Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jason Sotzen"'
Autor:
Coline Gaillard, Taku A. Tokuyasu, Galit Rosen, Jason Sotzen, Adeline Vitaliano-Prunier, Ritu Roy, Emmanuelle Passegué, Hugues de Thé, Maria E. Figueroa, Scott C. Kogan
Publikováno v:
Haematologica, Vol 100, Iss 8 (2015)
Acute promyelocytic leukemia is an aggressive malignancy characterized by the accumulation of promyelocytes in the bone marrow. PML/RARA is the primary abnormality implicated in this pathology, but the mechanisms by which this chimeric fusion protein
Externí odkaz:
https://doaj.org/article/4e7566ae589c4769b0334a3456f24838
Autor:
Inderdeep Gakhal, Tarek Haykal, Ahmed Abdalla, Ragheed Al-Dulaimi, Babikir Kheiri, Varun Samji, Areeg Bala, Jason Sotzen, Yazan Zayed, Ghassan Bachuwa
Publikováno v:
Journal of the National Comprehensive Cancer Network. 17:CLO19-035
Background: Metastatic clear-cell renal cell carcinoma (RCC) is largely incurable, and its treatment remains challenging. Sunitinib, a tyrosine kinase inhibitor, is one of the current standard-of-care options for treatment-naïve patients with metast
Autor:
Kalpana Raja, Keylonnie Miller, James T. Elder, Lam C. Tsoi, Johann E. Gudjonsson, Jason Sotzen, Matthew Patrick
Publikováno v:
Journal of Investigative Dermatology. 139:683-691
Immune-mediated diseases affect more than 20% of the population, and many autoimmune diseases affect the skin. Drug repurposing (or repositioning) is a cost-effective approach for finding drugs that can be used to treat diseases for which they are cu
Autor:
Parker Suit, Htay Htay Kyi, Huda Marcus, James Cranford, Ghassan Bachuwa, Saira Sundus, Philip J. McDonald, Jason Sotzen
Publikováno v:
BMJ Open Quality
IntroductionElectronic medication reconciliation systems are known to reduce medication errors. We hypothesised that refinement of the electronic medical record (EMR) and provider education could improve adherence to completion of admission medicatio
Autor:
Stephen D. Nimer, Maria E. Figueroa, Tingting Qin, Ross L. Levine, Franck Rapaport, Virginia M. Klimek, Raajit K. Rampal, Jason Sotzen
Publikováno v:
Leukemia
Autor:
Inderdeep Gakhal, Tarek Haykal, Varun Samji, Ragheed Al-Dulaimi, Ranine Ghamrawi, Khalil Katato, Rizwan Danish, Jason Sotzen, Yazan Zayed, Areeg Bala
Publikováno v:
Journal of Clinical Oncology. 37:e16067-e16067
e16067 Background: Metastatic clear-cell renal cell carcinoma (RCC) is largely incurable, and its treatment remains challenging. Sunitinib, a tyrosine kinase inhibitor, is one of the current standard-of-care options for treatment-naïve patients with
Autor:
Nathalie Droin, Bernardino Allione, Francesca Buchi, Eric Solary, Dorothée Selimoglu-Buet, Maria E. Figueroa, Omar Abdel-Wahab, Erico Masala, Monia Lunghi, Tingting Qin, Antonella Poloni, Jean Baptiste Micol, Daniela Gioia, Jason Sotzen, Valeria Santini, Kristen Meldi
Publikováno v:
The Journal of clinical investigation. 125(5)
Myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML) are characterized by mutations in genes encoding epigenetic modifiers and aberrant DNA methylation. DNA methyltransferase inhibitors (DMTis) are used to treat these disorders, but r
Autor:
Kenneth P, Mitton, Alvaro E, Guzman, Mrinalini, Deshpande, David, Byrd, Camryn, DeLooff, Kristina, Mkoyan, Paul, Zlojutro, Adrianne, Wallace, Brandon, Metcalf, Kirsten, Laux, Jason, Sotzen, Trung, Tran
Publikováno v:
Molecular Vision
Purpose The histone-deacetylase inhibitor activity of valproic acid (VPA) was discovered after VPA’s adoption as an anticonvulsant. This generated speculation for VPA’s potential to increase the expression of neuroprotective genes. Clinical trial
Autor:
James R. Downing, Yushan Li, Shann Ching Chen, Mondira Kundu, Charles G. Mullighan, Ari Melnick, Maria E. Figueroa, Jason Sotzen, Letha A. Phillips, Anna Andersson
Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy and is characterized by recurring structural genetic alterations. Previous studies of DNA methylation suggest epigenetic alterations may also be important, but an integrated gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97231cdc0a567687f822090701896e90
https://europepmc.org/articles/PMC3696550/
https://europepmc.org/articles/PMC3696550/
Autor:
Francesca Buchi, Omar Abdel-Wahab, Valeria Santini, Jean-Baptiste Micol, Monia Lunghi, Antonella Poloni, Tingting Qin, Kristen Meldi, Bernadino Allione, Jason Sotzen, Erico Masala, Daniela Gioia, Maria E. Figueroa
Publikováno v:
Blood. 124:4598-4598
Myelodysplastic syndromes (MDS) and the related disorder chronic myelomonocytic leukemia (CMML) are characterized by abnormal DNA hypermethylation and the DNA methyltransferase inhibitors (DMTis) azacytidine and decitabine (DAC) are frequently used a