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of 4
pro vyhledávání: '"Jason Spaeth"'
Autor:
Matthew P. Gruntorad, Mark P. Vrtiska, Christopher J. Chizinski, Jennifer N. Duberstein, David C. Fulton, Howard W. Harshaw, Andrew H. Raedeke, Jason Spaeth
Publikováno v:
Wildlife Society Bulletin, Vol 48, Iss 1, Pp n/a-n/a (2024)
Abstract Due to the steady decline of duck hunter participation, several studies have investigated means to bolster the duck hunter population. Researchers and wildlife professionals have assumed that simpler regulations would attract new and unconfi
Externí odkaz:
https://doaj.org/article/857afc43bef84a79a561b65ecc935988
Publikováno v:
Diabetes. 71
During diabetes progression, a subset of failing β-cells incurs a loss of transcription factors (TFs) such as Pdx1, which drives expression of numerous β-cell functional genes including Ins2, MafA, and Slc2a2. Like other TFs, Pdx1 requires the recr
Publikováno v:
Diabetes. 71
The main function of the pancreatic β-cell is glucose-stimulated insulin secretion (GSIS) which serves to maintain whole body glucose homeostasis. Under type 2 diabetic conditions, a subset of β-cells fail and lose expression of key transcription f
Autor:
Carlos Perez-Cervantes, Jeffery S. Tessem, Sunyoung Shin, Jason Spaeth, Mary E. Rabaglia, Jeea Choi, Linsin A Smith, Christina Kendziorski, Roland Stein, Alan D. Attie, Shane P Simonett, Kathryn L. Schueler, Mark P. Keller, Jacob A. Herring, Sunduz Keles, Donnie S. Stapleton, Ivan P. Moskowitz, Matthew N. Bernstein, Rhonda Bacher, Chenyang Dong, Daniel R Turkewitz
Publikováno v:
J Clin Invest
The transcription factor NFATC2 induces β cell proliferation in mouse and human islets. However, the genomic targets that mediate these effects have not been identified. We expressed active forms of Nfatc2 and Nfatc1 in human islets. By integrating