Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jason Shao"'
Autor:
Husam Taher, Eisa Mahyari, Craig Kreklywich, Luke S Uebelhoer, Matthew R McArdle, Matilda J Moström, Amruta Bhusari, Michael Nekorchuk, Xiaofei E, Travis Whitmer, Elizabeth A Scheef, Lesli M Sprehe, Dawn L Roberts, Colette M Hughes, Kerianne A Jackson, Andrea N Selseth, Abigail B Ventura, Hillary C Cleveland-Rubeor, Yujuan Yue, Kimberli A Schmidt, Jason Shao, Paul T Edlefsen, Jeremy Smedley, Timothy F Kowalik, Richard J Stanton, Michael K Axthelm, Jacob D Estes, Scott G Hansen, Amitinder Kaur, Peter A Barry, Benjamin N Bimber, Louis J Picker, Daniel N Streblow, Klaus Früh, Daniel Malouli
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008666 (2020)
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal models using host-specific CMVs. Infection of rhesus macaques (RM) with
Externí odkaz:
https://doaj.org/article/18b74986983c43189be2f692f0340704
Autor:
Lindsay N Carpp, Youyi Fong, Matthew Bonaparte, Zoe Moodie, Michal Juraska, Ying Huang, Brenda Price, Yingying Zhuang, Jason Shao, Lingyi Zheng, Laurent Chambonneau, Robert Small, Saranya Sridhar, Carlos A DiazGranados, Peter B Gilbert
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234236 (2020)
We previously showed that Month 13 50% plaque reduction neutralization test (PRNT50) neutralizing antibody (nAb) titers against dengue virus (DENV) correlated with vaccine efficacy (VE) of CYD-TDV against symptomatic, virologically-confirmed dengue (
Externí odkaz:
https://doaj.org/article/97e45ef310474973a6a72c954d268e82
Autor:
Douglas S Ramsay, Salwa Al-Noori, Jason Shao, Brian G Leroux, Stephen C Woods, Karl J Kaiyala
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124740 (2015)
Considerable data suggest that individuals who appear minimally disrupted during an initial drug administration have elevated risk for abusing the drug later. A better understanding of this association could lead to more effective strategies for prev
Externí odkaz:
https://doaj.org/article/e011e13e17a54d63afcfe3a84f785954
Autor:
Betzana Zambrano, Fernando Noriega, Nicholas Jackson, Youyi Fong, Laurent Chambonneau, Alex Luedtke, Michal Juraska, Sophie Pallardy, Jason Shao, Ying Huang, Yingying Zhuang, Peter B. Gilbert, Zoe Moodie, Alain Bouckenooghe, Carina Frago, Lindsay N. Carpp
Publikováno v:
Am J Trop Med Hyg
The CYD-TDV vaccine is licensed in multiple endemic countries based on vaccine efficacy (VE) against symptomatic, virologically confirmed dengue demonstrated in two phase 3 trials (CYD14, 2- to 14-year-olds, Asia; CYD15, 9- to 16-year-olds, Latin Ame
CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification
Autor:
Paul T. Edlefsen, Brandon F. Keele, Louis J. Picker, Alejandra Marenco, Jeremy Smedley, Jacob D. Estes, Kathleen Busman-Sahay, Roxanne M. Gilbride, Haesun Park, Miles P. Davenport, Mykola Pinkevych, Michael Nekorchuk, Yoshinori Fukazawa, Afam A. Okoye, Benjamin Varco-Merth, Morgan Chaunzwa, Andrea N. Selseth, Hannah Behrens, Michael K. Axthelm, Jeffery D. Lifson, Jason Shao, Scott G. Hansen, Derick D. Duell, Romas Geleziunas
Publikováno v:
J Clin Invest
To define the contribution of CD8(+) T cell responses to control of SIV reactivation during and following antiretroviral therapy (ART), we determined the effect of long-term CD8(+) T cell depletion using a rhesusized anti-CD8β monoclonal antibody on
Autor:
Richard Green, Julia C. Ford, Jeffrey D. Lifson, David Morrow, Emily Ainslie, Rafick-Pierre Sekaly, Kurt T. Randall, William J. Bosche, Barbara K. Felber, Michael K. Axthelm, Colette M. Hughes, Louis J. Picker, Daniel J. Newhouse, Paul T. Edlefsen, Jason Shao, Scott G. Hansen, Yoshinori Fukazawa, Wenjun Song, Roxanne M. Gilbride, Andrea N. Selseth, Kelli Oswald, Jan Komorowski, Fredrik Barrenäs, Xinxia Peng, Connor B. Driscoll, George N. Pavlakis, Leanne S. Whitmore, Rebecca Shoemaker, Inah Golez, Taryn Urion, Slim Fourati, Bryan E. Randall, Lynn Law, Elise Smith, Michael Gale, Ewelina Kosmider, Randy Fast, Jean Chang
Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent clearance of highly pathog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75e7442361986b0d9e8e5f5642b19b84
https://doi.org/10.1101/2021.01.11.426199
https://doi.org/10.1101/2021.01.11.426199
Autor:
Travis Whitmer, Jason Shao, Scott G. Hansen, Richard J. Stanton, Xiaofei E, Paul T. Edlefsen, Lesli M. Sprehe, Hillary C. Cleveland-Rubeor, Amitinder Kaur, Matilda J. Moström, Matthew R. McArdle, Colette M. Hughes, Peter A. Barry, Daniel Malouli, Andrea N. Selseth, Michael Nekorchuk, Eisa Mahyari, Jacob D. Estes, Michael K. Axthelm, Kerianne A. Jackson, Craig N. Kreklywich, Daniel N. Streblow, Yujuan Yue, Timothy F. Kowalik, Jeremy Smedley, Klaus Früh, Husam Taher, Benjamin N. Bimber, Luke S. Uebelhoer, Amruta Bhusari, Dawn L. Roberts, Louis J. Picker, Kimberli A. Schmidt, Elizabeth A. Scheef, Abigail B. Ventura
Publikováno v:
PLoS Pathogens
PLoS pathogens, vol 16, iss 11
PLoS Pathogens, Vol 16, Iss 11, p e1008666 (2020)
PLoS pathogens, vol 16, iss 11
PLoS Pathogens, Vol 16, Iss 11, p e1008666 (2020)
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal models using host-specific CMVs. Infection of rhesus macaques (RM) with
Autor:
Michael K. Axthelm, Klaus Früh, Julia C. Ford, Jeffrey D. Lifson, Ravi Iyer, Louis J. Picker, William J. Bosche, Nessy John, Roxanne M. Gilbride, Daniel Malouli, Shaheed Abdulhaqq, Brian Berkemeier, Abigail B. Ventura, Jennie Womack, David Morrow, Kelli Oswald, Isabel Scholz, Jonah B. Sacha, Jason Shao, Scott G. Hansen, Michael Hull, Andrea N. Selseth, Paul T. Edlefsen, Colette M. Hughes, Rebecca Shoemaker, Marieke C. Verweij
Publikováno v:
Science
Strain 68-1 rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens elicit CD8+ T cells that recognize peptide epitopes presented by major histocompatibility complex (MHC)-II and MHC-E molecules, instead of MHC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a670a6b344703a0c7f467acda178d8
https://doi.org/10.1101/2020.09.30.321158
https://doi.org/10.1101/2020.09.30.321158
Autor:
Justin M. Greene, Renee G. Espinosa Trethewy, Abigail B. Ventura, Husam Taher, Brian Berkemeier, Luke S. Uebelhoer, Jay A. Nelson, Finn Grey, Colette M. Hughes, Rebecca Shoemaker, Daniel Malouli, Courtney R. Papen, William J. Bosche, Louis J. Picker, David Morrow, Meaghan H. Hancock, Roxanne M. Gilbride, Michael Hull, Michael K. Axthelm, Julia C. Ford, Paul T. Edlefsen, Jonah B. Sacha, Daniel N. Streblow, Kurt T. Randall, Jason Shao, Scott G. Hansen, Jeffrey D. Lifson, Kelli Oswald, Matthew R. McArdle, Klaus Früh
Publikováno v:
Malouli, D, Hansen, S G, Hancock, M H, Hughes, C M, Ford, J C, Gilbride, R M, Ventura, A B, Morrow, D, Randall, K T, Taher, H, Uebelhoer, L S, McArdle, M R, Papen, C R, Espinosa Trethewy, R, Oswald, K, Shoemaker, R, Berkemeier, B, Bosche, W J, Hull, M, Greene, J M, Axthelm, M K, Shao, J, Edlefsen, P T, Grey, F, Nelson, J A, Lifson, J D, Streblow, D, Sacha, J B, Früh, K & Picker, L J 2021, ' Cytomegaloviral determinants of CD8+ T cell programming and RhCMV/SIV vaccine efficacy ', Science Immunology, vol. 6, no. 57, eabg5413 . https://doi.org/10.1126/sciimmunol.abg5413
Simian immunodeficiency virus (SIV) insert-expressing, 68-1 Rhesus Cytomegalovirus (RhCMV/SIV) vectors elicit major histocompatibility complex (MHC)-E- and -II-restricted, SIV-specific CD8+ T cell responses, but the basis of these unconventional resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6054cac299f3617d6d4f213b423984f
https://doi.org/10.1101/2020.09.30.321349
https://doi.org/10.1101/2020.09.30.321349
Autor:
Susan Buchbinder, Richard M. Novak, Paul T. Edlefsen, Mary Allen, Gabriela Diaz, Marcel E Curlin, Janine Maenza, Michael C. Keefer, Cecilia Morgan, Stephen C. De Rosa, Jason Shao, Ann Duerr, Kenneth H. Mayer, Lawrence Corey
Publikováno v:
Vaccine
BACKGROUND: Vaccine-induced mucosal immune responses may be critical for protection against HIV infection, but may also result in short or long-term changes that enhance susceptibility to infection in some individuals, such as those with baseline ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17ce24f0d0b70c28a5931c9d03aa0b6
https://europepmc.org/articles/PMC8357155/
https://europepmc.org/articles/PMC8357155/