh U. Barbie, Travis J. Cohoon, Amir R. Aref, Zehua Zhu
S1 XLSX file 63K, This Supplementary Table contains the results of ORF screen to identify genes that can rescue the suppression of TBK1 in a KRAS-dependent cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209d5b3de765d71370d93b113a465be1
https://doi.org/10.1158/2159-8290.22529973
https://doi.org/10.1158/2159-8290.22529973
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S2. KRAS mutation drives resistance to RAF inhibitor combinations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f9e57f074e6af28b8bf210e87b35fb
https://doi.org/10.1158/2159-8290.22530050
https://doi.org/10.1158/2159-8290.22530050
Autor:
Ryan B. Corcoran, Levi A. Garraway, Jeffrey A. Engelman, A. John Iafrate, Dora Dias-Santagata, Gad Getz, Mari Mino-Kenudson, Tiffany G. Huynh, Niall J. Lennon, Lisa M. Green, Kristin Anderka, Samira Bahl, Joseph M. Gurski, Anuj Kalsy, Elizabeth L. Lockerman, Craig H. Mermel, Kerry D. Lynch, Koki Nishimura, Jason T. Godfrey, Jason E. Faris, Eunice L. Kwak, Nikhil Wagle, Eliezer M. Van Allen, Erin M. Sennott, Leanne G. Ahronian
Supplementary Figure S3. Copy number alterations for Patient #1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3aa5fa97deb80db2a5be43d4f9f8a9
https://doi.org/10.1158/2159-8290.22530047
https://doi.org/10.1158/2159-8290.22530047
Autor:
David A. Barbie, William C. Hahn, Kwok-Kin Wong, Ryan B. Corcoran, Jeffrey A. Engelman, Michael J. Eck, Suzanne Gaudet, Nir Hacohen, Shuji Ogino, William E. Gillanders, Jill P. Mesirov, Lior Rozhansky, Mary T. Labowsky, Whitney Silkworth, Edmond M. Chan, Karolina Maciag, Asher N. Page, Zhi Rong Qian, Jason T. Godfrey, Pablo Tamayo, Jacob B. Reibel, Tran C. Thai, Anna C. Schinzel, Rhine R. Shen, Susan E. Moody, Shenghong Yang, Yu Imamura, Thanh U. Barbie, Travis J. Cohoon, Amir R. Aref, Zehua Zhu
PDF file 1227K, This file contains Supplemental Figures 1-7, which provide additional supporting information for each of the main figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5893bfbe1091c688be62ffa4ec13995c
https://doi.org/10.1158/2159-8290.22529979
https://doi.org/10.1158/2159-8290.22529979